SOLICITATION NOTICE
68 -- MICROARRAY CUSTOM CHIPS
- Notice Date
- 6/8/2006
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
- ZIP Code
- 20817
- Solicitation Number
- Reference-Number-NOI-RML-6031
- Response Due
- 6/20/2006
- Archive Date
- 7/5/2006
- Description
- This notice is a combined synopsis/solicitation, Notice of Intent. The Government intends to negotiate on a sole source basis with Affymetrix, for Custom Gene Chips, in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are not being requested and a written solicitation will not be issued. Submit offers on NOI-RML-6031. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-09 dated 5/19/06. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is not a Small Business Set-Aside. The North American Industry Classification System (NAICS) code for this procurement is 541710 and the small business size is 500. SCHEDULE: The Rocky Mountain Laboratories, (RML), performs basic research contributing to the development of diagnostic reagents, therapeutics and vaccines against human bacterial pathogens. Construction of an Affymetrix microarray custom chip containing oligonucleotide sequences representing 4-5 bacterial genomes will assist towards achieving those goals. The RML has a need to construct a custom chip from the manufacturer that shall contain a diverse array of bacterial pathogen genomes. This chip shall be unique and specific to RML. No other chip of it?s kind shall exist. SCHEDULE: The contractor shall provide to RML services to produce a custom bacterial pathogen gene chip. This is a 6(six) to 8(eight) week, one time work effort, where the final product shall be a custom gene chip containing oligo pairs at high density, specific to 4-5 bacterial pathogen genomes. These chips shall be compatible with the Affymetrix fluidics and hybridization station and scanner. The design and manufacturing process of this custom gene chip is wholly patented and owned by Affymetrix. The chip shall be high density, at 106 per cm2 or greater (USPNos. 5445934 and 5744305). The custom GeneChip? shall be made by photolithography manufacturing technology (USPNos. 5424186, 5510270), developed solely by Affymetrix. The multi-genome GeneChip? probe array must enable identification of 2-fold or greater levels of change in expression levels, and detection of as little as 1 mRNA transcript in a complex mixture of 100,000. The GeneChip? probe array must contain multiple unique probes designed to be Perfect Match (PM), 25-mer oligonucleotide probe pairs, to represent each mRNA transcript (full length gene) tested, and multiple probes designed to be Mis-Match (MM), to enable calibration of non-specific hybridization data (USPNos.5527681). Additional control sequences (yeast and commensal) must also be available on the chip for hybridization control, and housekeeping gene analysis. The probe selection strategy for the multi-genome custom GeneChip? probe array shall be based upon a probe design database (USPNos. 6188783) and shall be able to distinguish between highly homologous sequences and those of closely related gene families, strains, species and genus of bacteria. The multi-genome custom GeneChip? probe array shall be housed in a fixed volume reaction chamber (USPNos. 5945334, 6140044) providing automated and consistent hybridization of samples to the array. No other photolithography-based chip, apart from those purchased from Affymetrix are compatible with the Affymetrix fluidics and hybridization system in place at RML. 135(one hundred thirty-five) chips shall be delivered to RML 2(two) months from award of the purchase order to the contractor. Purchase of additional chips shall be available on a Lot by Lot basis. FOB Point shall be Destination, Hamilton, MT. Delivery location is Rocky Mountain Laboratories, 903 S. 4th Street, Hamilton, MT. The following FAR provisions and clauses apply to this acquisition: (B)(1) By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the CCR database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation; 52.212-1 Instructions to Offerors Commercial Items; FAR52.212-2 Evaluation Commercial Items; FAR 52.212-4 Contract Terms and Conditions Commercial Items; FAR 52-212.5 Contract Terms and Conditions Required to Implement Statues or Executive Orders Commercial Items; By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall have posted their FAR 52.212-3 Offerors Representations and Certifications Commercial Items at website http://orca.bpn.gov. Award will be based on the capability of the item offered to meet the above stated salient characteristics, delivery, price and past performance. Offers may be mailed to Julienne Keiser at Rocky Mountain Laboratories, 903 S. 4th Street, Hamilton, Mt 59840, faxed to the POC indicated above (Fax - 406-363-9288), or e-mailed at (JKeiser@niaid.nih.gov). Offers must be submitted not later than 4:30 PM (MDST), 6/20/06. Copies of the above-referenced clauses are available from http://www.arnet.gov/far/current/html/52_000_107.html or upon request, either by telephone or fax. All responsible sources may submit an offer that will be considered by this Agency.
- Place of Performance
- Address: ROCKY MOUNTAIN LABORATORY, 903 S. 4TH STREET, HAMILTON, MT
- Zip Code: 59840
- Zip Code: 59840
- Record
- SN01065705-W 20060610/060608221912 (fbodaily.com)
- Source
-
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