SOLICITATION NOTICE
66 -- Laboratory Equipment
- Notice Date
- 9/13/2010
- Notice Type
- Justification and Approval (J&A)
- NAICS
- 423450
— Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-PB-HG-2010270-RSF
- Archive Date
- 9/14/2010
- Point of Contact
- Rashida S. Ferebee, Phone: 3014352605
- E-Mail Address
-
ferebeers@nhlbi.nih.gov
(ferebeers@nhlbi.nih.gov)
- Small Business Set-Aside
- N/A
- Award Number
- HHSN268201000355P
- Award Date
- 8/4/2010
- Description
- 1. Program Office: NHGRI 2. Project Officer: 3. Project Information: Tecan Infinite M1000 Title: Period of Performance: 30 Days After Award Requisition No. Proposed Contractor: Tecan U.S. Inc. 4. Description of what is to be acquired and the Benefit received by the Government: The subject requisition is for the procurement of the Tecan Infinite M1000. This is a microplate reader-spectrometer that includes monochromator optics capable of collecting uv-vis and 3D fluorescence spectra as well as single-wavelength studies of microplate contents. The National Institutes of Health Chemical Genomics Center has begun transitioning into the broader scope National Center for Translational Therapeutics. This request is required for this Laboratory in order to develop and deploy new technology and assays for the screening of rare and neglected disease targets. This item is needed to facilitate our assay development and technology evaluation program. The Tecan Infinite M1000 will be used for a wide variety of applications for which it is suited, ranging from ratiometric, multiplexed reporter assays, to the characterization of chemical and natural product extract libraries at various stages of purification. It will also be used to determine possible interference in any qHTS assay that library is run against, and counterscreens to verify such interactions. The Tecan M1000 is needed to facilitate NCGC’s assay development and technology evaluation program. This program is to provide extramural and intramural researchers with access to assay development support, as well as allow the Laboratory to evaluate novel assay formats. NCGC will work as a collaborative resource for doing assay development and validation screening. The Tecan Infinite M1000 will be used for a wide variety of applications for which it is suited, ranging from ratiometric, multiplexed reporter assays, to the characterization of chemical and natural product extract libraries at various stages of purification. It will also be used to determine possible interference in any qHTS assay that library is run against, and counterscreens to verify such interactions. 5. Independent Government Estimate: N/A 6. Specific, detailed explanation of why it is not feasible to obtain full and open competition. Sole Source Justification. The Tecan Safire Microplate Spectrometer Reader, a predecessor to the Infinite M1000, has been and is in current use extensively at NCGC for compound library characterization, as well as assays. These established protocols would need to be adapted and re-assessed if moved to another platform, as well as requiring the in-house expertise that already exists to require training on a different platform. Additionally, the extensive data collected and analyzed using methods developed with Magellan data analysis software and formats would need to be built from the ground-up for a different system, and possibly recollected on a different platform. As an example, in-house software we spent considerable time to develop and optimize to find the extinction coefficients of uv-vis absorbance maxima from 1536-well compound library plates collected on the Tecan platform would need to be re-written, if possible, to accommodate a different data format. The Infinite M1000 is unique because it can access a variety of microplate experiments within a single instrument. It can perform multiwavelength experiments, such as assays using dual fluorescent labels or two-color luminescent reporters, as well as collect full 2D UV, visible, near-IR, and 2D and 3D fluorescence spectra. The Tecan Infinite M1000 uses a monochromator-based detection system that eliminates the need for a collection of optical filters that need to be changed when changing assay detection wavelengths, so for example, assay plates with different dual-fluorescent label systems, can be studied back-to-back without the need to aquire different filter sets. 7. Statutory Authority. Federal Acquisition Regulation (FAR) Subpart 13.106-1. (b) Soliciting from a single source. (1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, or industrial mobilization). No other requirement and/or type for supply or service will satisfy agency need. 8. Market research: SBA search, no other businesses could provide the equipment that would fulfill the Government’s needs.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-PB-HG-2010270-RSF/listing.html)
- Place of Performance
- Address: NHGRI, ROCKVILLE, Maryland, 20850, United States
- Zip Code: 20850
- Zip Code: 20850
- Record
- SN02279647-W 20100915/100913235843-3cab2d75b17b7de1143b016acfd5e038 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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