SOLICITATION NOTICE
R -- Pilot for Assessment of Accelerometers in the Elderly with Cardiac Conditions
- Notice Date
- 7/25/2011
- Notice Type
- Presolicitation
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- 2169646
- Point of Contact
- Susan Nsangou, Phone: 3014432104
- E-Mail Address
-
nsangous@mail.nih.gov
(nsangous@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested. National Institute on Drug Abuse, Office of Acquisitions- Neurosciences, Station Support/Simplified Acquisitions on behalf of the National Institute on Aging (NIA) intends to negotiate on a sole source basis with the Trustees of Columbia University in the City of New York, Health Sciences Division, Columbia University Medical Center, 630 W 168th Street, New York, NY for the services of collection of data from clinical participants using accelerometers. Objective measurement of physical activity is developing quickly with innovations in the design of accelerometers. The accelerometers have increased capabilities for collection of information on the intensity, duration, patterns, and even type of movement. This generation of accelerometers now include increased capacity for signal storage, collection of raw unfiltered signals in dense time, amplitude, and frequency resolutions, collection of triaxial rather than uniaxial data, and the configurations of accelerometers for wear in a variety of positions on the body, including wrist, thigh, and hip. The quality of information that can be captured from these accelerometers creates the opportunity for many more potential applications that were more difficult when less data were available. This PSC will allow pilot testing of a new application of accelerometry to assess function in free-living populations and how this changes over time in response to a surgical intervention. There are few objective tools available to assess function in free-living populations. There is a need for these instruments, especially in clinical trials where populations may be too frail to undergo rigorous functional testing or may not return to clinic for follow-up. This pilot test will assess the utility of accelerometry to capture clinically relevant change in patterns of daily activity by collecting pre-operative daily data on persons undergoing evaluation for transcatheter aortic valve implantation (TAVI) and post-operative daily recovery data on persons who undergo TAVI or aortic valve replacement (AVR). Surgery for aortic stenosis is often performed late in life but has been shown to be clinically warranted even in quite older, selected patients. Unfortunately, many patients with severe aortic stenosis are too ill to undergo open heart surgery. In Europe, a new method for replacement of aortic valves has been used for several years involving replacement through arterial access without the burden of open-heart surgery. This modality for valve replacement is being evaluated for FDA approval in the US. Columbia University has a Clinical Cardiovascular Research Laboratory for the Elderly. The investigators have already conducted a study of long-term monitoring for congestive heart failure so they have some experience in long-term monitoring and how to manage this with substitution of devices. In addition, their program is part of the leadership of the studies of TAVI versus AVR and they therefore have a large through-put of patients which makes it possible to conduct such a pilot study. The investigators are interested in identifying additional ways to characterize the recovery after an intervention for aortic stenosis. The NIA interested in these patients because this is one of the few surgical interventions we could identify where patients are expected to improve post-operatively. This is an opportunity to see whether these improvements can be identified on accelerometry and potentially to establish the utility of objective measures with accelerometry. Lastly, Dr. Green and his colleagues at Columbia have already implemented a protocol to collect much of the ancillary data that will be needed in order to assess the accelerometry data. This center is a unique resource and justifies a sole source contract. The acquisition is being conducted under simplified acquisition using FAR 12 procedures and is exempt from the requirements of FAR Part 6, Competition Requirement. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely with the discretion of the Government. Comments to this announcement, referencing synopsis number NOI2169646 may be submitted to the NIDA, Station Support/Simplified Acquisition Branch, 31 Center Drive, Bldg 31, Room 1B59, Bethesda, MD 20892-2080, and Attention: Susan A. Nsangou, Contracting Officer.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/2169646/listing.html)
- Place of Performance
- Address: New York, New York, United States
- Record
- SN02509890-W 20110727/110725235323-9083ba56ffff219c3257828b15fbb3e2 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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