SOLICITATION NOTICE
66 -- Liquid Chromatograph Triple Quadropole Mass Spectrometer System (LC/MS/MS)
- Notice Date
- 7/25/2006
- Notice Type
- Solicitation Notice
- Contracting Office
- Contracts Management Division 26 W. Martin Luther King Drive Cincinnati, OH 45268
- ZIP Code
- 45268
- Solicitation Number
- PR-CI-06-11028
- Response Due
- 8/9/2006
- Archive Date
- 9/8/2006
- Small Business Set-Aside
- N/A
- Description
- The U.S. EPA National Risk Management Research Laboratory (NRMRL) located in Cincinnati, Ohio intends to negotiate on a sole source basis with Waters Corporation of Milford, Massachusetts for an Ultra Performance Liquid Chromatograph Triple Quadrupole Mass Spectrometer (LC/MS/MS) under the authority of FAR Part 13.106-1(b). The instrument will be used to assist researchers engaged in an active research program in the area of trace level determination of emerging contaminants (endocrine disrupting chemicals, perfluorinated surfactants, pharmaceuticals, and flame retardants) in complex environmental matrices (wastewater and animal wastes, surface and ground waters, and soils/sediments). The capabilities provided by the required system will allow EPA to (1) develop new analytical methods for finding and detecting emerging chemical threats to environmental systems, (2) maintain data integrity of another Waters Corporation instrument EPA is currently using to perform this research in the laboratory (Waters CapLC Q-TOF MS), and (3) refine existing methods for the compounds EPA already monitors by providing higher throughput (shortening analytical methods from weeks to hours to minutes) and more sensitive analysis. This requirement will utilize FAR Parts 12 and 13, Commercial and Simplified Acquisition Procedures. It has been determined that the Waters Corporation Acquity UPLC Quattro Premier XE MS is the only instrument able to meet the following minimum specifications: (1) Incorporation of two quadrupole mass analyzers (MS1 and MS2) each having a mass (m/z) range of 2-3000 amu. Because EPA is looking at oligomers and other high molecular weight species, the high range (up to 3000 amu) is required to perform routine analysis. (2) Capable of scanning up to 5000 amu/sec. Investing in high throughput analysis requires the fastest scanning ability to capture the sharpened peaks from the UPLC front end. Selecting an instrument with a slower scanning ability would cause reduced data quality. (3) Equipped with a dual APCI/ESI source with the ability to polarity switch between modes using an interscan delay of 20 ms. The ability to polarity switch between positive and negative modes with an interscan delay of 20 ms allows for enhanced data quality derived from each and every sample run. (4) Operation up to a pressure of 15,000 psi at 1ml/min, which enhances both the speed and sensitivity of the analysis and allows the EPA laboratory to use the latest small particle technology chromatographic columns. This technology provides enhanced separation at greater speeds for difficult to separate compounds in environmental matrices such as human and animal wastes. (5) Demonstrate nearly Gaussian peaks and a signal to noise ratio greater than or equal to 100:1 for a 2.5 pg on column injection of chloramphenicol while operating in negative ESI MRM with a 0.5 second dwell time over a 0 Da span. Several EPA projects involve analyzing compounds in negative ion mode. Market research indicates that the Waters Corporation instrument is the only vendor to list a negative ion mode spec in this sensitivity range. Having the negative ion mode spec ensures guaranteed performance of the system. THIS NOTICE IS NOT A REQUEST FOR QUOTATION. However, any firm believing itself capable of providing an Ultra Performance Liquid Chromatograph Triple Quadrupole Mass Spectrometer that meets the specifications identified above may submit technical documentation to establish their capability. Such documentation must be submitted to Scott Tharp, Contracting Officer, within 15 days of electronic posting of this notice. A determination not to compete the proposed requirement based upon responses received will normally be considered solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement or to proceed on a sole source basis. Documentation should be submitted in writing to Scott Tharp via Fax (513) 487-2107 or email Tharp.Scott@epa.gov. Telephone responses will not be honored.
- Web Link
-
The Environmental Protection Agency
(http://www.epa.gov/oam/solicit)
- Record
- SN01097669-W 20060727/060725221443 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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