SOLICITATION NOTICE
66 -- SELDI ProteinChip Technology System
- Notice Date
- 12/11/2002
- Notice Type
- Solicitation Notice
- Contracting Office
- Environmental Protection Agency, Ord Service Center/Nerl, Rtp Procurement Operations Division, Research Triangle Park, NC 27711
- ZIP Code
- 27711
- Solicitation Number
- RFQ-RT-03-00046
- Archive Date
- 1/26/2003
- Point of Contact
- Point of Contact, Pamela Smith, Purchasing Agent, Phone (919) 541-0635
- E-Mail Address
-
Email your questions to U.S. Environmental Protection Agency
(smith.pamela@epa.gov)
- Description
- NAICS Code: 334516 The U.S. Environmental Protection Agency (EPA) intends to negotiate a sole source purchase order under Simplified Acquisition Procedures to with Ciphergen Biosystems, Inc., 6611 Dumbarton Circle, Fremont, CA 94555 for the acquisition of a SELDI ProteinChip Technology System. Requirement: (1) The system shall perform surface-enhanced affinity capture(SEAC) using surface-enhanced laser description/ionization (SELDI) for the quantitative analysis of trace components (at low femtomole levels) directly from biological samples. (2) The system shall perform analyses of protein chips comprising arrays of antibodies to capute diagnostic marker proteins directly from biological specimens for identification based on molecular mass. (3) The system shall perform the analysis of one microliter of unfractionated biological fluid as well as extract to provide a protein retentate map with a minimum of 300 features (peaks). (4) The system shall purify proteins from complex biological mixtures directly on the protein chip surface. (5) The system shall perform on-chip molecular processing, including protein purification, peptide mapping, C-terminal, microsequencing and post-translational modification analysis. (6)The system shall provided automated peak integration (digitization) with peak map display and comparison formats for differential protein display. (9) The system shall perform analyses of protein chip molecular arrays in a fully automated mode requiring a minimum of 1000 addressable regions per 2 mm of surface area. (10) The contractor shall provided a one year warranty for each hardware, software, and firmware product delivered. (11) All equipment will be installed on site and familiarization training provided within 60 days of purchase. The unique aspect of the system is its ability to capture important biomolecules (proteins and peptides) directly from the biological sample (such as serum) applied to a chip, wash away contaminants, desorb analytes from the chip and simultaneously analyze for >100 proteins in the sample. This enables one to rapidly identify and screen for biomarkers of effects by comparison of protein "fingerprints" of normal tp "diseased" animals. No other technology is known to have these combined capabilities. EPA believes Ciphergen Biosystem, Inc., is the only vendor capable of satisfying requirements stated above. The circumstance permitting "other than full and open competition" is FAR 6.302-1 "Only one responsible source and no other supplies or services will satisfy Agency requirements". The intent of this notice is to determine if any other source(s) exist, and therefore, no solicitation (RFQ) is available. Consequently, any response failing to provided the aforementioned data and instead choosing to merely submit a routine letter requesting a copy of the RFQ will be ignored. Interested parties who can meet the above requirements may submit written qualification statements, fully explaining their capability no later than 15 days after the date of this publication. Submit response to the U.S. EPA, Attn: Pamela E. Smith (MC-E105-02), RTP Procurement Operations Division, Research Triangle Park, NC 27711. No telephonic or faxed request will be honored.
- Record
- SN00221624-W 20021213/021211213550 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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