SOLICITATION NOTICE
A -- Gulf South Hurricane Katrina Lung Health Study
- Notice Date
- 3/13/2006
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- NIH-ES-06-07
- Response Due
- 4/28/2006
- Archive Date
- 5/13/2006
- Point of Contact
- Velvet Torain, Contracting Officer, Phone 919-541-0400, Fax 919-541-2712, - Denise Tyre, Procurement Technician, Phone 919-316-4686, Fax 919-541-2712,
- E-Mail Address
-
torain@niehs.nih.gov, tyre@niehs.nih.gov
- Description
- The National Institute of Environmental Health Sciences, NIH, intends to negotiate a sole-source contract with Tulane University, Center for Bioenvironmental Research , 1430 Tulane Avenue, New Orleans, Louisiana to conduct a clinical epidemiology study of patients with chronic airway disease in the Gulf Coast region near New Orleans. The uniqueness of the gulf coast after Hurricane Katrina, in particular the high risk of exposure to mold and microbial toxins among the clean-up and construction workers and residents, presents an unprecedented opportunity to uncover the role of gene sequence variants and environmental exposures in the exacerbation of airway and other forms of lung disease. The degree to which mold concentrations, mold species, and mold toxins affect a person’s health is not clearly understood. Adequately addressing these questions will require prospective data be collected over approximately 30 months to define disease status in patients with chronic airway disease, and to define measures of exposure to mold and microbial toxins in biological samples of blood, urine and expired air, and from environmental samples collected in the human breathing zone and in indoor air in the household and workplace. Blood samples shall also be collected to identify specific genetic variants for disease exacerbation and progression in future studies. Some of the biological and environmental samples shall be analyzed by the contractor; the remainder of the samples will be stored at Tulane’s own laboratory or shipped to a designated laboratory of analysis. Specifically Tulane University shall conduct activities in the following areas: (1) Recruit and enroll approximately 1000 patients with chronic airway disease into the study. Provide and modify strategies for recruiting a diverse study group, including women, persons from lower socioeconomic backgrounds of particular ethnic or racial groups, older and hard-to-reach groups for study participation;(2) Conduct baseline and follow-up clinical assessments; analyze test results to determine airway disease status (exacerbating or stable). ; (3) Collect biological specimens of blood, urine, and expired air during clinical assessment; (4) Conduct environmental sampling of personal or indoor air in the study participants’ residence and/or workplace; (5) Administer a questionnaire to obtain information on reactive airway disease status and about potential confounding variables and effect modifiers; (6) Maintain a high response rate of 90% during the period following the baseline clinical assessment. Maintain a secured (patient protected) electronic database of study information for rapid retrieval and analysis; (7)Maintain a high level of community involvement and outreach;(8) Ensure data abstracting, editing, recording, tracking, and security. All protocols shall be the responsibility of the Contractor with approval from the Government before implementing. The period of performance will be for 30 months with a planned award date on or before September 29, 2006. It is anticipated that this project will require approximately 13,936 direct labor hours over 30 months. Sole Source Authority: 41 USC 253(c)(1), as set forth in FAR 6.302-1--Only One Responsible Source. Tulane University’s Center for Bioenvironmental Research have extensive capabilities in conducting complex respiratory epidemiology and clinical studies. Tulane investigators have extensive experience conducting both occupational and community-based health studies in this region, and have first-hand knowledge of the medical management infrastructure and level of operation of individual hospitals and clinics in the region. Tulane has a world-renowned expert, and recent appointee to the National Academy of Sciences, in the area of mold and microbial toxins, Dr. Joan Bennett. There are only a handful of such experts in the world, and having Dr. Bennett at Tulane is an advantage. Any other interested sources desiring consideration for this requirement must fully identify their interests and capabilities to the Contracting Officer listed above no later than 4:00 p.m. on April 28, 2006. This notice of intent is not a request for competitive proposals; no solicitation is available. See Numbered Note 22 and 26***** NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (13-MAR-2006); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
- Web Link
-
Link to FedBizOpps document.
(http://www.fbo.gov/spg/HHS/NIH/NIEHS/NIH-ES-06-07/listing.html)
- Record
- SN01005249-F 20060315/060313211924 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |