SOLICITATION NOTICE
66 -- PerkinElmer Opera High Content Screening Reader
- Notice Date
- 12/10/2008
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-90012-MM
- Archive Date
- 1/3/2009
- Point of Contact
- Melissa P Marino, Phone: 301-402-4509, Caren N Rasmussen,, Phone: (301) 402-4509
- E-Mail Address
-
marinome@mail.nih.gov, cr214i@nih.gov
- Small Business Set-Aside
- N/A
- Description
- The National Cancer Institute (NCI), Center for Cancer Research (CCR), plans to procure a PerkinElmer Opera High Content Screening Reader. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(2) and 13.501-(a)(1) to use simplified procedures for commercial acquisitions. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. The CCR Confocal Core Facility in the Laboratory of Receptor Biology and Gene Expression (LRBGE) is available to all CCR investigators who require advanced light microscopy instrumentation and expert guidance in using it. The investigators now using this facility have a demonstrated need to perform high content, high-resolution imaging of living cells. These studies require the ability to automate imaging on thousands of samples while keeping them alive and then generating for each sample a high-resolution image in up to four different fluorescent channels. No such combined instrumentation capability is currently available within the LRBGE confocal core facility, or for that matter within the CCR. CCR requires confocal imaging capability with high numerical aperture objectives for the best resolution in four fluorescence channels. The system must also be capable of long-term live cell analysis. This means that imaging must be done in an environmental chamber with controlled temperature, humidity and CO2 levels, and that the system must provide for stable focus so that specimens do not drift out of focus during the experiment. The system must also be capable of delivering reagents to samples at prescribed times, so that measurements of cellular responses can be made. Finally, the system must be capable of automated, high-throughput imaging of up to 100,000 4 channel image sets in 24h. Facts and Reasons to Justify Other than Full and Open Competition 1.Statute Statute: 41 U.S.C. 253 (1) as set forth in FAR 13.106-(b)(2) and 13.501-(a)(1) (b) Solicitation from a single source. (2)For Sole source acquisition of commercial items in excess of the simplified acquisition threshold conducted pursuant to subpart 13.5, the requirements at 13.501(a) apply. No other requirement and/or type for supply or service will satisfy agency need. 2. Sole Source Justification: The following salient characteristics apply to the PerkinElmer Opera High Content Screening Reader: •Microscope system must utilize the confocal Yokogawa point scanning Nipkow spinning disc technology for optimal low light level, live-cell imaging •True Confocality in X,Y & Z, offering the best possible 3-D resolution •20x, 40x and 60x Automated Water Immersion Lenses for highest optical performance during unattended measurements •10x, 2.0, and 40x Air lenses for sample carriers with thick bottom or focus positioning deep into the sample •Variable automated magnifications including 10x, 20x, 40x, 60x to optimize z sectioning and resolution for the specific application •Primary dichroic filters of 488/561/640nm, 405/488/640nm, 405/488/561/640 on three separate light/camera paths. •Detection filters of 510/22arn, 568/22nm short, 438/22nin, 475,50nm, 650/40nm •Multiparameter simultaneous four (4) color detection •Instrument must be capable of combined simultaneous and sequential imaging •Point-Confocal excitation wavelengths including 405nm, 488nm, 561mn, 640nrn •Simultaneous non confocal UV excitation ranging barn 325nm to 410nm. •Three-(3) cooled CCD cameras and one-(1) additional CCD camera for non confocal detection using the UV option The PerkinElmer Opera High Content Screening Reader is the only known commercial instrument with these unique characteristics which are critical for research in the LRBGE confocal facility. This is not a solicitation for competitive quotations. However, if any interested party believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI contracting office on or before 11:00 AM EST on December 19, 2008. All questions must be in writing and can be faxed (301) 402-4513 or emailed to Melissa Marino, Contract Specialist at marinome@mail.nih.gov. A determination by the Government not to compete this proposed acquisition based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) www.ccr.gov and the Online Representations and Certifications Applications (ORCA), http://orca.bpn.gov. No collect calls will be accepted. Please reference solicitation No. NCI-90012-MM on all correspondence.
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