SOURCES SOUGHT
A -- Clinical Coordinating Center for Epidemiologic Studies in Hispanic Populations
- Notice Date
- 4/11/2005
- Notice Type
- Sources Sought
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, MD, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-HC-06-01
- Response Due
- 4/26/2005
- Point of Contact
- Kristiane Cooper, Contract Specialist, Phone 301-435-0345, Fax 301-480-3430, - John Taylor, Chief, ECA Section, Phone (301) 435-0345, Fax (301) 480-3430,
- E-Mail Address
-
kh22k@nih.gov, jt31s@nih.gov
- Description
- The National Heart, Lung, and Blood Institute (NHLBI) is conducting a market survey to determine the availability and potential technical capability of small business firms as defined by NAICS Code 54170 to perform as a Clinical Coordinating Center. The overall objectives of this research are to utilize the prospective study design to identify risk factors playing a protective or harmful role for cardiovascular and lung disease and sleep disorders in Hispanic populations, and to determine the role of acculturation in the prevalence and development of these diseases. Longitudinal cohort studies in Hispanic populations will provide the data necessary to develop prevention programs for disease in the Hispanics as well as the entire US population. To achieve these objectives the study will identify four geographical areas in the US of persons of Hispanic origin with stable population and strong community structure and organization representing the major Hispanic groups in the U.S. (Mexican-American, Cuban, Puerto Rican, Central/South American). Each area will have a field center which will identify, sample and recruit up to 4000 persons of Hispanic origin from each of areas for participation in a longitudinal study of cardiovascular and lung diseases (up to 16,000 persons). The field centers will each conduct a detailed examination of these study participants including fasting blood draw, questionnaires, and other procedures and will conduct an annual contact, consisting of a brief questionnaire, of these persons following the initial examination. The field centers will also identify new coronary heart disease, stroke, heart failure, and chronic obstructive pulmonary disease (COPD) events that have occurred following the initial examination, will identify acute exacerbations of asthma requiring ER care or hospitalization, and will review and adjudicate medical information from hospital, physician and other records. Finally study investigators will develop innovative hypotheses, perform data analysis, and produce publications from this study; provide community education and feedback regarding information from the study itself; provide information to improve the health of the communities in general; provide training for minority investigators; and provide opportunities for ancillary studies funded by other mechanisms by establishing collaborations and publicizing the potential for these opportunities. Necessary functions of the Clinical Coordinating Center will include active participation in the development of the study protocol and pilot testing procedures; leadership in organizing and conducting the centralized training and certification of study personnel; design and implementation of data collection procedures; design, implementation and maintenance of quality control procedures including assessment of reproducibility, validity, bias and drift in laboratory measurements in this study with 4 field centers; design of forms (including informed consent documents), Manuals of Operation, data entry and recruitment tracking computer programs, data bases and web sites for use by all Centers participating in the study; generation and enhancement of applications of appropriate statistical methods of analysis and presentation of data collected during the study; leadership in manuscript writing and publication; and establishment and maintenance of subcontracts to laboratories and reading centers. Capability statements should demonstrate: 1) professional qualifications of scientific, managerial and technical personnel including medical, technical, statistical, computer, and administrative staff with relevant expertise in epidemiologic research; 2) the organizational flexibility to modify the labor mix to meet the changing demand on the resource; 3) evidence of prior administrative and scientific leadership as a multi-center epidemiology study coordinating center managing a study of this size (up to 16,000 participants); 4) evidence of leadership in first-authoring and publishing scientific papers in a collaborative study; 5) experience and expertise in design, implementation and maintenance of quality control procedures including assessment of reproducibility, validity, and bias and drift in laboratory measurements in large multi-center studies; 6) substantial experience pertinent to the development of protocols and management of a wide variety of large-scale multi-center epidemiology studies; 7) experience and expertise in the epidemiology of cardiovascular and lung diseases, and sleep disorders; 8) clinical expertise to determine appropriate levels for participant alerts and referrals, and actions required for participant safety; 9) experience in generation and enhancement of applications of appropriate statistical methods of analysis and interpretation of medical data; 10) access to a large capacity computer facility and networking to remote terminals, and experience in installing and maintaining such networks; 11) capability to subcontract to laboratories and reading centers; and 12) the firm?s status as a small business under NAICS Code 541710. This is not a Request for Proposal. The Government is not responsible for costs associated with preparing capability statements in response to this announcement. Three copies of the material requested above should be submitted within 15 calendar days from the date of this publication. NOTE: THIS NOTICE MAY HAVE POSTED ON FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (11-APR-2005). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 03-OCT-2006, BUT REAPPEARED IN THE FTP FEED FOR THIS POSTING DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
- Web Link
-
Link to FedBizOpps document.
(http://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-HC-06-01/listing.html)
- Record
- SN01160897-F 20061005/061003222217 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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