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FBO DAILY ISSUE OF FEBRUARY 25, 2006 FBO #1552
SOLICITATION NOTICE

A -- NIH Toolbox for Assessment of Neurological and Behavioral Function

Notice Date
2/23/2006
 
Notice Type
Solicitation Notice
 
NAICS
541720 — Research and Development in the Social Sciences and Humanities
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, Division of Research Acquisition, 6100 Executive Boulevard, Room 6E01, MSC 7540, Bethesda, MD, 20892-7540
 
ZIP Code
20892-7540
 
Solicitation Number
260-06-01
 
Point of Contact
Danielle Sweeney, Contracting Officer, Phone (301) 496-4487, Fax (301) 402-0178,
 
E-Mail Address
sweeneyd@od.nih.gov
 
Description
The National Institute on Aging (NIA), National Institutes of Health (NIH) has a requirement for the Development of the NIH Toolbox for Assessment of Neurological and Behavioral Function. The Contractor shall assist in the development of the NIH Toolbox for Assessment of Neurological and Behavioral Function. This toolbox is to provide investigators with a brief, but comprehensive, measurement tool for assessment of cognitive, emotional, sensory and motor function of participants in large cohort studies such as epidemiological studies, clinical studies, or clinical trials. The work under this contract shall include: 1) Development of a core set of tasks that will address the domains of cognitive, emotional, sensory, and motor function. 2) Integration of specific characteristics in the NIH Toolbox for Assessment of Neurological and Behavioral Function: Multidimensional - Should include multiple constructs within each of the domains of cognitive, motor, sensory and emotional function. Versatile - The assessment method should be capable of monitoring neurological and behavioral health status and function over time (as in longitudinal epidemiological studies) as well as evaluating effectiveness of interventions and treatments (as in clinical trials). Ceiling and floor effects should be considered. The measures should be modular and readily portable from one type of study design to another. Where psychometrically feasible, the method should incorporate ways to ‘crosswalk’ to existing and previous studies through the use of embedded benchmark items. This would eventually allow the mapping of a smaller set of test items back to a unifying latent construct where a common metric can be used across measures. Brief - All efforts should be taken to ensure low respondent burden. Methodologically sound - The measures should demonstrate validity and reliability. State-of-the-art - Development of the assessment method and measures should employ modern psychometric approaches to the measurement of latent dimensions, e.g., item response theory models and computer-adaptive testing, to the extent relevant. Diverse - The assessments should have known measurement properties across cultures and age ranges. English and Spanish versions should be developed and validated in culturally and geographically diverse groups. Dynamic - It will be strongly encouraged that the assessment method be dynamic, i.e., capable of being adapted over time in response to advances in science and/or advances in technology. Measures should be employed that are internally flexible, e.g., adaptive testing. The instrument should demonstrate sensitivity to change over time. The NIH is seeking an innovative approach to measurement that will be responsive to the needs of researchers in a variety of settings, with a particular emphasis on measuring outcomes in clinical trials and functional status in large cohort studies, e.g. epidemiological studies and longitudinal studies. Determining criteria for acceptability to the behavioral and neurological research communities prior to specific domain task development and evaluating the acceptability to researchers of the final instrument will be essential to successful completion of these goals. The tasks will be structured in two phases. Phase I will encompass qualitative research focusing on the identification of content area and the development of domain specific tasks. Phase II addresses the formal testing and refining of the final toolbox of tests. RFP 260-06-01 WILL BE AVAILABLE 15 DAYS AFTER ISSUANCE OF THIS SYNOPSIS AND WILL BE POSTED ON THIS WEBSITE. OFFERORS ARE RESPONSIBLE FOR ROUTINELY CHECKING THIS WEBSITE FOR ANY SOLICITATION AMENDMENTS THAT MAY BE ISSUED. NO INDIVIDUAL NOTIFICATION OF ANY AMENDMENTS WILL BE PROVIDED. Proposals will be due 45 days after issuance of the solicitation. All responsible sources may submit a proposal, which shall be considered by the Government. No collect calls will be accepted. NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (23-FEB-2006); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Web Link
Link to FedBizOpps document.
(http://www.fbo.gov/spg/HHS/NIH/OLAO-DRA/260-06-01/listing.html)
 
Record
SN00993865-F 20060225/060223214614 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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