SOLICITATION NOTICE
D -- Resistance Management Model Development
- Notice Date
- 10/6/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Environmental Protection Agency, Ord Service Center, 26 West Martin Luther King Drive, Cincinnati, OH 45268
- ZIP Code
- 45268
- Solicitation Number
- RFQ-OH-04-00005
- Response Due
- 10/22/2003
- Archive Date
- 11/22/2003
- Point of Contact
- Point of Contact, Sandra Savage, Purchasing Agent, Phone (513) 487-2046
- E-Mail Address
-
Email your questions to U.S. Environmental Protection Agency
(savage.sandra@epa.gov)
- Description
- NAICS Code: 541511 EPA intends to issue a contract on a noncompetitive basis to Dr. Michael Caprio, Mississippi Statement University, for the development of a simulation program that will model the development of pest resistance to the new plant-incorporated protectant crops. The model will be based on the "Popgen" simulation program developed by Dr. Caprio. The requirement is for a robust and flexible predictive model that can simulate the impact of rare resistance events on a spatial scale and will offer a realistic evaluation of the evolution of pest resistance towards crops expressing one or more Bt toxins. The simulation model shall be hard-wired for pest biology, and shall have options for user-defined inputs around the properties of the PIP (dose, mode of action), the pest management landscape (i.e., alternate practices, other PIPs etc.), the uncertainties around the genetics of the resistance (SS RS, and RR fitness, cross-resistance), and the IRM plan itself (e.g., refuge, stack, mosaic, no plan). The predictive model shall include the following features: stochasticity, landscape spatiality, single and multiple toxins at the same or different dose levels, significant biotic and abiotic factors affecting the evolution of resistance(such as population dynamics, pest biology, density-dependent mortality, density-independent mortality, mating behavior, larvale and adult movement, immigration), genetics of resistance, initial resistance allele frequency, dominance, potential fitness costs, impact of cross-resistance, impact of alternate hosts, irrigation (or no irrigation), crop rotation, impact of agronomic practices, impact of alternate control tactics used in conjunction with Bt designed to control the evolution of Bt resistance (e.g., synthetic insecticides), and impact of various resistance mitigation strategies (e.g., refuge, crop rotation) on the evolution of resistance. The model will be required to evaluate different scenarios related to grower compliance with and adoption of the technology, and economics of various mitigation strategies. THIS IS NOT AN RFQ. NO SOLICITATION WILL BE ISSUED AS A RESULT OF THIS SYNOPSIS. Organizations that feel they can meet EPA's requirements must provide supporting documentation no later than 15 days after publication of this synopsis.
- Record
- SN00448387-W 20031008/031006213241 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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