SOLICITATION NOTICE
A -- Development of Enrichment and Selective Culture Media for the Isolation of Special Pathogens from High Priority Foods
- Notice Date
- 5/30/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Division of Construction and Agency Support Contracting, 5630 Fishers Lane, Room 2129, Rockville, MD, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- 223-03-2487
- Response Due
- 7/15/2003
- Archive Date
- 7/30/2003
- Point of Contact
- Ed Arnold, Contract Specialist, Phone (301) 827-7161, Fax (301) 827-7151, - Hamilton Brown, Contract Specialist, Phone (301) 827-7043, Fax (301) 827-7101,
- E-Mail Address
-
earnold@oc.fda.gov, hbrown@oc.fda.gov
- Description
- The Food and Drug Administration, Center for Food Safety and Applied Nutrition, has a requirement for a formal proposal. This synopsis seeks to identify the interest from potential contractors for the ?Development of Enrichment and Selective Culture Media for the Isolation of Special Pathogens from High Priority Foods.? Recent events have reinforced the importance of FDA?s long-standing interest in the development of improved methods for the identification of potential threat agents in foods. CFSAN maintains an active research program for developing and enhancing methodologies to detect and identify microbial hazards that may contaminate food and food products either naturally or through deliberate contamination. Standard protocols for isolation of the most commonly occurring pathogens have been developed. Traditionally, these protocols rely on enrichment and selective culture media for the isolation of a pathogen from the food. CFSAN needs to further enhance its detection and identification capabilities with respect to pathogens that are not typically considered to be foodborne pathogens. Specifically, there is a need to develop bacterial growth media that will improve the recovery of these atypical pathogens from priority food matrices. Initial efforts will focus specifically in the detection of Brucella and Burkholderia species associated with human disease. Statement of Work The contract shall include preliminary assessment of growth and isolation characteristics of pure culture isolates in media from commercial or other sources. Furthermore, selected media preparations which have been found to hold the greatest promise for fulfillment of the goals will be evaluated for use with representative food matrix categories of interest. Independently and not as an agent of the Government, the contractor shall furnish the necessary personnel, materials, services, facilities, and otherwise do all things necessary for or incident to the performance of the work. The contractor shall work closely with CFSAN throughout this requirement. All services shall be provided in a timely manner to help ensure that CFSAN can fulfill its regulatory responsibilities and guard the American public from intentional or accidental contamination of the food supply with these microbiological agents. Task 1 Initially the contractor shall identify those liquid and solid, enrichment and selective media that are available for culture of Brucella abortus, melitensis, and suis (Brucella spp.). These media formulations may be drawn from a number of sources, including, but not limited to commercially available media and the scientific literature. The contractor shall evaluate each solid selective and liquid culture medium formulation for its possible application in culturing Brucella spp. from foods that are representative of several food groups of interest to CFSAN. CFSAN will work with the contractor to identify specific food matrices to be used. It is intended that a few foods will be chosen as representatives of five general food categories or groups that may be defined either by dietary function, composition or storage conditions. For example, milk (high fat), powdered infant formula (dry product, consumption on relevant subpopulation), lettuce (leafy vegetable), shrimp salad (high fat, complex matrix), raspberries (fruit). Upon completion, the contractor shall consult with CFSAN regarding which media hold the greatest potential for use in enrichment and selective culture of Brucella spp. Those enrichment or selective culture media that demonstrate the greatest potential for use with different food matrices will be modified as needed to produce reliable media for enrichment and selective culture of Brucella spp. species from food. Task 2 Initially the contractor shall identify those liquid and solid, enrichment and selective media that are available for culture of Burkholderia mallei and pseudomallei (Burkholderia spp). These media formulations may be drawn from a number of sources, including, but not limited to commercially available media and the scientific literature. The contractor shall evaluate each solid selective and liquid culture medium formulation for its possible application in culturing Burkholderia spp. from foods that are representative of several food groups of interest to CFSAN. CFSAN will work with the contractor to identify specific food matrices to be used. It is intended that a few foods will be chosen as representatives of five general food categories or groups that may be defined either by dietary function, composition or storage conditions. For example, milk (high fat), powdered infant formula (dry product, consumption on relevant subpopulation), lettuce (leafy vegetable), shrimp salad (high fat, complex matrix), raspberries (fruit). Upon completion, the contractor shall consult with CFSAN regarding which media hold the greatest potential for use in enrichment and selective culture of Burkholderia spp. Those enrichment or selective culture media that demonstrate the greatest potential for use with different food matrices will be modified as needed to produce reliable media for enrichment and selective culture of Burkholderia spp. from food. Security Issues All personnel involved in the performance of this task order shall have a secret or higher security clearance. The clearance shall be obtained prior to commencement of any work. Performance of this task order shall be conducted in accordance with the National Industrial Security Program Operating Manual (NISPOM). The manual can be accessed at the following web site: <http://www.dss.mil/isec/nispom.htm>. The offeror shall provide proof of a certified BSL-3 laboratory and trained personnel for work on the project. It is anticipated that this requirement will result in an ID, IQ multi-year contract with task orders. Many of the resulting task orders may be for research relating to bio-terrorism and or counter terrorism issues. Because of the security issues involved in conducting this type of research is will be necessary to classify some of these projects as secret or top-secret. It should be noted that any offeror interested in this procurement must possess the necessary security clearances. The Request for Proposal (RFP) will only be available on the FedBizOpps web page at http://www.fedbizopps.gov/. Prospective offerors are responsible for downloading the RFP and all attachments. It is the offeror's responsibility to monitor the FedBizOpps web page for the release of the solicitation and amendments. The RFP should be available for downloading on/about fifteen (15) days after publication of this announcement and proposals will be due 30 days after issue of the RFP. The FDA reserves the right to award without discussions. Technical questions should be sent to the Contracting Officers e-mail address or fax number contained herein. The NAICS code for this requirement is 541710. Point of Contact - Ed Arnold, Contract Specialist ? Phone 301-827-7161 or Hamilton Brown, Contracting Officer ? Phone 301-827-7043. Food and Drug Administration OFACS/DCASC/COB Attn: Ed Arnold 5630 Fishers Lane, Room 2117, HFA-530 Rockville, Maryland 20857-0001
- Record
- SN00336433-W 20030601/030531233015 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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