SOLICITATION NOTICE
A -- High Throughput Human & Rodent Cell Co-Culture Systems
- Notice Date
- 6/16/2010
- Notice Type
- Presolicitation
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- RTP Procurement Operations Division (D143-01) Research Triangle Park, NC 27711
- ZIP Code
- 27711
- Solicitation Number
- PR-NC-09-10693
- Response Due
- 9/15/2010
- Archive Date
- 10/15/2010
- Point of Contact
- JENNIFER B. HILL, Contract Specialist, Phone: 919-541-3083, E-Mail: hill.jennifer@epa.gov
- E-Mail Address
-
JENNIFER B. HILL
(hill.jennifer@epa.gov)
- Small Business Set-Aside
- N/A
- Description
- The US Environmental Protection Agency (EPA), Office of Research and Development, National Computation Center for Toxicology, Research Triangle Park, North Carolina has a requirement for the use of cell, organ or organism culture systems with complex and diverse biological capacities in order to measure chemical effects on critical pathways, processes and phenotypes relevant to human and ecological toxicity. Results from such screening studies would be used in the EPA?s ToxCast? and Virtual Tissues Programs. The EPA requires a Contractor to use validated, human, rodent, fish, amphibian or other systems with, for instance, the capacity for: metabolism of chemicals; differentiation of cells; cell to cell signaling; steroidogenesis; gene expression or epigenetic changes. Possible culture systems could include primary cells, stable cell lines, pluripotent cells, organotypic cultures, or simple but whole organisms useful for evaluating the effects of thousands of environmental compounds. The EPA requires a Contractor to use validated, complex culture systems with cells, tissues or organisms relevant to predictive toxicology and useful in evaluating the effects of a large library of compounds on those systems. In proposing assays, emphasis should be placed on the representation of complex biological capacities and responses of biological systems with the capability to be run in a reproducible, quantitative high throughput manner. The EPA will provide compounds at a minimum of 20 samples and a maximum of 3,000 samples per order. Each order of samples shall be processed and data submitted to EPA within 60 days of receipt of samples. The Government will order processing of a minimum of 100 samples for some combination of one or more CLIN, and a maximum of 10,000 samples for each CLIN during the anticipated contract. The applicable North American Industry Classification System (NAICS) code is 541712 with a small business size standard of 500 employees. EPA has determined that this action will be processed as a full and open competition. The award of Indefinite Delivery Indefinite Quantity (IDIQ) Task Order contract is anticipated with a 12 month base period and four option periods of 12 months each. Solicitation PR-NC-09- 10693, Request for Proposal (RFP), will be available on or around July 2, 2010. Proposals will be due approximately 45 days after the RFP issue date. No further synopsis will be issued. The solicitation and any subsequent amendments will only be available via the EPA RTP Procurement Website at http://www.epa.gov/oam/rtp_cmd. Hard copies or diskettes will not be available. Telephone and fax requests for a copy will not be honored. It will be your responsibility to frequently check the same website for any amendments or additional information that may become relevant, such as a pre-proposal conference. All responsible sources may submit a proposal which shall be considered by the Agency.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/EPA/OAM/CMD/PR-NC-09-10693/listing.html)
- Record
- SN02179720-W 20100618/100616235426-e2c8cb7e8d97ef1a95b2a67b831e7082 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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