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FBO DAILY ISSUE OF APRIL 24, 2005 FBO #1245
SOLICITATION NOTICE

68 -- Microarray Custom Chips

Notice Date
4/22/2005
 
Notice Type
Solicitation Notice
 
NAICS
541710 — Research and Development in the Physical, Engineering, and Life Sciences
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
 
ZIP Code
20817
 
Solicitation Number
Reference-Number-NOI-RML-5017
 
Response Due
5/9/2005
 
Archive Date
5/24/2005
 
Point of Contact
Jenny Lovitt, Purchasing Agent, Phone 406-363-9489, Fax 406-363-9376, - Lynda Kieres, Purchasing Agent, Phone 406-363-9210, Fax 406-363-9288,
 
E-Mail Address
jlovitt@niaid.nih.gov, lkieres@niaid.nih.gov
 
Description
This notice is a combined synopsis/solicitation, Notice of Intent. The Government intends to negotiate on a sole source basis with Affymetrix, for Custom Gene Chips, in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are not being requested and a written solicitation will not be issued. Submit offers on NOI-RML-5017. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-3 dated 4/11/05. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is not a Small Business Set-Aside. The North American Industry Classification System (NAICS) code for this procurement is 541710 and the small business size is 500. SCHEDULE: The Rocky Mountain Laboratories, (RML), performs basic research contributing to the development of diagnostic reagents, therapeutics and vaccines against human bacterial pathogens. Construction of an Affymetrix microarray custom chip containing oligonucleotide sequences representing six bacterial pathogen genomes was performed towards achieving those goals. The RML has a need to purchase approximately 1 (one) lot of custom chips from Affymetrix, lot size shall be 90 (ninety) chips. This chip is unique and specific to RML. The design and manufacturing process of this custom gene chip is wholly patented and owned by Affymetrix (USPNos. 5445934 and 5744305). The custom GeneChip was made by photolithography manufacturing technology (USPNos. 5424186, 5510270), developed solely by Affymetrix. The multi-genome GeneChip probe array must enable identification of 2-fold or greater levels of change in expression levels, and detection of as little as 1 mRNA transcript in a complex mixture of 100,000. The GeneChip probe array must contain multiple unique probes designed to be Perfect Match (PM), 25-mer oligonucleotide probe pairs, to represent each mRNA transcript (full length gene) tested, and multiple probes designed to be Mis-Match (MM), to enable calibration of non-specific hybridization data (USPNos.5527681). Additional control sequences (yeast and commensal) must also be available on the chip for hybridization control, and housekeeping gene analysis. The probe selection strategy for the multi-genome custom GeneChip probe array was based upon a probe design database (USPNos. 6188783) and was able to distinguish between highly homologous sequences and those of closely related gene families, strains, species and genus of bacteria. The multi-genome custom GeneChip probe array is housed in a fixed volume reaction chamber (USPNos. 5945334, 6140044) providing automated and consistent hybridization of samples to the array. RML processes the chips in Frederick, MD (NIAID) which contains: the Affymetrix GeneArray Scanner, Fluidics Station, 640 Hybridization Oven, Micro Array Suite/Data Mining Tool (USPNos. 5871928, 6040138, 6197506), MicroDB, and LIMS software database. No other photolithography-based chip, apart from those purchased from Affymetrix is compatible with the Affymetrix system in place at Frederick, MD. FOB Point shall be Destination, Hamilton, MT. Inside delivery shall be six (6) weeks after receipt of the order by Affymetrix. Delivery location is Rocky Mountain Laboratories, 903 S. 4th Street, Hamilton, MT. The following FAR provisions and clauses apply to this acquisition: (B)(1) By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the CCR database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation; 52.212-1 Instructions to Offerors Commercial Items; FAR52.212-2 Evaluation Commercial Items; FAR 52.212-4 Contract Terms and Conditions Commercial Items; FAR 52-212.5 Contract Terms and Conditions Required to Implement Statues or Executive Orders Commercial Items; FAR52.246-2 Inspection of Supplies-Fixed Price. By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall have posted their FAR 52.212-3 Offerors Representations and Certifications Commercial Items at website http://orca.bpn.gov. Award will be based on the capability of the item offered to meet the above stated salient characteristics, delivery, price and past performance. Offers may be mailed or faxed to the POC indicated above (Fax - 406-363-9376). Offers must be submitted not later than 4:30 PM (MDST), 05/09/05. Copies of the above-referenced clauses are available from http://www.arnet.gov/far/current/html/52_000_107.html or upon request, either by telephone or fax. All responsible sources may submit an offer that will be considered by this Agency. NOTE: THIS NOTICE WAS NOT POSTED TO WWW.FEDBIZOPPS.GOV ON THE DATE INDICATED IN THE NOTICE ITSELF (22-APR-2005); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Web Link
Link to FedBizOpps document.
(http://www.eps.gov/spg/HHS/NIH/AMOB/Reference-Number-NOI-RML-5017/listing.html)
 
Place of Performance
Address: Rocky Mountain Labs 903 South 4th Street Hamilton, MT
Zip Code: 59840
Country: US
 
Record
SN00794457-F 20050424/050422213331 (fbodaily.com)
 
Source
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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