SOLICITATION NOTICE
66 -- Instruments and Laboratory Equipment
- Notice Date
- 7/25/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
- ZIP Code
- 20817
- Solicitation Number
- NOI3076
- Response Due
- 8/11/2003
- Archive Date
- 8/26/2003
- Point of Contact
- LaShawn Harris, Purchasing Agent, Phone 301-402-6471, Fax 301-480-3695, - Sylvia Robinson, Purchasing Agent, Phone 301-402-2284, Fax 301-480-3695,
- E-Mail Address
-
lharris@niaid.nih.gov, srobinson@niaid.nih.gov
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are not being requested and a written solicitation will not be issued. The solicitation number for this acquisition is NOI3076 and is being issued as a Notice of Intent (NOI). The incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2001-14. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is not a small business concern. The associated North American Industry Classification System (NAICS) Code 339111, which has a size standard of 500. The National Institute of Allergy and Infectious Diseases intends to procure a Benchtop Magnetic Cell Sorter from the only known manufacture Miltenyi Biotec Inc. The Benchtop Magnetic Cell sorter is proposed as a sole source purchase on the basis that the Cellular Immunology Section is engaged in an effort to isolate very pure, specific cell populations of murine cells with high recovery, including rare cell populations, maintenance of cell viability, rapid sorting capability. The Benchtop Magnetic Cell Sorter has the ability to handle large samples, high throughput and extremely frequent use. This instrument?s technology allows the sorted cell populations to be analyzed by flow cytometry or PCR, in such a way that the magnetic microbeads, on which the technology is based will not interfere with the analysis as they can pass through the flow cytometer without obstruction or do not interfere with PCR amplification. The principle research effort of the Cellular Immunology Section is focused in the area of immune regulation in the pathogenesis and treatment of organ-specific autoimmune disease. The major goal is to further the understanding of the mechanism of action of these regulatory cells in preventing autoimmunity. We have identified a unique population of regulatory CD4+ T-cells which co-express CD25 which are capable of not only suppressing the induction of autoimmune disease in vivo, but also the disease induced by passive transfer of cloned autoantigen-specific effector cells. In order to perform these experiments we have to be able to select for certain populations of murine cells by utilizing a sorting mechanism that will allow further manipulation, testing, and analysis. This system has been utilized within our laboratory for several years. This is the only known system that enables flow cytometry analysis on sorted cells without additional labor to remove the magnetic beads used to sort the cells, which could render the sorted cells unusable for the desired experiments. Loss of this instrument is severely detrimental to the laboratory?s continued research as the majority of our continuing experiments are designed around this technology and it would be cost prohibitive to the laboratory and the overall research goal to alter methodologies. The unique features include the following: 1) Cell sorting can be performed in as little as 15 minutes 2) Ability to separate large numbers of cells by utilizing different size columns available from the manufacturer 3) Proven ability to withstand extremely high use 4) Technology utilizes microscopic magnetic beads that will not adversely affect sorted populations 5) Compatibility with flow cytometry, PCR and other subsequent experiments and analytic methods of resulting populations without additional labor 6) Sorted populations are available for immediate analysis or experimentation 7) Capability of selecting for very rare cell populations (down to a frequency of 10-8) 8) Manufacturer carries a broad range of reagents allowing for positive or negative selection of specific murine cell profiles 9) Small overall footprint 10) User-friendly design and software. The following factors shall be used to evaluate offers: 1) price, 2) warranty, 3) capability to meet required specifications 4) training of staff 5) set up of equipment 6) Delivery time. Anticipated Date & Place of delivery September 29; NIH/NIAID, Maryland 20892; FOB-D. The following FAR provisions and clauses apply to this acquisition: FAR 52.212-1 Instructions to Offerors Commercial Items; FAR 52.212-2 Evaluation ?Commercial Items; FAR 52.212-3 Offerors Representations and Certifications Commercial Items; FAR 52.212-4, Contractor Terms and Conditions Commercial Items; FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. A completed copy of provisions FAR 52.212-3 Offerors Representations and Certifications Commercial Items must be included. Copies of the aforementioned clauses are available upon request by telephone to Ms. LaShawn Harris at (301) 496-2607. Offers must be submitted no later 5:00P.M. Eastern Daylight Time (EDT), August 11, 2003 to LaShawn Harris. For delivery through the postal service the address is NIH/NIAID/AMOB, 10401 Fernwood Drive, Suite 2NE70, Rm/2NE62B, MSC/4812, Bethesda, Maryland 20817-4812. Electronic submission will not be accepted. Request for information concerning this requirement are to be addressed to Ms. LaShawn Harris at (301) 496-2607. Collect calls will not be accepted. All responsible sources may submit an offer that will be considered by this agency.
- Place of Performance
- Address: National Institute of Health, Bethesda, Maryland
- Zip Code: 20817
- Country: USA
- Zip Code: 20817
- Record
- SN00382970-W 20030727/030726120530 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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