Loren Data's SAM Daily™

FBO DAILY ISSUE OF MARCH 13, 2002 FBO #0101
SOLICITATION NOTICE

R -- Investigations of organization and function of centromeric and telomeric...

Notice Date

3/11/2002
 

Notice Type

Solicitation Notice
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Room 604, Rockville, MD, 20852
 

ZIP Code

20852
 

Solicitation Number

RFQ-NCI-20025-NG
 

Response Due

3/25/2002
 

Archive Date

4/9/2002
 

Point of Contact

Malinda Holdcraft, Purchasing Agent, Phone (301) 402-4509, Fax (301) 402-4513, - Caren Rasmussen, Lead Contract Specialist, Phone (301) 402-4509, Fax (301) 402-4513,
 

E-Mail Address

mh139x@nih.gov, rasmusc@mail.nih.gov
 

Description

The National Cancer Institute (NCI), Laboratory of Biosystems and Cancer (LBC), Genome Structure and Function Section (GSFS) is a central NCI resource for investigating the organization and function of centromeric and telomeric regions of human chromosomes, for characterizing human disease genes and for developing new methods to facilitate these goals. One of the main projects in LBC relates to Human Genome Initiative and includes isolation and characterization of segments missing from the draft human genome sequence. The GSFS plans to enter into a sole source contract with Mr. Jung-Hyun Kim, 840 Hadan-Dong Saha-Ku, Pusan, Korea 604-714. This procurement will provide expert isolation of segments missing from the draft human genome sequence by Transformation-Associated Recombination (TAR) cloning in yeast. The Genome Structure and Function Section is in collaboration with Dr. Sun-Hee Leem at the Department of Biology and the College of Natural Sciences, Pusan, South Korea. Mr. Jung-Hyun Kim is a research assistant in the laboratory of Dr. Leem in South Korea and in the USA. The main scientific interest and expertise of this laboratory is new technologies for direct isolation of large chromosomal fragments from mammalian genomes for structural and functional studies. During the last year, Mr. Kim has worked on a number of collaborative projects for four months in NCI, LBC and eight months at the Department of Biology of the College of Natural Sciences in South Korea. He has also participated in a project on optimization of selective capture of human genes by a TAR cloning technique. Results of this work are summarized in two papers one of which has been recently published in Oncogene. Mr. Jung-Hyun Kim has expertise in investigating optimal conditions for selective isolation of human genes by TAR cloning techniques. TAR cloning techniques are non standard, hard to master and require long periods of training. Mr. Kim is well versed in the techniques that the NCI LBC are utilizing to complete human genome sequencing. The results of this work will form a foundation to generate the first contiguous DNA sequence of entire human chromosomes. The results also form a foundation to discovery of new human genes and to study of organization of human centromere. Mr. Jung-Hyun Kim is the only source known to the NCI researcher who is intimately involved with the techniques that are required to complete human genome sequencing relating to the laboratory. This is not a solicitation for competitive quotations. However, if any interested party believes it can provide the above services, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Capability statements must be received in the contracting office by 2:00 PM EST, on March 25, 2002. For further information please contact Malinda Holdcraft, Purchasing Agent, (301)-402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Faxed copies of capability statements will not be accepted. No collect calls.
 

Place of Performance

Address: NIH/NCI, 9000 Rockville Pike, Bethesda, MD

Zip Code: 20892

Country: USA
 

Record

SN00038947-W 20020313/020311213209 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

---

| FSG Index  |  This Issue's Index  |  Today's FBO Daily Index Page |