MODIFICATION
A -- A SOLICITATION OF THE PUBLIC HEALTH SERVICE FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS
- Notice Date
- 8/3/2005
- Notice Type
- Modification
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, MD, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- PHS-2006-1
- Response Due
- 11/4/2005
- Archive Date
- 11/19/2005
- Point of Contact
- Office of Extramural Programs Office of Extramural Research, National Institutes of Health, Phone 301-435-2688, - Office of Extramural Programs Office of Extramural Research, National Institutes of Health, Phone 301-435-2688,
- E-Mail Address
-
none, none
- Description
- Innovative technologies and methodologies fuel progress in biomedical and behavioral research and represent an increasingly important area of the economy. The Small Business Innovation Research (SBIR) program provides support for research and development (R&D) of new or improved technologies and methodologies that have the potential to succeed as commercial products. The purpose of this notice is to (1) announce the issuance of the SOLICITATION OF THE PUBLIC HEALTH SERVICE FOR SMALL BUSINESS INNOVATION RESEARCH CONTRACT PROPOSALS (PHS 2006-1) with a due date of NOVEMBER 5, 2006 for receipt of SBIR CONTRACT proposals; and (2) inform the public about the opportunities that the SBIR program offers to small business concerns as well as to scientists at research institutions. The SBIR legislation requires the Public Health Service (PHS), Department of Health and Human Services, and certain other federal agencies to reserve 2.5 percent of their extramural research or R&D budgets for an SBIR program. The PHS SBIR set-aside requirement for FY 2004 is $571 million. The offeror organization must be a small business concern as defined by the Small Business Administration and described in the Solicitation, and the PRIMARY EMPLOYMENT of the principal investigator MUST be with the small business concern at the time of award and during the conduct of the proposed project. In accord with the intent of the SBIR program to increase private sector commercialization of innovations derived from federal R&D, scientists at research institutions can play an important role in an SBIR project by serving as consultants and/or subcontractors to the small business concern. Generally, one-third of the Phase I budget may be spent on consultant and/or subcontractual costs, and, generally, one-half of the Phase II budget may be spent on such costs. In this manner, a small business concern with limited expertise and/or research facilities may benefit from teaming with a Scientist(s)at a research institution; for the scientist(s)at a research institution, this team effort provides support for R&D not otherwise obtained. The SBIR program consists of the following three phases: PHASE I: The objective of this phase is to determine the scientific and technical merit and feasibility and potential for commercialization of the proposed research or R&D efforts and the quality of performance of the small business concern, before consideration of further federal support in Phase II. Generally, Phase I SBIR awards do not exceed $100,000 for direct costs, Facilities and Administrative (F&A) costs, and negotiated fixed fee for a period generally not to exceed six months. PHASE II: The objective of this phase is to continue the research or R&D efforts initiated in Phase I. Funding shall be based on the results of Phase I and the scientific and technical merit and commercial potential of the Phase II proposal. Only Phase I contractors are eligible to apply for Phase II funding, and Phase II proposals may be submitted upon the request of the Contracting Officer ONLY. (However, see "Fast-Track" Initiative below.) Generally, Phase II awards do not exceed $750,000 for direct costs, F&A costs, and negotiated fixed fee for a period generally not to exceed two years. That is, generally, a two-year Phase II project does not cost more than $750,000 for that project. Only one Phase II award may be made for any SBIR project. PHASE III: The objective of this phase is for the small business concern to pursue, with non-SBIR funds, the commercialization of the results of the research or R&D funded in Phases I and II. "FAST-TRACK" INITIATIVE: (Applicable only to proposals submitted to the National Institutes of Health [NIH] and only if an awarding component indicates it is accepting Fast Track proposals for a particular topic.) The Fast-Track initiative is an opportunity for small business concerns to submit both a Phase I and Phase II proposal for concurrent peer review. This initiative also has the potential to minimize any funding gap between Phase I and Phase II. Proposals must be prepared in accordance with Phase I and Phase II proposal preparation instructions. Following are the research topics contained in the SOLICITATION OF THE PUBLIC HEALTH SERVICE FOR SMALL BUSINESS INNOVATION RESEARCH CONTRACT PROPOSALS (PHS 2006-1) for the contract proposal RECEIPT DATE of NOVEMBER 4, 2005: NATIONAL INSTITUTES OF HEALTH National Cancer Institute (NCI) o 196 Antibody Array for Cancer Detection o 197 Early Detection Research Network Bioinformatics Research Program o 204 Plant Genomic Models for Establishing Physiological Relevance of Bioactive Components as Cancer Protectants o 205 Metabolomics for Early Cancer Detection o 206 Methods for Innovative Pharmaceutical Manufacturing and Quality Assurance o 207 Synthesis Modules for Radiopharmaceutical Production o 208 Targetry Systems for Production of Research Radionucleides o 215 Methods for the Purification Membrane Proteins and Macromolecular Complexes o 216 Development of Inhibitory Reagents for the Study of Protein Function o 217 Nanoparticle Biosensors for Recognition of Exposure and Risk Analysis in Cancer o 218 Development of Novel Methylation Assays for Cancer Detection o 219 Platform Biosensor Technologies for Point-of-care Cancer Diagnostics o 220 Chemical Optimization and Structure-Activity Relationship o 221 Oral Bioavailability Enhancement of Drug Candidates Using Innovative Excipients o 222 Investigation of the Production Parameters of Microbial Natural Products o 223 Synthesis and High-throughput Screening of an in vivo Cancer Molecular Agent o 224 Developing Diagnostically Aided Active Targeted Delivery Systems for Chemotherapeutic Agents o 225 Home Centered Coordinated Cancer Care System o 226 A Clinical Decision Support Tool to Promote Evidence-Based Screening and Intervention in Tobacco Users o 227 Quantum Dot Nanotechnology to Detect Oncogenic Human Papillomaviruses o 228 Quantum Dot Nanotechnology to Quantify Marker Expression in Breast Cancer National Institute on Drug Abuse (NIDA) o 064 Nanoscience-based Design of Therapies for Substance Abuse Treatment o 076 Development Of Science Literacy Materials Or Programs o 077 Development of Serious Games for Neuro-Rehabilitation of Drug-Induced Cognitive Deficiencies o 078 E-Health Applications of Empirically Supported Therapies in English and/or Spanish o 079 Development of State-of-the-Art Mechanisms for Epidemiological Research o 080 Training and Infrastructure Development for Community Coalitions o 081 Clinical Trials for Anti-addiction Medication Development o 082 Development of Novel Drug Delivery Systems for Treatment of Drug Addictions o 083 Create High Quality Feeder Layer Independent C57BL/6 Mouse ES Cells and Other Inbred ES Lines for High Through Put Gene Targeting o 084 Develop Methods for Stimulating International Research Collaborations National Institute of Mental Health (NIMH) o 044 Interactive Web-Based Networking Tool for Linking Services and Interventions Research Training and Education Programs o 051 Multi-Media Training and Education Materials for Cost-Effectiveness Analysis and/or Pharmaco-economics in Mental Health Services Research o 052 Interactive Tools for State Mental Health Agencies around the Implementation of Evidence-Based Practices o 053 Development/Adaptation of Tools and Monitoring Systems for the Implementation of Scientifically-Based Interventions and Engagement Strategies to Reduce Mental Health Problems o 056 Families as Research Partners: Development of Interactive Educational and Dissemination Modules to Train Family Members of Older Adults with Emotional or Behavioral Disorders about Mental Health Research Methods, Procedures, Data Analyses, and Interpretation National Heart, Lung, and Blood Institute (NHLBI) o 031 New Technology Development for Global Assay of Blood Coagulation o 033 Develop and Test a Diagnostic Tool for von Willebrand Disease o 034 Simultaneous Assessment of Physical Activity and Sleep Centers for Disease Control and Prevention (CDC) National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) o 022 Interoperable Electronic Health Record System o 023 Software Tool for Evaluating a Patient?s Risk for Developing Chronic Diseases and Recommending Lifestyle Changes o 024 Simplified Fingerprint Collection and Interpretation for Medical Risk Assessment National Center for HIV, STD and TB Prevention (NCHSTP) o 019 Development of Novel Genotyping Procedures for Mycobacterium Tuberculosis o 020 New Laboratory Tests for Tuberculosis and Detection of Drug Resistance o 021 Development of a Novel Information System for Remote TB Control and Prevention Programs o 022 Technology to Develop Handheld Amplification Test for Sexually Transmitted Infections o 023 Technology to Develop an Ambient Temperature Specimen Transport System o 024 System to Concentrate and Purify Nucleic Acids from Whole Blood o 025 A Delivery System for Patient-Delivered Partner Treatment for Sexually Transmitted Disease Control o 026 Technologies to Reduce Unsafe Injections and Sharps Injuries National Immunization Program (NIP) o 016 Develop Methods to Enhance Administration of Vaccines, Including Live Virus Vaccines, Through the Respiratory Tract o 019 Disposable-Cartridge Jet Injector Technology o 020 Development of Serologic Tests to Detect Immune Responses in Bordetella pertussis Infection o 021 Development of a Rapid, Point-of-Care Test for the Diagnosis of Current Pertussis Infection INQUIRIES Eligibility requirements, definitions, submission procedures, review considerations, contract proposal forms and instructions, and other pertinent information, including the "Fast-Track" Initiative, are contained in the SOLICITATION OF THE PUBLIC HEALTH SERVICE FOR SMALL BUSINESS INNOVATION RESEARCH CONTRACT PROPOSALS (PHS 2005-1) for the proposal receipt date of November 4, 2005. The PHS SBIR Contract Solicitation PHS 2006-1, including proposal forms, is available electronically through the National Institutes of Health's "Small Business Funding Opportunities" home page at http://grants.nih.gov/grants/funding/sbir.htm. See SBIR Phase I Contract Solicitation PHS 2006-1 (PDF [http://grants.nih.gov/grants/funding/SBIRContract/PHS2006-1.pdf] or MS Word [http://grants.nih.gov/grants/funding/SBIRContract/PHS2006-1.doc]). Be sure to use the appropriate CONTRACT PROPOSAL forms as they differ from the PHS 398 GRANT application forms. Note: The SBIR Phase I Contract Solicitation will only be available via electronic means. Potential offerors are encouraged to check the NIH SBIR/STTR home page for updates on the program. Any updates or corrections to the solicitation will be posted there. Contracting Officers Any small business concern that intends to submit an SBIR contract proposal under this Solicitation should provide the appropriate contracting officer(s) with early, written notice of its intent, giving its name, address, telephone, and topic number(s). If a topic is modified or canceled before this Solicitation closes, only those companies that have expressed such intent will be notified. NATIONAL INSTITUTES OF HEALTH (NIH) National Cancer Institute (NCI) Ms. Mary Landi-O?Leary Phone: (301) 435-3807 Fax: (301) 480-0309 Email: ml186r@nih.gov National Institute on Drug Abuse (NIDA) Ms. Nancy A. Hurd Phone: (301) 443-6677 Fax: (301) 443-7595 Email: nhurd@nida.nih.gov National Institute of Mental Health (NIMH) Mr. David Eskenazi Phone: (301) 443-2696 Fax: (301) 443-0501 Email: de5d@nih.gov National Heart, Lung, and Blood Institute (NHLBI) Mr. John Taylor Phone: (301) 435-0327 Fax: (301) 480-3338 E-mail: taylorjc@nhlbi.nih.gov CENTERS FOR DISEASE CONTROL AND PREVENTION National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) National Center for HIV, STD, and TB Prevention (NCHSTP) National Immunization Program (NIP) Mr. Curt Bryant Phone: (770) 488-2806 Fax: (770) 488-2828 Email: ckb9@cdc.gov Those interested in the PHS SBIR/STTR GRANT program may access electronically (http://grants.nih.gov/grants/funding/sbir.htm) the OMNIBUS SOLICITATION OF THE PUBLIC HEALTH SERVICE FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) and SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) GRANT APPLICATIONS (PHS 2005-2). There is one GRANT APPLICATION receipt date (December 1, 2005) remaining for calendar year 2005. To better understand the differences between grants and contracts, see http://grants.nih.gov/grants/funding/contracts_vs_grants.htm.
- Record
- SN00861219-W 20050805/050803211914 (fbodaily.com)
- Source
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