MODIFICATION
B -- Genetic Modification of Orange Tissues
- Notice Date
- 4/16/2008
- Notice Type
- Modification/Amendment/Cancel
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Agriculture, Animal and Plant Health Inspection Service, Administrative Services Division/Contracting, 100 North 6TH Street, Butler Square 5TH Floor, Minneapolis, Minnesota, 55403
- ZIP Code
- 55403
- Solicitation Number
- AG-6395-S-08-0059
- Response Due
- 4/24/2008 3:00:00 PM
- Point of Contact
- Nathan Johnson,,
- E-Mail Address
-
nathan.d.johnson@aphis.usda.gov
- Description
- Background The United States Department of Agriculture - Center for Plant Health Science & Technology (CPHST), is the scientific support agency of the Animal Plant Health Inspection Service, Plant Protection and Quarantine division. Plant Protection and Quarantine is responsible for safeguarding American agriculture from exotic pests and diseases and to provide response to incursions by eradication or containment. The high consequence exotic Citrus Greening pathogen, Candidatus Liberibacter asiaticus, was discovered in Florida 2005 and is now established throughout the major citrus growing regions of the state. Through the Citrus Health Response Plan, CPHST leads the effort to limit spread of this pathogen within Florida and to other citrus growing states where the pathogen is not present. There is no known source of viable resistance in Citrus species to Citrus Greening, and pesticides to the pathogen or to its psyllid vector is not effective in disease prevention. Citrus growing regions that have high prevalence of Citrus Greening become unproductive after a few years and this is anticipated to occur in Florida as disease prevalence increases. The future viability of the Florida citrus industry is dependent on finding a suitable means of production in the presence of the Citrus Greening Pathogen. It is imperative that a durable means of growing citrus that remains productive long enough for sustainable harvest be found. At this time, the development of resistant citrus germplasm through genetic engineering provides the most likely means of achieving this goal. Objective To produce within an 18 month window mature Valencia and Hamlin orange tissue germplasm transformed (genetically modified) to express an array of genes designed to impede growth of pathogenic bacteria specifically to provide demonstrated resistance to the Citrus Greening pathogen present in Florida commercial citrus groves. Qualifications At minimum a qualified scientific laboratory will meet the following qualifications: -Experience at transformation of a variety of plant hosts with suitable ‘freedom-to-operate’ for engineering technologies for Citrus species oDevelopment of transformation technologies of physiologically mature Citrus -Demonstrated ability to manipulate genes with antimicrobial properties: oSuitable ‘freedom-to-operate’ a variety of genes with demonstrated antimicrobial activities oDemonstration of experience and data that quantify parameters of antimicrobial efficacy of system oAbility to test and identify high resistance to Citrus Greening pathogen in Citrus hosts -Facilities suitable for Select Agent research and regulatory permits in place for experimentation with Citrus Greening pathogen Candidatus Liberibacter asiaticus Solicitation Availability The solicitation should be available on or about 24 April 2008 with an estimated proposal due date 20 days after solicitation posting.
- Web Link
-
FedBizOpps Complete View
(https://www.fbo.gov/?s=opportunity&mode=form&id=d0ddc6249026953038b5de3231296a68&tab=core&_cview=1)
- Record
- SN01555373-W 20080418/080416220534-d0ddc6249026953038b5de3231296a68 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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