SOLICITATION NOTICE
66 -- IVIS Imaging Systems Series 100
- Notice Date
- 1/26/2007
- Notice Type
- Solicitation Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852, UNITED STATES
- ZIP Code
- 00000
- Solicitation Number
- NCI-70025-NG
- Response Due
- 2/5/2007
- Archive Date
- 2/20/2007
- Description
- The National Cancer Institute (NCI) plans to enter in to a sole source procurement for the brand name Xenogen IVIS Imaging System Series 100 part number 37100; Fluorescence Option part number XFO-12; and Work Bench part number XWS-260; with Caliper Life Sciences/Xenogen, Inc. 68 Elm Street, Hopkinton, MA 01748. This acquisition will be conducted under the procedures for acquiring commercial items authorized in FAR Part 12 and under the authority to use simplified procedures for commercial requirements as provided in FAR 13.501. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. This notice is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. No faxed or emailed capability statements will be accepted. Contractor shall provide one (1) original and one (1) copy of the capability statement. Capability statements must be received in the contracting office by 1:00 PM EST, on February 5, 2007. All questions must be in writing and can be faxed or emailed to: Malinda Holdcraft, Contract Specialist via electronic mail at holdcram@exchange.nih.gov or fax 301-402-4513. It is the vendors responsibility to ensure all questions have been received in the contracting office. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA). Reference: NCI-70025-NG on all correspondence. JUSTIFICATION FOR OTHER THAN FULL AND OPEN COMPETITION: Part I: Background information and description of requirements: The technology from Xenogen, in vivo imaging, enables investigators to track cells and visualize and quantify light output from expressed genes within an intact model animal, in real-time. Specimens may be studied longitudinally during experimental disease without having to be terminated, thus specimens serve as their own controls and numbers used in research may be potentially reduced. The instrument enables multiple investigators to utilize or plan experiments aimed at understanding mechanisms of metastasis and cell tracking in vivo. Benefit The results of such studies, as mentioned above, are expected to yield new information regarding ways to interrupt, prevent and otherwise treat the spread of cancer. In addition, it is highly likely that the identification of novel biomarkers applicable to patient diagnostics will result. For example, preliminary studies are underway to correlate novel biomarkers from human ovarian cancer with the cancer burden, using optical imaging instrumentation. These are expected to permit the filing of intellectual property claims based upon research performed with this instrument. Ancillary benefits include longitudinal experiments to be conducted resulting in the potential to reduce the number of research animals needed for such studies. Part II: Facts and Reasons to Justify Other than Full and Open Competition: Statutory Authority: 13.106-1 (b) and 13.501-(a)(1) (b) Soliciting from a single source. (1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, or industrial mobilization). (2) For sole source acquisitions of commercial items in excess of the simplified acquisition threshold conducted pursuant to subpart 13.5, the requirements at 13.501(a) apply. Justification: It is essential particularly for ongoing studies that the new imaging system be compatible with the current system in use, the IVIS Imaging System 100 Series. Salient characteristics required of instrumentation Imaging System Imaging chamber must be capable of imaging 5 mice simultaneously Imaging chamber external dimensions not to exceed 49 x 72 x 105 cm (W x D x H)- Due to housing space limits Heated sample stage: ambient up 40 degree C, controllable at 1 degree C increments at most Cryogenic refrigeration unit System calibrated against publicly recognized standards Gas anesthesia inlet and outlet ports for connection with gas anesthesia machine Imaging System Software/Hardware Acquisition software any provided that it is compatible with Living Image software version 2.20 and/or IgorPro 4.06A as well as newer versions including most recent release (to permit analysis of existing data sets), must also be capable of running on both Windows and Mac platforms Analysis software ? any provided that it is compatible with Living Image software version 2.20 and or IgorPro 4.06A as well as newer versions including most recent release (to permit analysis of existing data sets), must also be capable of running on both Windows and Mac platforms High performance acquisition computer and high resolution 20 inch flat-screen monitor Automated lens and stage positioning controlled via software Cooled CCD Camera Operating temperature, nominal minus 90 degree C CCD Size 26 X 26 mm Back-thinned, back-illuminated Grade 1 CCD 50 mm f 0.95 lens Field of view should be 10cm X 10cm to 25cm X 25cm Fluorescence Module Uniform sample illumination Autofluorescence background subtraction capability to minimize background signal Low autofluorescence fiber bundles Must be able to maintain integrity of light signal data per animal imaged Must include filter sets for the following fluorochromes: GTP, eGFP, FITC, DsRed, CellTracker Orange, Cy5.5, Alexa fluor 660 and 680, Indocyanine Green. Workstation to hold instrumentation: Workspace dimensions should be approximately 60in X 31in (L X W) in order to fit instrument and housing space Low maintenance surface and adequate to hold all necessary instrument components including keyboard Casters with locks, so instrument can easily be moved This in vivo optical imaging instrument is capable of luminescence and fluorescence detection. Xenogen Caliper Life Science is the only source known to the NCI that manufacturers this instrument that provides the salient characteristics required by the NCI research community.
- Place of Performance
- Address: Bethesda, MD
- Zip Code: 20892
- Country: UNITED STATES
- Zip Code: 20892
- Record
- SN01219835-W 20070128/070126220351 (fbodaily.com)
- Source
-
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