MODIFICATION
99 -- Bench Top LC-MS-MS System
- Notice Date
- 6/6/2006
- Notice Type
- Modification
- Contracting Office
- Contracts Management Division 26 W. Martin Luther King Drive Cincinnati, OH 45268
- ZIP Code
- 45268
- Solicitation Number
- PR-CI-06-10735
- Response Due
- 6/26/2006
- Archive Date
- 7/1/2006
- Small Business Set-Aside
- N/A
- Description
- This synopsis is being reissued to adjust the response date so that it reflects the due date for responses to the just published solicitation. This synopsis is being provided to publish a requirement for the Mid-Continent Ecology Division (MED) of the Environmental Protection Agency?s (EPA) National Health and Environmental Effects Research Laboratory (NHEERL) in Duluth, Minnesota which has a requirement for a bench top liquid chromatograph-mass selective detector with a triple quadrupole mass analyzer (LC-MS-MS) system. This instrument will be delivered to and assembled at the U.S.EPA NHEERL/MED-Duluth laboratory where it will remain and be used for toxicological research. The LC-MS-MS instrument system must be capable of analyzing automated on-line microdialysis samples utilizing a microbore capable HPLC system. Hardware and software connectivity between instrument components and microdialysis injection equipment is a critical element. The HPLC sub-system is to consist of gradient capable mixing pumps at low flow, Peltier cooled autosampler, solvent degasser, sample enrichment capabilities, diode array detector, fluoresence detector and be able to accept external start/stop signal from external sample injection loop. The system should be able to be configured to be very tolerant of dissolved high solids and salts with low maintenance. No loss of sensitivity during runs of up to 96 hours and 200 injections are required. If special cones, torches, lenses, shields, spray chambers, nebulizers...etc are required to meet this requirement the seller must include these items in duplicate for this acquisition. The instrument system and cart must be mobile and be able to fit through the 40" wide doorways to allow for transport between labs. Automatic system startup, shutdown and optimization and computer controlled instrument tuning for optimum performance. The LC-MS-MS system must function from a single computer workstation. Connectivity between the MS-MS and HPLC must be complete as defined below: 1) Bidirectional communication between the MS-MS and the HPLC components is essential. If any LC component fails or the MS-MS faults, the system must not continue running and consuming samples scheduled to be analyzed. The total system should shut down or go into idle status without loss of previously injected sample data. Starting and stopping of system modules must be programmable events from the system software via the workstation. 2) All data generated from the LC-MS-MS must be saved in the event of a fatal system fault, up to completion of the previously injected sample during a sequenced run. 3) Real Time viewing of the LC-MS-MS data stream ( ie. chromatogram) must be possible. Alternatively, the ability to view a current chromatogram at a moment during its generation is acceptable. 4) The system must be capable of multi-tasking. During active LC-MS-MS operation and sample measurement it must be possible to process, view, reintegrate or transfer data files and view sequences previously saved. The data system must allow modification of the sequence being actively run to accommodate necessary changes in the sample scheduling. 5) Two copies or licenses to use the software at other non-instrument workstations for data manipulation shall be provided. System shall have CD ROM based presentations, delivered by application experts, on the following topics: Solution Chemistry, Sample Preparation, System Diagnostics, System Startup, De-convolution, System Calibration and LC/MS Fundamentals. These presentations are to include full video and audio features. System shall have on-line logbooks that provide date- and time-stamped records of runs, errors, and maintenance events. System shall allow for the creation of LC/MS spectral libraries. System shall allow for library searches based on both UV/VIS and mass spectral libraries. Installation: System shall include installation, basic instrument overview, four day operator?s training course, a 1 year warranty, and a 1 year telephone support contract provided in the list price of the product. A computer based training module and system maintenance procedures shall be provided on CD-ROM. Hard copies of instrument (i.e., HPLC-MS-MS) service manuals along with detailed schematics for all instrument parts and functions must be provided. These instrument manuals must cover instrument maintenance and troubleshooting procedures. The seller must include all associated hardware, regulators, gas lines, controllers, software, ... etc, in their submission so that the system will fully function on-site without the EPA purchasing additional items. HPLC-MS\MS instrument performance specifications must be guaranteed and demonstrated by on-site performance. The Vendor will provide the device under a turn-key installation to be accepted by the Government. A simplified low concentration method utilizing LC-MS/MS configured with an on-line microdialysis injector currently used by EPA MED-Duluth personnel will be set up, instrument connectivity established and multiple samples ran successfully by the vendor representative as part of confirmation of a successful installation. EPA MED-Duluth personnel will provide all solutions and column hardware necessary. Additional requirements and the specific specifications for each of the follow major components of this acquisition will be made available along with the solicitation: I) LC-MS-MS Requirements and Performance Specifications, II) HPLC Requirements, and III) Computer Requirements. The North American Industry Classification Code is 334516 with a small business size standard of 500 employees. A written solicitation, PR-CI-06-10735, is anticipated to be issued on Thursday 6/01/06. All responsible businesses may submit a quotation in response to the solicitation which shall be considered by the Agency. This procurement will be pursued using FAR Part 12 Commercial Acquisition methods and procedures. This notice of intent is not a request for competitive quotations. Additional information regarding the specific requirements and specifications for the components involved in this acquisition will be made available along with the solicitation. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. Products must meet all the minimum requirements of the Performance Work Statement (PWS) in order to be acceptable. In addition to price, it is anticipated that the following factors will be used to evaluate the offeror?s technical proposal: responsiveness to the PWS, previous experience, schedule and delivery. Award will be made to the offer that represents the Best Value. Contract type will be firm fixed price however the vendor may propose provisional progress payments tied to completed performance events with their proposal.
- Web Link
-
The Environmental Protection Agency
(http://www.epa.gov/oam/solicit)
- Record
- SN01063583-W 20060608/060606221218 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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