SOLICITATION NOTICE
66 -- SpectraMax M2
- Notice Date
- 3/24/2006
- Notice Type
- Solicitation Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
- ZIP Code
- 20852
- Solicitation Number
- Reference-Number-NCI-60048-NV
- Response Due
- 4/4/2006
- Archive Date
- 4/19/2006
- Description
- The National Cancer Institute (NCI), Center for Cancer Research (CCR), Molecular Pharmacology Section (MPS) plans to enter into a sole source procurement for a SpectraMax M2 microplate/cuvette reader from Molecular Devices, 1311 Orleans Drive, Sunnyvale, CA 94089. The MPS will be trading in its Molecular Devices Spectra Max Plus which it acquired in 2000 and no longer meets its needs. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees. This acquisition will be processed under FAR Part 12 ? Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.5 to use simplified procedures for commercial acquisitions. Molecular Devices is the only source known to the NCI researcher that has a microplate/cuvette reader that provides features that are required for their research and detailed below in their JOFOC. However, if any interested party believes it can perform requirement as detailed in the JOFOC they may submit a statement of capabilities. The statement of capabilities and any other furnished information must be in writing and must contain material in sufficient detail to allow the NCI researcher to determine if the party can perform this requirement. An original and one copy of the capability statement must be received in the contracting office by 1:00 pm EST, on April 4, 2006. Faxed and emailed capability statements are NOT authorized. All questions must be in writing and may be emailed to Debbie Moore at dm170b@nih.gov or faxed (301) 402-4513. It is the vendor?s responsibility to call (301) 402-4509 and verify that questions were received. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award from the NCI contractors must be registered in the Online Representations and Certifications Applications (ORCA) in order to receive an award. Please refer to http://orca.bpn.gov in order to register. In addition, contractors must be registered in the Central Contractor Registration (CCR) www.ccr.gov. No collect calls will be accepted. JUSTIFICATION FOR OTHER THAN FULL AND OPEN COMPETITION PART I ? BACKGROUND INFORMATION 1. Program Office: DHHS/NIH/NCI/CCR/MOB/Molecular Pharmacology Section 2. Project and Solicitation Molecular Devices ? SpectraMax M2 3, Purpose/Brief History: a. The Molecular Pharmacology Section, MOB, CCR, NCI is engaged in the understanding of the pharmacology of new anticancer agents. In addition, the Section is focused on the importance of genes associated with and that predict the risk of prostate cancer. b. Our laboratory performs experiments in molecular and cell biology on a daily basis. The SpectraMax M2 microplate spectrophotometer functions as both a fluorescence and absorbance reader making it highly useful for the routine assays that are carried out in the lab such as ELISAs, protein assays (Bradford), nucleic acid assays (A260 & PicoGreen), SNP genotyping, reporter assays using beta-galactosidase, cell proliferation and apoptosis assays as well as kinetic assays. The SpectraMax M2 is unique in its ability to perform all of these assays as well as its performance specifications which include: - A reading capacity for dual mode (Fluorescence & Absorbance), in 1cm cuvette port and in 6- to 384- well picroplates. - Dual monochromators for tunable fluorescence wavelength selection between 250nm and 850nm and tunable absorbance weavelength selection between 200nm and 1000nm. - Agitation and temperature control from 4C to 45C. - Reads up to four EX/EM wavelength pairs per microplate for multi-flourophore assay design. - Fixed fluorescence spectral bandwidth of 9nm for improved resolution between EX/EM components. Fixed absorbance bandwidth of less or equal to 4nm. - Full wavelength scanning capability across the entire spectral range for defining actual EX and EM maxima. Performs spectral scans in user-defined increments as small as 1nm, and then can select assay wavelengths for actual maxima. Increased sensitivity for assay by working at actual conditions rather than using literature references. - Automatic PMT setting to adjust the optimum voltage for each well sample concentration and normalize the raw data to show RFU values. Selectively rereads wells at the optimal PTM setting. - PathCheck ? sensor ? only sensor of its kind not affected by temperature, and requires no accessories to measure the pathlength of samples in all individual wells. - SoftPro Max data analysis and instrument control software that is usable on both Macintosh and Windows interfaces with a single program. Software has the ability to design custom assay protocols including instrument settings, plate templates, sample spreadsheet calculations, and graphs of all data. c. The supplier (Molecular Devices) will provide the SpectraMax M2 microplate fluorescence and absorbance spectrophotometer and SoftMaxPro software along with - Dell Notebook D505 bundle and lnitial Training Life Science d. There are no current plans for future procurements of this nature in subsequent fiscal years. PART II ? Facts and Reasons to Justify Other Than Full and Open Competition The sole source acquisition is justified under the statutory authority contained in U.S.C. 253(c)(1) and the following authority contemplated by FAR 13.106(b)(1). "When the supplies or services required by the agency are available from only one responsible source, ... and no other type of supplies or services will satisfy agency requirements, full and open competition need not be provided for." The Molecular Devices SpectraMax M2 is a unique instrument in that it enables the user to run a vast number of assays on the same machine from fluorescence to absorbance. It also allows the user to work with data results on a Windows or Apple platform. This is important in our lab as we use both. This instrument will allow the lab to complete current projects as well as work on new collaborations. Not acquiring this microplate reader could be detrimental to ongoing research.
- Record
- SN01014177-W 20060326/060324211927 (fbodaily.com)
- Source
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