SOLICITATION NOTICE
66 -- CRYOTRANSFER SINGLE TILT HOLDER
- Notice Date
- 7/29/2008
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-PB-AR-2008-194-RCO
- Archive Date
- 8/27/2008
- Point of Contact
- Rosie C Owens,, Phone: (301) 435-7920, Kathleen Marsden,, Phone: 301.435.0364
- E-Mail Address
-
rowens@mail.nih.gov, marsdenk@nhlbi.nih.gov
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NHLBI-PB-(AR)-2008-194-RCO and is issued as a Request for Quotation (RFQ). The solicitation will include all applicable provisions and clauses in effect through Federal Acquisition Circular 05-26 (as of 06/12/2008). The North American Industry Classification (NAICS) Code is 334516, and the business size standard is 500. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. However, this solicitation is set aside for small businesses. It is the intent of the National Heart, Lung, and Blood Institute’s (NHLBI) Consolidated Operations Acquisition Centers (COAC) on behalf of National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to procure the services from Gatan Inc., 780 Commonwealth Drive, Warrendale, PA. 15086, for the following laboratory equipment: a)Model 626-CRYOTRANSGFER SINGLE TILT HOLDER Summary: The above laboratory equipment is essential to NIAMS’s continued research efforts: Background: The laboratory equipment is essential and vital for the current clinical research of “Dynamics of Herpes Simplex Virus Capsid Maturation Visualized by Time-Lapsed Cryo-EM”, which is led and directed by these NIAMS researchers. J. Bernard Heymann, Naiqian Cheng, William W. Newcomb, Benes L.Trus, Jay C. Brown and Alasdair C. Steven The capsid of the herpes simplex virus initially assembles as a precursor procapsid that matures via a massive conformational change of its 192 MDa surface shell. This shell is composed of hexamers and pentamers of VP5 coordinated by heterotrimers of VP19c and VP23. The structural transition, which stabilizes the fragile procapsid, is facilitated by the viral protease which releases the interaction between the shell and the underlying scaffold: however, protease-deficient procapsids mature spontaneously albeit slowly in vitro. We have studied procapsid maturation as a time-resolved process by monitoring this reaction by cryo-electron microscopy. The resulting images were sorted into 17 distinct classes and three-dimensional density maps were calculated for each. Ordered into a time series, these data yielded “molecular movies” of procapsid maturation. A single major convulsion takes place at stages 8-9, preceded by relatively subtle adjustments in the pattern of interactions and followed by similarly small “aftershocks”. The primary mechanism underlying maturation is relative rotations of domains of VP5. The sole source determination is based upon the fact that the Cryotransfer holder must be 100% compatible with the government’s existing Gatan model 900.60ck SmartSet cooling control unit and 100% compatible with the government’s Gatan Temperature Control modules with seven-pin configuration. Gatan Inc. is the manufacturer of the aforementioned and therefore, the Model 626-CRYOTRANSFER SINGLE TILT HOLDER must be compatible to fit existing instruments and parts. Gatan is the only known system that meets the Government’s minimum needs. Delivery date: Fifteen days (15) after receipt of purchase order The offeror must include a completed copy of the following provisions: 1) FAR Clause 52.212-1 Instructions to Offerors Commercial; 2) FAR Clause 52.212-2, Evaluation Commercial Items. As stated in FAR Clause 52.212-2 (a), The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: Technical Evaluation and Price. 3) FAR Clause 52.212-3, Offeror Representations and Certifications Commercial Items; 4) FAR Clause 52.212-4, Contract Terms and Conditions Required To Implement Statues or Executive Orders Commercial Items, Contract Terms and Conditions Commercial Items; and 5) FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items Deviation for Simplified Acquisitions. This action is under the authority of 41 U.S.C. 253(c) (1), as set forth in FAR 6.302-1 and HHSAR 306-302-1. Only one responsible source and no other supplies or services will satisfy agency requirement. This notice of intent is not a request for competitive quotations however; all responses received within 15 days from the date of publication of this synopsis will be considered by the Government. Interested parties may identify their interest and capability to respond to the requirement or submit proposals. However, the determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. The offeror must include in their quotation, the unit price, the list price, shipping and handling cost. Note: In order to receive an award from the NHLBI contractors must have a valid registration in the Central Contractor Registration (CCR) www.ccr.gov and registered in Dun and Bradstreet (DUNS), the Taxpayer Identification and the certification of business size www.bpn.gov. The clauses are available in full text at http://www.arnet.gov/far. Quotations will be due fifteen (15) calendar days from the publication date of this synopsis or by August 12, 2008, 5pm, Eastern Standard Time. Responses will only be accepted if dated and signed by an authorized company representative. Interested vendors capable of furnishing the government with the item specified in this synopsis should submit their quotation to the below address. Inquires to this notice, referencing number NHLBI-PB-(AR)-2008-194-RCO, submitted in writing to the National Heart, Lung and Blood Institute, Office of Acquisition, Procurement Branch, 6701 Rockledge Drive, Suite 6128, Bethesda, Maryland 20892-7902. Attention: Ms. Rosie C. Owens, Contract Specialist. If submitted electronically: Email: Rosie C. Owens, Contract Specialist rowens@nhlbi.nih.gov or Ms. Kathleen Marsden, Contracting Officer marsdenk@nhlbi.nih.gov. Faxed copies will not be accepted.
- Web Link
-
FedBizOpps Complete View
(https://www.fbo.gov/?s=opportunity&mode=form&id=23635979c37bb93dde1c3b81b5dd8fb0&tab=core&_cview=1)
- Place of Performance
- Address: Bethesda, Maryland 20892-0001, Bethesda, Maryland, 20892-0001, United States
- Zip Code: 20892-0001
- Zip Code: 20892-0001
- Record
- SN01625171-W 20080731/080729223016-23635979c37bb93dde1c3b81b5dd8fb0 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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