SOLICITATION NOTICE
B -- Defining Host and HPV Gene Expression Profiles
- Notice Date
- 9/1/2006
- Notice Type
- Solicitation Notice
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-60188-NG
- Response Due
- 9/18/2006
- Archive Date
- 10/3/2006
- Description
- The National Cancer Institute (NCI) Division of Cancer Epidemiology and Genetics (DCEG) plans to procure on a sole source basis, services regarding: Expanded Evaluation of Gene Expression in the Succeed Study: Defining Host and HPV Gene Expression Profiles by Specific Cervix Cell Populations and Disease Status, with the University of Wisconsin, 1525 Linden Drive, Madison WI 53706. The supplies and services herein are being procured in accordance with the simplified acquisition procedures as authorized by FAR Part 13. The North American Industry Classification System code is 541380 and the business size standard is $11M. The purpose of this requisition is to provide service for optimized laser capture microdissection in cervical tissue, RNA extraction and amplification, and conduct of the Affymetrix U133 plus 2.0 human expression array chip. The University of Wisconsin at Madison presently constructs an in-house HPV array chip that contains 70-mer oligonucleotide probes for all genes of all 37 sequenced mucosotropic HPV genotypes as well as a few selected host genes. The chip has been verified and optimized with various known samples including HPV-expressing keratinocyte cell lines (NIHS, W12, CaSKI), oral cancer-driven cell lines, and primary cancer tissue, detection of unintegrated HPB DNA and the ability to add additional probes as desired, such as spliced mRNA junctions. HPV chip is produced solely by the University of Wisconsin at Madison and the utilization of these assays is critical to the proposed analysis of SUCCEED specimens for host and viral expression, to expand the previous contract MQ-515642 where initial SUCCEED tissue specimens have been evaluated, it is imperative for study validity that the expansion be conducted within the same laboratory using the same assays. This notice is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Capability statements must be received in the contracting office by 1:00 PM EDT, on September 18, 2006. For further information please contact Malinda Holdcraft, Contract Specialist via electronic mail at holdcram@exchange.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. No faxed or emailed capability statements will be accepted. In order to receive an award, contractors must be registered in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA). Reference NCI-60188-NG.
- Place of Performance
- Address: Contractor location
- Zip Code: 53706
- Country: UNITED STATES
- Zip Code: 53706
- Record
- SN01132498-W 20060903/060901220546 (fbodaily.com)
- Source
-
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