SOLICITATION NOTICE
A -- Microbiology and Infectious Diseases Biological Resource Repository (MID-BRR)
- Notice Date
- 4/9/2009
- Notice Type
- Presolicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Office of Acquisitions, 6700 B Rockledge Room 3214 MSC7612, Bethesda, Maryland, 20892-7612
- ZIP Code
- 20892-7612
- Solicitation Number
- RFP-NIAID-DMID-NIHAI2009053
- Archive Date
- 5/8/2009
- Point of Contact
- Nicole Gordon,, Phone: (301) 402-0972, Nichele Robinson,, Phone: (301) 402-2234
- E-Mail Address
-
gordonn@niaid.nih.gov, robinsonnc@niaid.nih.gov
- Small Business Set-Aside
- N/A
- Description
- Introduction The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. The NIAID, Division of Microbiology and Infectious Diseases has a requirement to establish a central repository that will provide one-stop shopping for research materials for the broad community of microbiology and infectious diseases researchers. The repository will receive, acquire, authenticate, produce, preserve, store and distribute most of the approximately 15,000 unique organisms and reagents needed to comprise the comprehensive collection. It will also distribute materials produced by other research service programs and Government-supported research projects. Description Research supported by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), strives to understand, treat, and ultimately prevent the myriad of infectious, immunologic, and allergic diseases that threaten millions of human lives. The NIAID Division of Microbiology and Infectious Diseases (DMID) supports extramural research to control and prevent diseases caused by all infectious agents other than HIV, including research to counter bioterrorism. This includes basic and applied research to develop and evaluate therapeutics, vaccines, and diagnostics that is funded through a variety of research grants and contracts. Toward this aim, DMID supports an array of research services. Included are programs that make preclinical and clinical translational research services, as well as organisms and state-of the art reagents, DNA sequencing, data and analytic tools, and biocontainment and core facilities, available to investigators (http://www3.niaid.nih.gov/research/resources/dmid/). For the most part, these services are currently provided through multiple, specialized programs. DMID seeks now, however, to adopt an integrated approach to the provision of services by creating unified, comprehensive, coordinated programs. This strategy is being employed to: advance science by promoting cross-fertilization across and within disciplines and approaches; serve the research community more conveniently; achieve efficient use of resources through economy of scale and avoidance of duplication; and provide the flexibility needed to respond to changing priorities. Accordingly, DMID is establishing the Microbiology and Infectious Diseases Biological Research Resources Program (hereinafter called the Biological Research Resources Program). The Biological Research Resources Program will integrate and consolidate the functions currently carried out by numerous NIAID-supported repositories (http://www3.niaid.nih.gov/research/resources/dmid/repos.htm). Of these currently supported programs, five concentrate on targeted groups of bacteria (Shiga toxin-producing Escherichia coli, resistant staphylococci, respiratory pathogens, and mycobacteria responsible for tuberculosis and leprosy); one is dedicated to emerging viruses and arboviruses; one focuses on Aspergillus species; and three are dedicated to individual parasites (filarial worms, schistosomes, and plasmodia). Another program focuses on NIAID Category A, B and C Priority Pathogens (http://www3.niaid.nih.gov/topics/BiodefenseRelated/Biodefense/research/CatA.htm). This program provides a comprehensive collection of research materials, including those deposited by other Government-supported research projects, to be made available to the biodefense and emerging infectious disease scientific communities. Together, these collections contain approximately 15,000 unique catalog items and more than a half million units for distribution. The Biological Research Resources Program is designed not only to meet the currently defined needs of scientific communities, but also to meet emerging needs for research materials as they are identified. The Biological Research Resources Program comprises multiple components. The Microbiology and Infectious Diseases Biological Resources Repository (MID-BRR) will serve as a central repository that will provide one-stop shopping for the broad community of microbiology and infectious diseases researchers. The MID-BRR will receive, acquire, authenticate, produce, preserve, store and distribute most of the organisms and reagents needed to comprise the comprehensive collection. A separate and complementary Request for Proposal (RFP) has been solicited for the Animal Models of Infectious Diseases program, which will provide the capacity to ensure a supply for the MID-BRR of organisms that must be grown in animals as well as reagents integral to research on these organisms. The Animal Models of Infectious Diseases program will work closely with the MID-BRR. The MID-BRR will also serve as a repository for research materials produced by other Government-supported research projects and research service programs. The MID-BRR Contractor is expected to interact with these programs as well. For the purposes of this contract, research materials include both organisms and reagents: •Organisms include, for example, bacteria, viruses, parasites, and fungi, including NIAID Category A, B and C Priority Pathogens (http://www3.niaid.nih.gov/topics/BiodefenseRelated/Biodefense/research/CatA.htm) and NIAID designated emerging infectious disease agents or organisms (http://www3.niaid.nih.gov/topics/emerging/list.htm). •Reagents include, for example, biochemical, biologic, cellular, genomic, immunologic and molecular specimens and/or resources integral to research on these organisms. Reagents may also refer to toxins and other agents such as prions; to antiviral and anti-infective drugs and therapeutics, chemicals, agents that modulate the immune system, vaccines, vaccine constructs and vaccine adjuvants, and diagnostic tools and kits for detection and measurement. It is anticipated that one cost reimbursement-type contract will be awarded on or about March 31, 2010, for a Base Period of one year plus Options to Extend the Term for up to six additional one-year periods (through March 30, 2017). In addition, the contract will include Options to Increase the Level-of-Effort in increments that may increase the total level-of-effort by a maximum of 28 FTEs per year. A total level of effort of 56 FTEs per year (116,480 total direct labor hours per year based on a Work Year of 2080 hours) for a period of performance of seven years (Base period plus six, one-year Options) is required. In addition, during any year of the contract, contractors must also be able to respond to requests to provide additional effort based on the exercise of Options in increments of 2 FTEs, 5 FTEs or 10 FTEs, up to a maximum of 28 FTEs per year. Contractors must provide, for example, the following labor mix: Professional Support: Project/Program Manager(s), Director(s) of Collections, Director(s) of Science Technicians and Support: Technical Manager(s), Collection Scientist(s), Regulatory Specialist(s), Compliance Director(s), Marketing Manager(s), Field Acquisition Specialist(s), Technical Writer(s), Biologist(s) Non-Professional Support: Operations Technician(s), Quality Systems Technician(s), Technical Service Representative(s), Customer Support staff(s), Clerical Any responsible offeror may submit a proposal that will be considered by the Agency. This RFP will be available electronically on/about April 23, 2009, and may be accessed through FedBizOpps http://www.fbo.gov/. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.
- Web Link
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- Record
- SN01789420-W 20090411/090409215916-b9f4d44d85f5f6e6092e5b8ef62797d7 (fbodaily.com)
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