SOLICITATION NOTICE
A -- Treatment Units for Research on Neurocognition ans Schizophrenia (TURNS)
- Notice Date
- 3/27/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Mental Health, Contracts Management Branch 6001 Executive Blvd, Rm 6107, MSC 9603, Bethesda, MD, 20892-9603
- ZIP Code
- 20892-9603
- Solicitation Number
- NIMH-03-DM-0003
- Point of Contact
- Suzanne Stinson, Contracting Officer, Phone 301-443-4116, Fax 301-443-0501,
- E-Mail Address
-
ss704b@nih.gov
- Description
- The National Institute of Mental Health (NIMH) proposes to issue a Request for Proposals (RFP) No. NIMH-03-DM-0003 entitled "Treatment Units for Research on Neurocognition and Schizophrenia (TURNS)" under Full and Open Competition procedures using North American Industry Classification System 541720. NIMH seeks the support of a Contractor who will be responsible for the establishment of a network of Treatment Units for Research on Neurocognition and Schizophrenia (TURNS) that will utilize the scientific opportunity created by new insights into the neurobiology of attention, working memory, and other fundamental cognitive processes, to identify and test potential therapeutic agents targeting cognitive deficits in schizophrenia. These treatment units will engage in scientific activities to define experimental designs to evaluate the efficacy of pharmacological strategies to enhance cognition in schizophrenia, identify and select promising compounds and conduct proof of concept and/or phase II clinical trials, and identify and develop opportunities for industry/academia/government collaboration in testing compounds of potential utility in alleviating cognitive deficits in schizophrenia; It is anticipated that the Treatment Units for Research on Neurocognition and Schizophrenia (TURNS) will become national resources where studies of the safety and efficacy of novel compounds targeting cognition in schizophrenia can be conducted in a prompt and cost effective manner. This will be accomplished by building on existing research resources at the host institutions and by combining the necessary expertise in clinical pharmacology, clinical trials and neuropsychology. The TURNS will work as a network of research sites, identify promising potential procognitive therapeutic agents, and conduct high priority clinical studies focused on enhancing neurocognition in schizophrenia including (but not limited to) general safety profile, drug-drug interactions, efficacy (particularly early proof of concept), dose ranges, dose regimen, pharmacokinetics, and effect on other dimensions of symptomatic and behavioral disturbance in schizophrenia. In addition, the TURNS will promote the validation of specific measures of cognition in schizophrenia for use as endpoints in clinical trials and refine methodological approaches for determining the efficacy of compounds for this indication. One of the TURNS ("a leader among peers") will function as a Coordinating Center (Contractor) for the entire project. This lead TURNS shall assemble a team of senior researchers who provide intellectual leadership in Neuropharmacology of Cognition in Schizophrenia. The lead TURNS shall also motivate and lead the contract related activities performed at each TURNS. A thirty-nine (39) month base contract with one (1) option for an additional twenty-four (24) months is contemplated. Plans are to award a contract by September 30, 2003. RFP No. NIMH-03-DM-0003 is scheduled for electronic release on or about April 11, 2003 and the receipt date of proposals is scheduled on or about May 23, 2003. The RFP may be accessed through http://www.fedbizopps.gov or the NIMH home page by using the following instructions: access the home page at http://www.nimh.gov, first select Funding Opportunities, then Contracts, then NIMH Requests for Proposals. It is the offeror's responsibility to monitor the above internet sites for the release of this solicitation and amendments, if any. Please note that the RFP for this requirement will include the Statement of Work, Deliverables, Reporting Requirements, Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offeror will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. All responsible sources are encouraged to submit a proposal that will be considered by the NIMH. This advertisement does not commit the Government to award a contract. Please contact Suzanne Stinson, NIMH Contracting Officer, at 301-443-4116 or ss704b@nih.gov for further information. No collect calls will be accepted.
- Record
- SN00289223-W 20030329/030327213253 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
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