SOLICITATION NOTICE
A -- Human Neurological Diseases Project
- Notice Date
- 10/30/2008
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- 779289
- Response Due
- 11/13/2008 3:00:00 PM
- Archive Date
- 11/28/2008
- Point of Contact
- Jasmine D Snoddy,, Phone: 301 594 1571
- E-Mail Address
-
snoddyj@mail.nih.gov
- Small Business Set-Aside
- N/A
- Description
- This is a notice of intent, not a request for a proposal. A solicitation document will not be issued and proposals will not be requested. The National Institute on Drug Abuse (NIDA), Station Support/Simplified Acquisition (SS/SA) Branch intends to solicit, negotiate and award a purchase order on a noncompetitive basis to The Research Foundation of State University of New York, Syracuse, New York, to complete a project that has implications for human neurological diseases. The first objective will be to determine the extent to which STK25 is influenced by Reelin-signaling in neurons. The second objective is to explore the role of STK25 in mouse brain development, in vivo. The project is to determine the role of STK25 in mouse brain development and disease. The period of performance is November 14, 2008-June 30, 2009. The Research Foundation of State University of New York maintains staff; Dr. Tohru Matsuki, who has been working to identify a modifier gene that regulates Tau phosphorylation in mutant mice. Tau phosphorylation is observed in a number of neurological conditions and correlate with cognitive decline. Dr. Matsuki identified the kinase STK25 as a molecule that upregulates Tau phosphorylation in a strain of mutant mice that had a severe neurological discover. Dr. Matsuki has also accumulated reagents that are available to other investigators. Dr. Matsuki’s experimental expertises include the manipulation of STK25 gene expression in mouse brain and tissue culture. Therefore based on the aforementioned facts, only one responsible source and no other supplies or services will satisfy agency requirement FAR 6.302-1. The Government intends to select the offer that represents the best value to the Government, price and all other factors considered. The acquisition is being conducted under simplified acquisition FAR 13 and is exempt from the requirements of FAR Part 6, Competition Requirement. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely with the discretion of the Government. Comments to this announcement, referencing synopsis number 779289 may be submitted to the NIDA, SS/SA Branch, 31 Center Drive, Room 1B59, Bethesda, MD 20892, Attention: Jasmine Snoddy.
- Web Link
-
FedBizOpps Complete View
(https://www.fbo.gov/?s=opportunity&mode=form&id=1fb8783c54553fc820c210f670f7007f&tab=core&_cview=1)
- Place of Performance
- Address: Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN01698544-W 20081101/081030215037-1fb8783c54553fc820c210f670f7007f (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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