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FBO DAILY ISSUE OF JULY 07, 2006 FBO #1684
SOURCES SOUGHT

B -- Request for Information for DNA Synthsis

Notice Date
7/5/2006
 
Notice Type
Sources Sought
 
NAICS
541990 — All Other Professional, Scientific, and Technical Services
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 427, Room 12, Frederick, MD, 21702
 
ZIP Code
21702
 
Solicitation Number
RFISynthsis0706
 
Response Due
7/12/2006
 
Archive Date
7/27/2006
 
Description
REQUEST FOR INFORMATION SAIC-Frederick, Inc., on behalf of the National Cancer Institute?s Mammalian Gene Collection program, is requesting the following information from companies actively offering contract DNA synthesis: What would be the effect on the overall costs if two different clones for every cDNA ORF were synthesized, if the pairs of clones differ by a single base of the target? Specifically, for each assigned ORF, in addition to synthesizing one clone with its naturally occurring stop codon, what is the effect on cost in getting a second version of the construct which has the second base of the stop codon (of the same ORF) substituted with a ?C? (converting all three versions of stop codons to serine codons). Thus for the target gene, there would be two synthetic ORFs, each with and without a stop codon generated. What is the effect on the cost if 2 to 4 thousand cloned ORF sequences are targeted? Would the cost be impacted by the size of the construct or its GC content? The information above is requested in order to prepare an adequate Request For Proposal. Please email your responses to Jeanne Lewis, jlewis@ncifcrf.gov not later than 4:00 pm EST Wednesday, July 12.
 
Record
SN01082654-W 20060707/060705220305 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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