SOLICITATION NOTICE
66 -- Instruments & Lab Equipment
- Notice Date
- 8/8/2006
- Notice Type
- Solicitation Notice
- NAICS
- 339111
— Laboratory Apparatus and Furniture Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- PPI60341
- Response Due
- 8/24/2006
- Archive Date
- 9/8/2006
- Description
- The National Institute of Environmental Health Sciences (NIEHS) intends to negotiate on a sole source basis with Barofold, Inc., 1376 Miners Drive, STE 101, Lafayette, CO 80026, pursuant to 41 U.S.C.253(c)(1)--Only one responsible source and no other supplies or services will satisfy agency requirements. Barofold is the only known source that can provide a high pressure process for refolding proteins in a form that will allow NIEHS researchers to pursue the experiments that the research requires. The role of the protein expression core facility is to help the NIEHS researchers with their protein expression need. Many eukaryote (human, mouse, etc) proteins express as insoluble aggregates in both E. coli and baculovirus systems. These insoluble aggregates represent a success for expression, but can not be used for most of the needs of NIEHS researchers. TheBarofold PreEMIT Trademark Instrument System provides a process that will allow NIEHS researchers to quickly and efficiently refold these aggregates into useful proteins. The Barofold technology represents a new method for refolding these proteins to enable researchers to refold the proteins quickly and in high concentration, something that no other known refolding approach can do. TheBarofold PreEMIT Trademark Instrument System includes training and 20 hours of technical/scientific consulting, HiPER-FOLD Starter Kit, HiPER-Fold Redox Screen Kit, HiPer-Fold Protein Solubililty Kit, HiPER-Fold Additive Screen Kit, and ProVENT Caissons. The associated U.S. Patents owed by Barold are: 6,489,45 (High Pressure Refolding of Protein Aggregates and Inclusion Bodies) and 7,064,192 (High Pressure Refolding of Protein Aggregates and Inclusion Bodies). Additional patents are pending for further applications of this technology and for the design use of ProVENT Caissons. Any firm believing itself capable of providing this requirement may respond by submitting a written narrative statement of capability within 15 days of date of notice to Paula Pier at the above address for consideration by the agency. Response must include detailed technical information and other technical literature demonstrating the ability to meet these requirements. Responses shall also include itemized pricing that is sufficient to make a determination that competition is feasible. If no affirmative responses are received within 15 days of this notice to determine whether a qualified source is more advantageous to the Government, an order will be placed with Barofold, Inc. The NAICS Code/Size is 339111/500EM. This purchase is to be processed using Simplified Acquisition Procedures in conjunction with FAR Part 12, Acquisition of Commercial Items and is not expected to exceed the Simplified Acquisition threshold of $100,000. There is no solicitation package available. For any questions regarding this announcement, please contact Paula Pier via email pierp@niehs.nih.gov.*****
- Record
- SN01108795-W 20060810/060808220432 (fbodaily.com)
- Source
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