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FBO DAILY ISSUE OF JANUARY 05, 2002 FBO #0034
PRESOLICITATION NOTICE

B -- Clinical Pediatric Cardiologist

Notice Date

1/3/2002
 

Notice Type

Presolicitation Notice
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, MD, 20892-7902
 

ZIP Code

20892-7902
 

Solicitation Number

NHLBI-PS-2002-025
 

Response Due

1/14/2002
 

Archive Date

1/29/2002
 

Point of Contact

Cecilia Morales, Purchasing Agent, Phone (301) 435-0366, Fax (301) 480-3345, - Debra Hawkins, Chief, Procurement Section, Phone (301) 435-0366, Fax (301) 480-3345,
 

E-Mail Address

cm71f@nih.gov, dh41g@nih.gov
 

Description

The National Heart, Lung, and Blood Institute intends to negotiate on a non-competitive basis with the Children's Hospital National Medical Center, 111 Michigan Avenue, N.W., Washington, D.C. 20010, to provide a board certified pediatric cardiologist with demonstrated clinical experience, and proven research expertise in the study of cardiovascular structure and function in vertebrate embryos. Background Information: The Laboratory of Development Biology is initiating a new project to identify novel gene and genetic pathway essential for mammalian heart development. This gene discovery based project will entail using ultrasound imaging to conduct a high throughput screen for cardiovascular anomalies in mutagenized mice. Mouse mutations identified in this manner will aid in the mapping and identification of novel genes that are essential for cardiovascular development. Purpose and Objectives for the Procurement: The specific objective of this research is the identification of recessive lethal mouse mutations that cause heart defects. A clinical pediatric cardiologist with knowledge and research experience in cardiovascular developmental embryology will greatly facilitate the identification of novel mouse mutations causing cardiovascular anomalies of clinical significance. Requirements: The pediatric cardiologist will help develop a protocol for the high through put screen and define the specific parameters to be analyzed. Of particular importance is expertise in the use of various imaging modalities for the analysis of fetal mouse heart development and function, and the ability to relate cardiovascular phenotypes in mouse models to clinical cardiovascular congenital anomalies and pathology. The individual will assist in defining the screening protocol, and train the person who will actually conduct the high through put screen at the Jackson Laboratory. In addition, the Pediatric Cardiologist will help analyze the ultrasound data gathered from the mutagenized mice, and based on this evaluation, determine which mutagenized mouse lines are to be brought back to NHLBI for further analysis. The Pediatric Cardiologist will undertake a detailed analysis of cardiovascular structure and function using imaging modalities including MRI micro-CT, micro-PET, and Doppler echocardiography. Government Responsibilities: The Laboratory of Developmental Biology in DIR, NHLBI, NIH, will provide all of the equipment, computer hardware and software required for this project. The work of this individual will be reviewed and approved by the Project Officer. Reporting Requirements and Deliverables: The pediatric cardiologist will present the progress to date on a monthly basis in a seminar style presentation to the laboratory, and in particular will discuss the potential clinical relevance of any cardiovascular phenotypes observed amongst the mutagenized mice. When appropriate, the work will be written up as manuscripts for publication. Period of Performance: The period of performance is January 2002 through December 2002. This acquisition is being conducted under simplified acquisition procedures and is exempt from the requirement of Federal Acquisition Regulations (FAR) Part 6, Competition Requirements. The North American Industry Classification System (NAICS) applicable to this requirement is 541710. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this requirement. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct future competitive procurement. Responses to this announcement, referencing synopsis number NHLBI-PS-2002-025, may be submitted by mail to the National Heart, Lung, and Blood Institute, Contracts Operations Branch, Procurement Section, 6701 Rockledge Drive, Rockledge Building 2, Suite 6042, Bethesda, Maryland 20892-7902, Attention: Cecilia Morales. All responsible sources may submit a proposal, which if timely received, shall be considered by the agency.
 

Place of Performance

Address: Bethesda, Maryland

Zip Code: 20892

Country: USA
 

Record

SN20020105/00010989-020104090132 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(will not be valid after Archive Date)

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