SOLICITATION NOTICE
B -- Measuring Genomic Methylation in Leukocyte DNA
- Notice Date
- 5/9/2008
- Notice Type
- Presolicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-80074-NG
- Point of Contact
- Malinda L Holdcraft,, Phone: (301) 402-4509, Caren N Rasmussen,, Phone: (301) 402-4509
- E-Mail Address
-
holdcram@exchange.nih.gov, cr214i@nih.gov
- Small Business Set-Aside
- N/A
- Description
- The National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG), plans to procure on a sole source basis with Tufts University; Vitamins and Carcinogenesis Laboratory; 711 Washington Street; Boston, MA 02111 for measuring genomic methylation in leukocyte DNA for the association with lymphoma in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO). The supplies and services herein are being procured in accordance with the simplified acquisition procedures as authorized by FAR Part 13. The North American Industry Classification System code is 541380 and the business size standard is $11M. The purpose of this requirement is to determine whether the levels of a molecular marker, namely genomic methylation of leukocyte DNA are lower among people who later develop lymphoid cancers than people who do not. NCI researchers have identified 320 cases and 320 controls in the PLCO Cancer Screening Trial cohort. It is of special interest to study lymphoma risk using this marker in leukocytes, considering leukocytes include lymphocytes, the target tissue of the malignancy. The NCI requires the quantification of the methylcytosine content in the whole genomic DNA. Period of Performance shall be twelve (12) months from date of award. Only one award will be made as a result of this solicitation. Tufts University, more specifically, the Vitamins and Carcinogenesis Laboratory, is the only source known to the NCI that are leading experts in the research of global DNA methylation. They are the only laboratory known that is suitable for reliable high-quantity assays of epidemiologic samples for global methylation status. In addition, Tufts University, Vitamins and Carcinogenesis Laboratory, can provide complete whole genomic methylation, is the only source of this measurement, and has established and refined the procedure. Changing variables at this time would be detrimental to the current research, experiments, and trials being performed within the NCI. This notice is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party has the unique capabilities, resources and personnel to perform the requirement. Capability statements must be received in the contracting office by 11:00 AM ET, on May 23, 2008. For further information please contact Malinda Holdcraft, Contract Specialist via electronic mail at holdcram@exchange.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. No faxed or emailed capability statements will be accepted. In order to receive an award, contractors must be registered in and have valid certifications in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA). Reference NCI-80074-NG on all correspondence.
- Web Link
-
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- Record
- SN01570611-W 20080511/080509220753-09e840ce557cd59f87c04f328e241a0b (fbodaily.com)
- Source
-
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