MODIFICATION
A -- Tri-Service AIDS Clinical Consortium Data Analysis and Coordinating Center (TACC/DACC)
- Notice Date
- 1/20/2005
- Notice Type
- Modification
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institutes of Allergy and Infectious Diseases, Contract Management Program 6700 B Rockledge Room 3214 MSC7612, Bethesda, MD, 20892-7612
- ZIP Code
- 20892-7612
- Solicitation Number
- RFP-NIH-NIAID-DAIDS-06-06
- Response Due
- 4/21/2005
- Archive Date
- 5/6/2005
- Description
- ----- This Presolicitation Notice is being Modified to change the Response Date to 04/21/2005 and to change the intended contract award date to December 15, 2005. -----The mission of the Division of Acquired Immunodeficiency Syndrome (DAIDS), of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, is to help ensure an end to the HIV/AID epidemic by increasing basic knowledge of the pathogenesis and transmission of the human immunodeficiency virus or HIV supporting the development of therapies for HIV infection and its complications, and supporting the development of vaccines and other prevention strategies. The purpose of the planned acquisition is to establish a Data Analysis and Coordinating Center (DACC) for the Tri-Service AIDS Clinical Consortium (TACC), hereinafter referred to as the TACC DACC. The TACC is a multi-site, natural history study of HIV infection affecting primarily active duty U.S. military personnel and beneficiaries. The specific objective and scope of the TACC are to address the critical research questions on the natural and treated histories of HIV infection to minimize the adverse effects of HIV on the U.S. military community. The TACC collects medical, laboratory, and epidemiological data from the cohort to facilitate investigations of the biology and epidemiology of HIV transmission and factors affecting disease progression, the effectiveness of therapy, and HIV treatment outcomes. The services of a DACC are being sought to enhance the conduct of the TACC by providing expertise in epidemiology and biostatistical methods that optimize analyses of longitudinal HIV cohort data and fully utilize the network of TACC clinical sites, laboratories and specimen repositories. A sound methodological approach to the measurement of disease incidence, prevalence, and progression, based on currently used or new surrogate markers, shall be necessary in several TACC studies where key events, such as time of HIV seroconversion, are unknown. Additionally, the DACC will provide technical expertise in data collection, data management and quality assurance to produce a valid and reliable database for analyses. The DACC will participate in TACC conference calls, assist in reviews of proposed concepts, and will be expected to play a dynamic role in interacting with the TACC sites to guide the science of HIV research, and in helping to establish priorities and reasonable timelines for study activities, data analyses, and publications. Specifically, the Contractor shall carry out the following functions: 1) Establish and maintain collaborative relationships with the TACC study sites and the TACC Coordinating Team (CT); 2) Provide data cleaning, validation, and quality assurance for existing data and ongoing data collection activities; 3) Establish and maintain data security; 4) Support, train study staff, and facilitate management of cohort study operations; 5) Provide consultation in scientific study design and analytic strategies; 6) Initiate and conduct extensive cutting-edge data analyses for all retrospective, prospective, and collaborative research; 7) Consult in the design and analyses of data from clinical trials conducted within the cohort; 8) Provide data summaries for required scientific reports and presentations; 9) Document all data interactions, cleaning procedures, and analytic programs; and 10) Provide a transition of all data and documentation at the conclusion of the contract. The TACC DACC shall establish and administer efficient, reliable and responsive system for electronic communication among TACC clinical sites, NIAID Project Officer, and the TACC CT and for the collection, management, integration, quality assurance and reporting of study data. Offerors should demonstrate expertise in HIV longitudinal cohort study design, in the implementation and monitoring of longitudinal data collection, in statistical analyses of longitudinal data, in managerial ability to achieve delivery or performance requirements, and in the successful development and implementation of computerized databases and laboratory data management systems. It is anticipated that a single cost-reimbursement contract will be awarded for a 5-year period of performance beginning on or about December 15, 2005. This RFP will be available electronically on/about January 21, 2005, and may be accessed through the NIAID Contract Management Program (CMP) Home Page at http://www.niaid.nih.gov/contract and on FedBizOpps. Any reasonable offeror may submit a proposal that will be considered by the Government. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.
- Record
- SN00737414-W 20050122/050120211735 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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