SOLICITATION NOTICE
A -- Studies to Evaluate the Toxic and Carcinogenic Potential of Test Articles in Laboratory Animals for the National Toxicology Program (NTP)
- Notice Date
- 7/29/2004
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Research Contracts Branch, DERT P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- NIH-ES-04-12
- Response Due
- 10/14/2004
- Archive Date
- 10/29/2004
- Point of Contact
- Marilyn Whaley, Contract Officer, Phone 919-541-0416, Fax 919-541-2712, - Phyllis McKoy, Procurement Technician, Phone 919-541-7950, Fax 919-541-2712,
- E-Mail Address
-
whaley@niehs.nih.gov, mckoy2@niehs.nih.gov
- Description
- The NIEHS is soliciting offers for a contract to conduct short-term and long-term studies in laboratory animals to evaluate the toxic and carcinogenic potential of test articles by various routes of exposure. The project is designed to study diverse agents that may include: food additives; colorants or flavorings; pharmaceuticals and herbal remedies; herbicides, fungicides, and pesticides; ingredients found in soaps, lotions, perfumes, and cosmetics; in detergents and cleaners; in a wide variety of consumer products; used in manufacturing, or industrial settings, etc. The design of actual studies will vary as needed depending on the individual test agents, route(s) of exposure, and endpoints to be evaluated. Study duration may be from a few days up to 2-years or life time. Exposure may begin in utero or in young animals. The routes of administration may be dosed feed, dosed water, gavage, dermal, parenteral (intraperitoneal, subcutaneous, intravenous, intratrachael). These studies shall be conducted in accordance with the Specifications for the Conduct of Studies to Evaluate the Toxic and Carcinogenic Potential of Chemical, Biological and Physical Agents in Laboratory Animals for the National Toxicology Program. Offerors are advised that if they wish to receive a contract award they shall have a working laboratory conducting studies via the routes of administration identified above and outlined in the Statement of Work, in place by the date of proposal submission. The Principal Investigator, Toxicologist, Chemist, Veterinarian, Health and Safety Officer, and Quality Assurance Unit Officer shall be employees of the contract laboratory (i.e., not consultants or subcontractors). A working laboratory means that the facility has in place essential features necessary to conduct GLP toxicity/carcinogenicity studies of environmental agents involving large groups of rats and mice (e.g., environmentally controlled animal rooms, analytical laboratories, clinical laboratory, necropsy room, histology facility, etc.), and staff with appropriate expertise to expose, care for, and process large numbers of animals (e.g., chemists, toxicologists, pathologists, clinical pathologist, veterinarian, animal care technicians, prosectors, histologists, quality assessment group, etc.). The daily interaction and constant coordination of efforts needed amongst these discipline areas throughout the in-life portion of the studies makes it critical that they be physically and organizationally together. Award of two cost-reimbursement, completion type contracts on approximately May 1, 2005 with a ten year term on an open competition basis is contemplated as a result of this solicitation. The estimated level of effort is approximately 719,400 labor hours for the base contract and 169,955 for all options. The anticipated release date of the RFP is approximately August 16, 2004 with proposals due on approximately October 14, 2004. Interested organizations should request a copy of the solicitation by submitting a written request to the point of contact. All responsible sources may submit a proposal which shall be considered by the Agency. The electronic version of the Fed Biz Opps synopsis will be available on the Internet at: <http://www.niehs.nih.gov/dert/rcb/rfp.htm> . An electronic copy of the RFP (without the NTP Specifications) will be posted to this site on or about the RFP release date. This requirement is unrestricted. NAICS Code is 541710. Numbered Note 22 applies.
- Record
- SN00632793-W 20040731/040729211808 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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