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FBO DAILY ISSUE OF JUNE 23, 2006 FBO #1670
SOLICITATION NOTICE

A -- Develop of Novel Micro-Chip Surface Chemistries for Use in Surface Plasmon Resonance (SPR) Detection of Foodborne Bacterial and/or Viral Pathogens, and Toxins

Notice Date

6/21/2006
 

Notice Type

Solicitation Notice
 

NAICS

541710 — Research and Development in the Physical, Engineering, and Life Sciences
 

Contracting Office

Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, MD, 20857-0001
 

ZIP Code

20857-0001
 

Solicitation Number

FDA-SOL-06-00227-1016913
 

Response Due

8/7/2006
 

Archive Date

8/22/2006
 

Description

The Food and Drug Administration (FDA) intends to award a contract on a sole-source basis to the University of Washington. The main objective of this contract is to develop unique surface chemistries for Surface Plasmon Resonance (SPR) instrument micro-chips that will capture and present specific foodborne pathogens and toxins for SPR detection, and to perform multi-laboratory validation studies to demonstrate the reproducibility, accuracy and robustness of pathogen and toxin detection protocols in food. This contract will result in a five year IDIQ type contract with task orders. The objectives of the task orders include but are not limited to: (1) Develop and finalize SPR micro-chip surface chemistries for antibody-based capture and detection of small target analytes using the marine biotoxin tetrodotoxin (TTX) as the model analyte. (2)Demonstrate the enhanced performance of improved SPR surface chemistries for antibody-based capture and detection of the marine biotoxin tetrodotoxin (TTX) using a model detection protocol that demonstrates before-and-after improvements in detection performance. (3) Develop and finalize SPR micro-chip surface chemistries for antibody-based and/or DNA homology based capture and detection of the foodborne bacteria, viruses or toxins. The example analytes to be used should specifically include, a toxin, a virus (bird flu virus / norovirus / calici virus / rotavirus or comparable virus that causes foodborne illness), and/or a bacterium (E. coli OH157:H7 / Clostridium spp. / Shigella spp. / or similar bacterium that causes acute bacterial diarrhea or food poisoning). (4) Participate in a Multi-laboratory comparison of SPR methodology for the purpose of validating the reproducibility, accuracy and robustness of pathogen and toxin detection protocols in food. The proposed contract action is for R&D services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested parties may identify their interest and capability to respond to the requirements or submit proposals. This notice of intent is not a request for competitive proposals. However, all proposals received within forty five days after the date of publication of this synopsis will be considered by the Government. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Respondents will not be notified of the Government?s determination. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Responses may be submitted via email, to Alice Pag?n at Alice.Pagan@fda.hhs.gov and Elizabeth Osinski at Elizabeth.Osinski@fda.hhs.gov.
 

Place of Performance

Address: FDA/CFSAN, 5100 Paint Branch Pkwy, College Park, MD

Zip Code: 20740

Country: USA
 

Record

SN01074425-W 20060623/060621220257 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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