SOLICITATION NOTICE
Q -- GENOME-WIDE ASSOCIATION STUDY
- Notice Date
- 11/30/2006
- Notice Type
- Solicitation Notice
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Nat'l Institute of Diabetes, Digestive, & Kidney Diseases, 2 Democracy Plaza, Suite 700W 6707 Democracy Blvd., MSC 5455, Bethesda, MD, 20892-5455, UNITED STATES
- ZIP Code
- 00000
- Solicitation Number
- NIH-NIDDK-07-100
- Response Due
- 12/26/2006
- Archive Date
- 1/10/2007
- Description
- The National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has a requirement to purchase a Genome-Wide Association Study from Translational Genomics Research, 445 N 5th Street, Suite 600, Phoenix, AZ 85004. The Contractor shall provide genotyping for the Phoenix Epidemiology and Clinical Research Branch, NIDDK. Since 1965, members of the Gila River Indian Community have participated in a longitudinal diabetes study. The biennial research examinations are conducted at the NIH Clinic in the Gila River Indian Community. These examinations include testing for diabetes and its complications. DNA has been collected from peripheral blood samples in most participants been in the last 20 years. Previous analyses of family data, including a genome-wide linkage study, indicate a strong familial aggregation of diabetes in this community and the presumptive chromosomal locations of one or more diabetes-?susceptibility genes. Current technology now allows for much denser mapping of single nucleotide polymorphisms (SNPs) covering the entire genome than has been possible previously. Genotype DNA samples, to be provided by NIH from approximately 975 participants in the Gila River Indian Community study. Genotyping should include approximately 500,000 SNPs covering the entire human genome. Data will be provided to NlH in a computer-readable format. The NIH will provide samples of DNA extracted from peripheral blood lymphocytes or cultured cells from study participants. The Contractor shall propose the quantity of DNA required per sample. The Contractor shall propose the method for genotyping, including quality control measures, for approval by the NIH. It is estimated that approximately 40 quality control samples will be necessary. The Contractor will provide the NIH with a computer-readable data set containing genotype results for each SNP typed, identified by each individual DNA sample submitted. The Contractor shall specify, for NIH approval, the data base program or format for data transfer. All responsible businesses that are capable of providing the Government with the items that are listed above may request a copy of the Request for Quote (RFQ) in writing or by FAX to 301-480-8501 to the Contracting Office prior to the closing date of this notice. It is anticipated that RFQ NIH-NIDDK-07-100 will be available fifteen (15) days after the publication date of this synopsis. Receipt of quotations will be due ten (10) days after the release of the RFQ. The anticipated award date is December 26, 2006. Request for copies of the RFQ must be submitted to the National Institute of Diabetes and Digestive and Kidney Diseases, 6707 Democracy Boulevard, Two Democracy Plaza, Room 774B, Bethesda, MD 20817 or via email griffinv@mail.nih.gov to the Attention: V. Lynn Griffin. FAX quotations must contain offerors name, address, telephone number and fax number. FAX quotations will be accepted if dated and signed by an authorized company representative. All requests for quotations should have a valid email address.
- Record
- SN01188525-W 20061202/061130220236 (fbodaily.com)
- Source
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