SOLICITATION NOTICE
A -- Reproductive Assessment in Rodents
- Notice Date
- 2/2/2006
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Research Contracts Branch, DERT P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- NIH-ES-06-02A
- Response Due
- 4/4/2006
- Archive Date
- 4/19/2006
- Small Business Set-Aside
- Total Small Business
- Description
- This Notice announces the intended release of solicitation number NIH-ES-06-02 previously published in the FedBizOpps Sources Sought Announcement dated December 9, 2005. The National Institute of Environmental Health Sciences (NIEHS) is soliciting proposals for testing of environmental agents, as identified by the National Toxicology Program (NTP), the Environmental Protection Agency (EPA) and other regulatory agencies. Environmental agents shall be tested for their potential reproductive toxicity in in-vivo rodent models. The contractor shall conduct multigeneration reproductive studies involving the testing of approximately 10 environmental agents per year, using the reproductive assessment by continuous breeding (RACB) protocol. The Contractor should have the following capabilities: animal facilities large enough to house 1500 rat cages with specific pathogen free (SPF) barrier conditions, capability to conduct Good Laboratory Practice (GLP) compliant studies, and prior experience conducting large-scale multigeneration reproductive studies in rats and mice. The contractor shall conduct histopathology evaluations on reproductive and other target organs, as well as crossover mating of animals. The laboratory and/or personnel should have prior experience in evaluating endocrine disruption endpoints and conducting dominant lethal tests. The Contractor shall comply with the following guidance/regulatory requirements: The Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) accreditation, NTP Health and Safety Minimum Requirements for Off-Site contractors, NTP Laboratory Animal Management Specifications, NTP Test Article Requirements for Toxicology Testing Laboratories, NTP Good Laboratory Practice Standards (GLPS) for Study Conduct, FDA GLP Regulations for Non-Clinical Laboratory Studies, and applicable Federal, State, and Local Laws. It is anticipated that one (1) cost reimbursement, completion type, award will be made, with an anticipated award date of September 30, 2006. The Government anticipates that the estimated level of effort for the project shall be approximately 35,500 direct labor hours per year. The period of performance is expected to be five (5) years with a possibility for the inclusion of "special studies" options. The anticipated release date of the RFP is February 17, 2006, with proposals due on or about April 4, 2006. Interested firms should telefax a request for RFP NIH-ES-06-02 to the attention of Ms. Juanita A. Campbell, Contract Specialist, at (301) 451-5597, or e-mail a request to campbellj@niehs.nih.gov. Electronic versions of the RFP will be available at http://www.niehs.nih.gov/dert/rcb/rfp.htm. See numbered notes 1 and 26.
- Record
- SN00978828-W 20060204/060202211820 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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