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FBO DAILY ISSUE OF APRIL 09, 2008 FBO #2326
MODIFICATION

A -- NIMH Toxicological Evaluation of Novel Ligands Program

Notice Date
4/7/2008
 
Notice Type
Modification/Amendment/Cancel
 
NAICS
541712 — Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute on Mental Health, Contracts Management Branch 6001 Executive Blvd, Rm 8154, MSC 9661, Bethesda, MD, 20892-9661, UNITED STATES
 
ZIP Code
20892-9661
 
Solicitation Number
NIMH-08-DN-00011
 
Response Due
5/22/2008 5:00:00 PM
 
Archive Date
6/14/2008
 
Point of Contact
Mark Lohrmann, Contracting Officer, Phone 301-443-8886, - Bruce Anderson, Contracting Officer, Phone 301-443-2234, Fax 301-443-0501
 
E-Mail Address
lohrmannm@mail.nih.gov, ba9i@nih.gov
 
Description
The National Institute of Mental Health (NIMH) proposes to issue a Request for Proposals (RFP) No. NIMH-08-DN-00011 entitled "NIMH Toxicological Evaluation of Novel Ligands Program" under Full and Open Competition. The objective of resultant contract is to provide assessment of promising, target-selective ligands for PET, SPECT, and MRI imaging in humans, as well as limited assessment of novel psychoactive agents for clinical research and as potential therapeutics. Toxicology and safety data generated by the program are used to support Investigational New Drug (IND) applications to the Food and Drug Administration, or for Radioactive Drug Research Committee (RDRC) evaluation of a compound for human studies. Services to be provided under this program fall into four general areas: 1) analytical chemistry; 2) pharmacokinetics and bioavailability; 3) preliminary safety assessment; and 4) IND-directed toxicity assessments, including safety pharmacology. A three (3) year base contract with two (2), one (1) year options is contemplated. Plans are to award a contract by Sept 16, 2008. RFP No. NIMH-08-DN-00011 will be available on or about March 31, 2008 and the receipt date of proposals on or about May 30, 2008. The RFP may be accessed through http://www.fedbizopps.gov. Please note that the RFP for this requirement will include the Statement of Work, Deliverables, and Reporting Requirements, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. All responsible sources are encouraged to submit a proposal that will be considered by the NIMH. This advertisement does not commit the Government to award a contract. Please contact Mark Lohrmann, Contracting Officer at 301-443-8886 or lohrmannm@mail.nih.gov for further information.
 
Web Link
FedBizOpps Complete View
(https://www.fbo.gov/?s=opportunity&mode=form&id=cb4212fdd698a2084ab937c6bbb87b6d&tab=core&_cview=1)
 
Place of Performance
Address: NIMH R&D Contracts Management Branch6001 Executive Blvd, Rm 8154
Zip Code: Rockville, MD 20852
 
Record
SN01548296-W 20080409/080407215301-11c727c712dbb356e38365cd4a4e9fd1 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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