SOLICITATION NOTICE
A -- Custom Genechip Microarrays
- Notice Date
- 7/20/2009
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- 1056781
- Point of Contact
- Vida - Niles, Phone: 301-827-2476
- E-Mail Address
-
vida.niles@fda.hhs.gov
(vida.niles@fda.hhs.gov)
- Small Business Set-Aside
- N/A
- Description
- REQ # 1056781 The Food and Drug Administration (FDA) is seeking Full and Open Competition for vendors that can provide quotes/proposals. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6, simplified acquisition procedures and the resultant of firm fixed price purchase order will include all applicable provisions and clauses in effect through the Federal Acquisition Circular 05-32. NAICS Code 541711 Project Title: Custom Salmonella/E.Coli Genechip Microarrays Background: The custom Genechip microarrays are to be utilized with an integrated Affymetrix GeneChip Scanner 3000 and Fluidics 450s system. This project will deliver high density microarrays to interrogate enteric pathogen groups and the pan-genome of the lower gastrointestinal tract commensal microbiota. This work will provide a useful tool with the capacity to monitor the metabolic and bacterial flux upon challenge, for instance, with pathogen outbreak strains. In addition, the arrays could have wide applicability towards vulnerable populations (immunocompromised), antibiotic resistance gene reservoirs and transmissibility, exposure to live microbial ingredients, and even the effects of food constituents and additives. These investigations are not necessarily limited to the human gut microflora, but rather can be expanded to other relevant hosts such as agricultural food producing animals that contribute to zoonotic transmission of foodborne pathogens. Furthermore, it supports the Center’s mission by investigating potential food risks with new and innovative approaches. Technical Requirements: The design and manufacturing of custom E. coli DNA microarrays must comply with the following requirements: The arrays must be able to be read/utilized by the Affymetrix GeneChip Scanner 3000 System. The GeneChip Scanner 3000 System is a fully integrated platform for conducting research using the Affymetrix GeneChip® Custom Genotyping assays and GeneChip probe arrays. The system includes the GeneChip Scanner 3000, Fluidics Station 450s, Hybridization Oven 640, a powerful computer workstation with dual Xeon processors loaded with GeneChip Operating Software (GCOS). The arrays must be high-density probe arrays capable of performing quantitative and simultaneous monitoring of thousands of genes. The arrays must be able to accomodate at least 85,000 unique genes and 1,000 control sequences (85,000 total probe sets). Furthermore, each of the gene sequence represented on this array must have 11 perfectly matched 25-mer probes as well as 11 mismatch 25-mer probes in order to estimate nonspecific hybridization. This results in an array capable of accomodating >2,500,000 individual features. Additionally, the size of each of these features must be 5 microns. The arrays must contain the following hybridization controls: bioB, bioC, bioD and cre. The arrays must contain a normalization control set of 100 probe sets. Delivery: The contractor shall deliver 60 days after receipt of order CCR: Vendor must be registered in the Central Contractor Register (CCR) prior to the award of the contract. You may register by going to www.ccr.gov. You will need to your Tax ID, Duns Number, Bradstreet number and banking information. QUESTIONS DEADLINE: All questions are to be submitted via email to Vida.Niles@fda.hhs.gov, no later July 24, 2009, 4:30 pm EST. QUOTATIONS DUE: All quotations are due to: Vida.Niles@fda.hhs.gov, no later than 4:30 pm, EST on August 04, 2009. PROVISIONS and CLAUSES: The provision at FAR 52.212-1, Instructions to Offerors Commercial Items applies to this solicitation. The following agenda has been attached to this provision: None. The clause at FAR 52.212-4, Contract Terms and Conditions, Commercial Items applies to this acquisition. The following agenda has been attached to the clause: None. The clause at FAR 52.212-5 Contract Terms and Conditions Required to Implement Statues or Executive Orders, Commercial Items applies to this acquisition. The following FAR clauses cited are applicable: FAR 52.217-8, FAR 52.222-26, FAR 52.222-35, FAR 52.222-36, FAR 52.232-33, FAR 52.246-9 and FAR 52.246-18. Clauses and provisions are incorporated by reference and apply to this acquisition. Responses to this notice shall be sent via email to Vida.Niles@fda.hhs.gov, Telephone calls will not be accepted. 1056781 Evaluation Factors The evaluation factors for this solicitation will be the ability to meet the technical requirements. Experience: The offeror’s experience in producing custom GeneChip probe arrays to perform quantitative and simultaneous monitoring. Relevant Experience The contractor shall describe their relevant experience in fulfilling this requirement. Identify other organizations with which you have acted as a contractor while participating in the same or similar efforts. Include the degree of your involvement, the size and complexity of the organization and other information describing your experience. Vendors shall submit the names of three laboratories that are currently using the instrument that can be contacted for experienced opinions on the use of their instruments. Past Performance Factor: Contractors shall submit a list of three (3) reference contracts. Contracts listed may include those entered into by the Federal Government, agencies of State and local governments and commercial customers. Contractors that are newly formed entities without prior contracts should list contracts and subcontracts as required above for all key personnel. The reference list of the three (3) references shall include the following information for each contract and subcontract: 1.Name of contracting activity 2.Contract number 3.Contract type 4.Total contract value 5.Contract work 6.Contracting officer and telephone 7.Program manager and telephone 8.Administrative contracting officer, if different from #6, and telephone Each vendor will be evaluated on performance under existing and prior contracts for similar products or services. Performance information will be used as an evaluation factor against which contractor’s relative rankings will be compared to assure best value to the government. The government will focus on information that demonstrates quality of performance relative to the size and complexity of the contract under consideration. Price: The offeror shall provide a price in accordance with the requirements of the technical specifications. Evaluation Criteria for Award: Award will be made to the party whose quote offers the best value to the Government, technical, past performance and price and other factors considered. The Government may award this contract to other than the lowest price technically acceptable quote. The Government will evaluate information based on the following evaluation criteria: 1) Technical 2) Past Performance and 3) Price. Technical and Past Performance combined is significantly more important than price. The FDA intends to make an award immediately after the response date of this notice. The award will be made in accordance with FAR Part 13, Simplified Acquisition Procedures.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/1056781/listing.html)
- Place of Performance
- Address: 8301 Muirkirk Road, Laurel, Maryland, 20708, United States
- Zip Code: 20708
- Zip Code: 20708
- Record
- SN01880844-W 20090722/090720235502-4044d1fd906256979093d6392925845e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |