SOLICITATION NOTICE
B -- Pharmacology and Physiology of the Substantia Nigra and Basal Ganglia Study
- Notice Date
- 11/18/2009
- Notice Type
- Presolicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- 1338812
- Archive Date
- 12/22/2009
- Point of Contact
- Jasmine D Snoddy, Phone: 301 594 1571
- E-Mail Address
-
snoddyj@mail.nih.gov
(snoddyj@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a notice of intent, not a request for a proposal. A solicitation document will not be issued and proposals will not be requested. The National Institute on Drug Abuse (NIDA) Station Support/Simplified Acquisition (SS/SA) Branch, on behalf of the National Institute of Neurological Disorder and Stroke (NINDS) intends to negotiate and award on sole source purchase order to Nikolay Novikov for the study Pharmacology and Physiology of the Substantia Nigra and Basal Ganglia. This study focus on determining how drugs which modify dopamine receptor stimulation affect dynamic patterns in neuronal spike trains and local field potentials in basal ganglia thalamocortical circuits in conjunction with changes in cortical function. To study neurophysiological changes associated with stroke and the effects of dopaminergic agents on these changes, we need to establish techniques to compare patterned and oscillatory activity of neurons within cortex and in the basal ganglia and interconnected brain areas such as the basal ganglia. This study will be integrated with imaging studies conducted by collaborators and will allow insight into the neurophysiological basis of changes observed with imaging techniques. Nikolay Novikov has experience with rat anesthesia and surgery, including vein and artery cannulation techniques and experience working with the electrode construction and recording techniques in the rat, and with monitoring rat behavior. Mr. Novikov has been trained with the software computer programs necessary for displaying the data from the recording studies in the context of the needs of our laboratory. He also has the experience with histological techniques and thus the skill to effectively process the rat brain tissue after the experiment for histological confirmation of the recording sites. The acquisition is being conducted under simplified acquisition using FAR 13 procedures and is exempt from the requirements of FAR Part 6, Competition Requirement. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely with the discretion of the Government. Comments to this announcement, referencing synopsis number 1338812 may be submitted to the NIDA, Station Support/Simplified Acquisition Branch, 31 Center Drive, Bldg. 31, Room 1B59, Bethesda, Maryland 20892-2080 and Attention: Jasmine Snoddy, Contract Specialist.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/1338812/listing.html)
- Place of Performance
- Address: Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02006838-W 20091120/091119000232-7207d60a0677a5be2a6fcd12f3c7617e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |