SOURCES SOUGHT
66 -- Motorized Inverted Research Microscope
- Notice Date
- 6/23/2011
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- 1089484
- Archive Date
- 7/12/2011
- Point of Contact
- Howard Nesmith, Phone: 870-543-7459
- E-Mail Address
-
howard.nesmith@fda.hhs.gov
(howard.nesmith@fda.hhs.gov)
- Small Business Set-Aside
- N/A
- Description
- MARKET RESEARCH PURPOSES ONLY NOT A REQUEST FOR PROPOSAL OR SOLICITATION Small And Any Other Size Business Are Encouraged To Respond The U.S. Food and Drug Administration (FDA), Jefferson Laboratories, in Jefferson, Arkansas, is conducting market research to support the Lab of DNA Viruses, within the Division of Viral Products located at the Center for Biologics Evaluation and Research (CDER). The Laboratory of DNA viruses has need for an inverted fluorescence microscope to visualize cells infected or not with DNA viruses. This microscope must be easy to use, reliable, efficient, and provide applications versatility and best image quality. The system must be able to be fully or partially computer controlled, integrated with multiple objective lens, multi-fluorescence filters, and super sensitive camera. The inverted fluorescence microscope platform must be upgradeable for more automotive controls. Only new equipment will be considered. Used or refurbished equipment will not acceptable. Item #1 Quantity of One (1) Motorized Inverted Research Microscope Technical Requirements • Shall be capable of High-quality Phase Contrast Observation • Shall have Built-in Perfect Focus System (PFS) for automatic focus correction • Shall have a photo activation unit allows cell marking and dynamic analysis using photoactivatable and photoswitchable proteins such as PA-GFP and Kaede. • Shall have diverse image acquisition and analysis methods such as multi-dimensional time-lapse imaging to acquire temporal, spatial and spectral information of fast, dynamic live cell processes. • Shall have applications such as confocal, FRET, and High Content Analysis (HCS),and photobleaching/photo activation to study interaction of fluorescence protein molecules in living cells and tissues • Shall have correction of focus drift during long-term observation and when reagents are added. • Shall employ 870nm wavelength for the coverglass interface detection so that near-infrared fluorescence dyes including Cy5.5 can be used. • Shall have multiple image port design for left, right or bottom ports for optical output to position the camera in any position. • Shall incorporate a phase ring-that was normally positioned within the phase contrast objective lens-into the external phase contrast unit optically so it allows use of specified high NA objectives to produce high-resolution phase contrast images. • Shall include the 60x and 100x TIRF objectives with the highest numerical aperture of 1.49 • Shall have a water immersion objective for phase contrast observation. • Shall have ability to use laser tweezers without changing the objective lens • Shall have motorized laser TIRF for observation of cell membrane dynamics and single molecule capture of high-resolution images in the entire frame for each wavelength • Shall be capable of time-lapse imaging. • Shall have operation buttons on both sides of microscope body. • Shall have aVFD screen and operation buttons on front of microscope body • Shall have a high-definition 5.0-megapixel cooled color camera head that features high frame rate, high red sensitivity, high resolution and accurate color reproduction. Firms believing they offer an equivalent Motorized Inverted Research Microscope to the above specifications are encouraged to respond electronically via email to the attention of Howard Nesmith at howard.nesmith@fda.hhs.gov on or before June 27, 2011 by 9:00 AM (Central Time) with no less than the following information: • Business name, DUNS number, business address, business website, business size status (i.e., SB, VOSB, SDVOSB, HUBZone SB, SDB, WOSB, LB), point of contact name, mailing address (if different from business address), phone number and email address; [North American Industry Classification System (NAICS) Code is 334516 - Analytical Laboratory Instrument Manufacturing. Small Business Size Standard is 500 employees. • Sufficient descriptive literature that unequivocally demonstrates that offered products meet or exceed above specifications. • Though this is not a request for quote, informational pricing may be submitted. The government is not responsible for locating or securing any information, not identified in the response. For information regarding this market research effort, please contact Howard Nesmith at howard.nesmith@fda.hhs.gov. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). Notice of Intent In the event no responses (included no acceptable response) received to this market research effort this will serve as the notice effort to enter into a sole source contract with Nikon Instruments, Inc., for their Ti-E Motorized Inverted Research Microscope including the following items: Nikon Ti-E Motorized Inverted Research Microscope: *********************************************** Ti-E Inverted Microscope Ti-HUBC/A Hub Controller A Ti-AC/A AC Adapter for HUBC/A Ti-AC120 Power Cord 120V Ti-SSR Rect Mech Stage Short Handle Ti-OH Oia Pillar Illuminator 100W O-LH/LC Precentered Lamphouse with LC Halogen Lamp 12V 100W L.L Filter 45mm NCB11 Filter 45mm NO 16 A Ti-PS100W Power Supply 10D-240V Ti-100WRC 100W Lamphouse Remote Cable Power Cord Ti-T-B Eyepiece Base Unit Ti-TS Eyepiece Tube S CFI10X Eyepiece F.N. 22mm Eclipse Large Nylon Cover 14x26x32 Condenser System *********************** Ti-C System Condenser Turret Ti-C-LWD LWD Lens Unit for System Condenser Turret TE-C LWD Ph1 Module TE-C LWD Ph2 Module TE-C LWD Ph3 Module Nosepiece and Objectives: ******************************* Ti-N6 Sextuple Nosepiece CFI Plan Fluor DL 10X NA 0.3 WD 16.0 mm CFI Super Plan Fluor ELWD 20XC ADM NA 0.45 WD 8.2-6.9mm (Ph1) CFI Super Plan Fluor ELWD 40XC ADM NA 0.60 WD 3.6-2.8mm (Ph2) CFI Plan Fluor DLL 100X OIL NA 1.3 WD 0.16 8CC Immersion Oil Each Widefield Fluorescence System ************************************* TI-FL Epi-FL Attachment Wide Field Fluorescence Illuminator Ti-FLC-E Motorized Epi-FI Filter Turret for Ti-Series C-FL DAPI HC HISN Zero Shift C-FL GFP HC HISN Zero Shift C-FL Texas Red HC HISN Zero Shift C-FL Cy5 HC HighlSn Zero Shift C-HGFIB HG 100W Adapter R for all Biological 100 Watt Microscope Systems C-HGFI Intensilight Hg Illuminator C-LHGF I HG Lamp (required for both versions) C-HGF IF 30 HG Fiber (3000mm Fiber Optic Light Guide) Power Cord Digital Imaging System *************************** Q-Imaging QIClick, Mono, 12-bit, non-cooled; includes 1394 Firewire, PCI card, Neutral Density Filter. C-MountliSO Adapter, 1X 64bit PC Workstation supplied with Intel Core i5 2.66 GHz processor -8GB DDR3 RAM -Gigabit LAN adapter, USB keyboard and laser mouse -1GB display adapter (supports two monitors) -16x BluRaylDVD/CD writer -8OGB Solid State OS drive and 1 TB SATA data drive -Includes 7 outlet surge protector, USB-to-RS232 adapter, DisplayPort to DVI-D Adapter -Installed with Windows 7 64bit Professional Edition & includes recovery disk -Includes 3 years parts, labor, and onsite service standard warranty 21.5 inch wide-format TFT active matrix LCD monitor -with height, swivel, and tilt adjustment. -Connects to PC by Display Port, DVI-D, VGA connectors -1000:1 contrast ratio with 1780 viewing angle -supporting up to 1920x1080 @ 60Hz -Includes 3 years parts, labor, and on-site service standard warranty. NIS-Elements: Basic Research (Multi License): Acquisition and analysis package, includes camera and Nikon motorized microscope drivers NI8-Elements: Module: 4D imaging - acquisition module for up to 4 dimensions, including any two of the following: time, channel or wavelength and focus
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/1089484/listing.html)
- Place of Performance
- Address: U.S. Food & Drug Administration, 8800 Rockville Pike, Rockville, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02480463-W 20110625/110623234919-02a2f178b2b83a67c1eca7aca3cb246e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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