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FBO DAILY ISSUE OF SEPTEMBER 01, 2006 FBO #1740
SOLICITATION NOTICE

A -- ToxCast Prioritization of Environmentally Relevant Chemicals 2

Notice Date
5/16/2006
 
Notice Type
Solicitation Notice
 
Contracting Office
Bid and Proposal Room, Ariel Rios Building (3802R) 1200 Pennsylvania Avenue, N.W. Washington, DC 20460
 
ZIP Code
20460
 
Solicitation Number
PR-HQ-06-14708
 
Response Due
7/1/2006
 
Point of Contact
JOHN J. NANARTOWICZ, Placement Contracting Officer, Phone: 202-564-4756, E-Mail: nanartowicz.john@epa.gov
 
E-Mail Address
JOHN J. NANARTOWICZ
(nanartowicz.john@epa.gov)
 
Small Business Set-Aside
N/A
 
Description
This solicitation is the second issued for the TOXCAST PROGRAM by the Headquarters Procurement Operations Division of the Office of Acquisition Management of the U.S. EPA. THE TWO REQUIREMENTS ADDRESSED IN THIS SOLICITATION WILL BE PROCURED AS FOLLOWS: FULL AND OPEN COMPETITIVE PROCEDURE for Performance Work Statement (PWS) P#2; and SMALL BUSINESS SET-ASIDE COMPETITIVE PROCEDURE for PWS P#6. THE APPLICABLE NAICS CODE for the SMALL BUSINESS SET-ASIDE IS 541710 WITH A SIZE STANDARD OF 500 EMPLOYEES!! BACKGROUND: The Environmental Protection Agency, Office of Research and Development established the National Center for Computational Toxicology (NCCT) in 2005 to research the utility of computational chemistry, high-throughput screening (HTS) and various toxicogenomic technologies for Agency use in chemical prioritization, quantitative risk assessment and biological modeling. As part of this, the NCCT is developing computational tools for interpreting data from these technologies to classify chemicals, predict toxicity, and prioritize limited testing resources towards chemicals and endpoints that present the greatest risk to human health and the environment. Thus a chemical prioritization research program, entitled ToxCast, is being initiated with the purpose of developing the ability to predict, or forecast toxicity. The proof-of-concept phase of ToxCast will focus upon chemicals with a rich toxicological database (e.g., registered pesticide actives), in order to provide an interpretive context. Following this proof-of-concept, the ToxCast program will move on to other environmental chemicals domains relevant to EPA. The ToxCast program will evaluate chemical properties and effects across a broad spectrum of information domains: physical-chemical properties, predicted biological activities based on existing structure-activity models, biochemical properties based on HTS assays, cell based phenotypic assays, and genomic and metabolomic analyses of cells. SCOPE: Much of the data in these various domains will be generated through a series of seven (7) integrated Performance Work Statements (PWS). The contracts that will be awarded from these PWS will be essential components of the ToxCast program over the next five years, providing data populating the various domains that can be interpretively linked to known or predicted toxicological properties of environmental chemicals. This Request for Proposals (RFP) (# PR-HQ-06-14708) will be soliciting proposals for two (2) of the seven (7) PWS that make up the laboratory services requirement of the ToxCast Program. Potential offerors and interested parties should visit the EPA website to review all documents that relate to the program and these procurements. The EPA website is at: http://www.epa.gov/oamhpod1/adm_placement/prhq0614395/prhq0614395.htm The two (2) performance work statements under this RFP will be procured using the following methods: FULL AND OPEN COMPETITION for P#2; SMALL BUSINESS SET-ASIDE for P#6. It should be noted that hard copies of the RFP will not be mailed out, but will be available for down-loading from the EPA website along with all associated and supporting documents. Email the Contracting Officer at "nanartowicz.john@epa.gov" to express your interest in this solicitation package. Please include in your e-mail your firms complete name and address for Source List purposes. Due to the anticipated large volume of interest, we will be unable to return phone calls or respond to e-mail inquiries for these procurements. You may be able to retrieve a copy of the RFP package on or about June 5, 2006. NOTE: THIS NOTICE MAY HAVE POSTED ON FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (16-MAY-2006). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 30-AUG-2006, BUT REAPPEARED IN THE FTP FEED FOR THIS POSTING DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Web Link
The Environmental Protection Agency
(http://www.fbo.gov/spg/EPA/OAM/HQ/PR-HQ-06-14708/listing.html)
 
Record
SN01130800-F 20060901/060830224244 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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