SOLICITATION NOTICE
B -- Sequencing
- Notice Date
- 9/14/2007
- Notice Type
- Solicitation Notice
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, MD, 20892-7902, UNITED STATES
- ZIP Code
- 00000
- Solicitation Number
- NHLBI-PB-HG-2007-266-KLW
- Response Due
- 9/28/2007
- Archive Date
- 10/13/2007
- Description
- This is a combined synopsis/solicitation for commercial items, prepared in accordance with the format of FAR 12.6, as supplemented with additional information included in this notice. This notice constitutes a combined synopsis/solicitation, and a separate written solicitation will not be issued. This solicitation is a Request for Quotation (RFQ). The reference solicitation number is NHLBI - PB-HG-2007-266-KLW This acquisition is in accordance with the simplified acquisition procedure authorized in FAR Part 13, and as a result, a purchase order will include all applicable provisions and clauses in effect through the Federal Acquisitions Circular 05-19. The total contracted dollar amount, including options will not exceed $5 Million. This requirement is being conducted on a non-competitive sole source basis and is classified under the North American Industry Classification System (NAICS) code applicable to this requirement as 334516 and the business size standard is 500 employees. The Government?s anticipated delivery date is sixty (60) calendar days after contract award. The delivery point is the National Institutes of Health, National Human Genome Research Institute (NHGRI), Bethesda, Maryland. Market research conducted by the Government has determined that Genetic Analysis Systems are manufactured in sufficient quantities by at least three (3) manufacturers which confirm the commercial market. The National Institutes of Health (NIH), National Heart Lung and Blood Institute (NHLBI), office of Acquisitions (OA) for the National Human Genome Research Institute (NHGRI), intend to award a single fixed priced purchase order to perform PCR Amplification and DNA Sequencing from 10 plates (96-well) of DNA for 10 amplicons of 400-600bp in size. This vendor will also can provide gDNA from zebrafish, store the gDNA for a period of one year and provide one direction sequencing. The period of performance will be for 12 months beginning September 2007 through September 2008. The vendor will perform an initial qualitative and quantitative assessment of isolated genomic samples by inspection on agarose gel and/or optical density. Sequencing primers will be designed as needed so as to allow for sufficient overlap in individual sequencing reads - when appropriate, primers used PCR may also be used for sequencing. Florescent dye-terminator chemistry will be used for bi-directional DNA sequencing, and sequencing delineation will be performed by automated ABI Prism 3730xl DNA sequencers , which give >650bp Q20/Phred20 read lengths. Description: The Vendor should be able to meet the pass/fail criteria as listed below: PASSING SEQUENCING READS ? Any read yielding at least PHRED20 base pairs, except in the case of shorter templates like PCR products. ? Any read that prematurely terminated due to anyone of the following difficult template types, which generate <200 PHRED20 base pairs: 1) Homopolymeric region (PolyN) 2) Repetitive regions (PolyTG) 3) GC rich templates and 2̊ structures ? A double insert/product producing ambiguous or ?N? bas calls throughout the reaction (called MIXED) FAILED SEQUENCING READS: ? Reads of insufficient intensity to provide full length sequence ?? 200 PHRED20 base pairs ? Reads consisting of largely undefined base calls denoted as ?N? The sole source determination is based upon the fact that this vendor offers each element on a consistent basis with a high degree of accuracy and speed. Changing vendors at this time would jeopardize the investments already made by the Government Remaining with this vendor would maintain the continuity of ongoing research being conducted in various studies and will provide the best value to the government. The provisions of FAR Clause 52.212-1, Instructions to Offerors-Commercial Item is applicable to this acquisition. The provisions of FAR Clause 52.212-2, Evaluation - Commercial Items is applicable to this acquisition. The purchase order award will be made to the Offeror whose product meets the Government?s minimum performance specifications, functional specifications, and delivery date. A best buy analysis will be performed taking into consideration price, shipping points, technical specifications, special features, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, environmental and energy efficiency considerations, delivery terms, and past performance. In addition to a price quote, the Offeror must submit descriptive literature of the product proposed, a commercial price list, warranty provisions, and any other information the Offeror considers relevant to the Government?s evaluation of the product proposed. The Government intends to evaluate the quotes and award the purchase order without discussion with Offerors. Therefore, the initial offer should contain the Offerors best terms, for a technical price standpoint. However the Government reserves the right to conduct discussions, request product samples or demonstrations, if later determined by the Contracting Officer to be necessary. The Government may reject any and all offers if such action is deemed necessary. The Government may also waive informalities and minor irregularities in the offers received. The Offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. The addendum to FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items, is as follows: The offeror must include in its quote, the unit price, the list price, installation charges, shipping and handling cost, the delivery date, prompt payment discount terms, the F.O.B. point (Destination or Origin), and provide descriptive literature inclusive of specifications as part of the quotation. The DUN and Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the business size. The offeror must be registered in the Government?s Central Contractor Registry (CCR) System, which is available at www.ccr.gov. The FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - commercial Items - Deviation for Simplified Acquisitions, applies to this acquisition. The following FAR clauses cited are applicable to this acquisition: (1) 52.222-26, Equal Opportunity (E.O. 11246). (2) 52.222-35, Affirmative Action for Disabled and Vietnam Era Veterans (38 U.S.C. 4212). (3) 52.222-36, Affirmative Action for Handicapped Workers (29 U.S.C. 793) (4) 52.222-37 Employment Reports on Special Disabled Veterans and Veterans of the Vietnam Era (38 U.S.C. 4212) (5) 52.225-3, Buy American Act-Supplies (41 U.S.C. 10). (6) (I) 52.225-21, Buy American Act-North American Free Trade Agreement Implementation Act - Balance of Payments Program (41 U.S.C. 10, Pub. L. 103-187). (6) (ii) Alternate I of 52.225-21. (7) 52.239-1 Privacy or Security Safeguards (5 U.S.C. 552a). There are no numbered notes applicable to this notice. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct future competitive procurement. Inquiries to this announcement, referencing solicitation number NHLBI-PB-HG-2007-266-KLW may be submitted by mail to the National Heart Lung, and Blood Institute, Office of Acquisitions, Procurement Branch, 6701 Rockledge Drive, Suite 6042, Bethesda, MD 20892-7902, Attention: Kesha Williams, Contract Specialist, or by fax transmission to (301) 480-3345. Responses may be submitted electronically to williamk@nhlbi.nih.gov or hawkinsd@nhlbi.nih.gov. Responses will only be accepted if dated and signed by an authorized company representative. All responsible sources may submit a response, which if timely received, shall be considered by the agency.
- Place of Performance
- Address: Bethesda, MD
- Zip Code: 20892-0001
- Country: UNITED STATES
- Zip Code: 20892-0001
- Record
- SN01406959-W 20070916/070915193406 (fbodaily.com)
- Source
-
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