SOURCES SOUGHT
99 -- MRC NSHD Cohort Study
- Notice Date
- 1/7/2009
- Notice Type
- Sources Sought
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Aging, IRP, BRC, Pam Paradis, 410-558-8118National Institutes on Aging, IRPNIH Biomedical Research CenterSuite 100, Room 04C009251 Bayview BlvdBaltimoreMD21224-2815
- ZIP Code
- 21224-2815
- Solicitation Number
- NIHAG2009047
- Response Due
- 1/28/2009
- Archive Date
- 2/27/2009
- Point of Contact
- PARADIS, PAMELA +1 410 558 8118, paradisp@mail.nih.gov<br />
- Small Business Set-Aside
- N/A
- Description
- Then National Institute of Aging, IRP, intends to negotiate and award a purchase order on a noncompetitive basis with the Medical Research Council Group, 20 Park Cres, London, England W1B 1AL for a project entitled, Post-Doctoral Fellowship in Life Course Epidemiology. The Laboratory of Epidemiology, Demography and Biometry (LEDB), NIA has an agreement with the U. K. Medical Research Council (MRC) National Survey of Health and Development to provide post-doctoral fellowship training in life course epidemiology to LEDB fellows who will spend one year in London and then 1 year in Bethesda, MD. This joint training program was formalized in a Memorandum of Understanding (MOU) signed by Dr. Richard Hodes, NIA Director, and Dr. Dan Longo, NIA Scientific Director, in February, 2007. As part of this agreement LEDB, NIA will pay an accommodation fee to the MRC for the year that the fellow works in London. This fee will cover office space, computing facilities, computer, technical support and general support from the facility staff. The MRC NSHD, also known as the British 1946 Birth Cohort Study, is a prospective cohort study of a nationally representative sample of all British births that took place in the first week of March 1946. The NSHD is a socially stratified sample of 2815 males and 2547 females drawn from England, Scotland, and Wales which has been described extensively and remains representative in most respects of the British population. Since the initial assessment shortly after birth, the cohort has been reevaluated over 20 times. At the most recent follow-up in 1999, when study members were 53 years old, 3035 persons (56.6% of the original cohort sample 70.4% of those still alive and residing in England, Scotland, or Wales) were successfully contacted and provided information on their health and life circumstances. Of these, 1452 men and 1504 women (97.4% of those successfully contacted) were interviewed and underwent physical assessments in their homes by team of 82 trained research nurses. A wealth of information is available on the pre-school and school-age years of study participants. Pre-school data from 3 examinations prior to age 6 assess growth and development, illnesses, health care, diet and living situation. Extensive information from multiple contacts during school years includes these same kinds of data plus educational and behavioral assessments, including standardized testing and teachers, parents assessments. In 9 follow-ups from ages 19 to 53, data on health habits, risk factors for specific diseases, physiologic measures and disease outcomes were collected. Extensive information is available on parents and study participants socioeconomic status, including education and occupation. The study has been extremely productive, with over 300 publications in the areas of health, specific disease outcomes, education, behavioral problems, social and demographic studies, and birth cohort study methodology. Currently, active research projects are investigating cardiovascular health, diet musculoskeletal disease, cognitive function, womens health, mental health, and respiratory disease. The 1946 Birth Cohort Study data base is a superb resource that has not been duplicated anywhere in the world. We are just beginning to learn how the life course influences the aging process, the probability of living a long and a healthy life, and the onset of certain conditions and diseases of old age. There is a tremendous value in having lifetime data on persons entering old age, but prospectively collected data of this kind has not previously been available to researchers studying aging. The 1946 Cohort Study has the potential to provide major contributions to our knowledge of predictors of cognitive function, physical function, and disability, depression, bone health, arthritis, heart disease and pulmonary disease. The proposed NIA-MRC fellowship will offer a unique opportunity to utilize this data base and train with mentors who have extensive experience doing this type of research. Only one responsible source and no other supplies will satisfy agency requirements, 41 U.S.C. 253 (c) (1), FAR 6.302-1 (b) (1). The period of performance is 12 months. The North American Industry Classification (NAICS) is 541711 and the Standard Size is 6.5.
- Web Link
-
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(https://www.fbo.gov/?s=opportunity&mode=form&id=df1a98d6e789469d4f7702397722fd88&tab=core&_cview=1)
- Place of Performance
- Address: National institute on Aging251 Bayview Blvd.Suite 100, Rm., 04C009BaltimoreMD21224USA<br />
- Zip Code: 21224<br />
- Zip Code: 21224<br />
- Record
- SN01728546-W 20090109/090107220426-df1a98d6e789469d4f7702397722fd88 (fbodaily.com)
- Source
-
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