SOLICITATION NOTICE
68 -- Purchase custom chemical hydrolysis of 6 PAH epoxide metabolites
- Notice Date
- 8/16/2011
- Notice Type
- Presolicitation
- NAICS
- 325199
— All Other Basic Organic Chemical Manufacturing
- Contracting Office
- Department of Health and Human Services, Centers for Disease Control and Prevention, Procurement and Grants Office (Atlanta), 2920 Brandywine Road, Room 3000, Atlanta, Georgia, 30341-4146
- ZIP Code
- 30341-4146
- Solicitation Number
- 99868
- Archive Date
- 9/15/2011
- Point of Contact
- Vallerie M Redd, Phone: 770-488-2845
- E-Mail Address
-
gfj3@cdc.gov
(gfj3@cdc.gov)
- Small Business Set-Aside
- N/A
- Description
- The Centers for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH), intends to award a sole source contract to Sigma-Aldrich, 2931 Soldier Springs Road, Laramie, WY 82070 for the acquisition of custom chemical hydrolysis of 6 PAH epoxide metabolites and isolation and purification of the tetrol products. The 6 epoxides are: Benz(a)anthracene-trans-8,9-dihydrodiol-10,11-epoxide (anti) Benz(a)anthracene-trans-8,9-dihydrodiol-10,11-epoxide (syn) Benz(a)anthracene-trans-3,4-dihydrodiol-1,2-epoxide (syn) Chrysene-trans-1,2-dihydrodiol-3,4-epoxide (anti) Chrysene-trans-1,2-dihydrodiol-3,4-epoxide (syn) 1,2-dihydroxy-3,4-epoxy-1,2,3,4-tetrahydrophenanthrene The statutory authority for this sole source acquisition is 10 U.S.C 2304(c)(1) in accordance with FAR Part 6.302-1- only one responsible source and no other supplies or services will satisfy the agency requirement. The NAICS code for this procurement is 325199, All Other Basic Organic Chemical Manufacturing. The period of performance for this procurement is 4 months. Sigma-Aldrich RTC is the only company that can provide the custom hydrolysis reactions of these 6 PAH epoxides and subsequent isolation and purification of the tetrol products to meet all of the program requirements including purity, cost and time constraints. Tobacco smoke contains a large number of toxic chemicals, including large PAHs with 4 or more aromatic rings. These PAHs can be metabolized into tetrol metabolites and excreted in urine. Measurement of these PAH tetrol metabolites could aid researchers to study human exposure to these large PAHs in tobacco smoke and study potential health effects from tobacco smoke. In order to develop methods to measure these metabolites, we need analytical standards for identification and accurate measurement. We have previously purchased 6 PAH epoxides as listed above. These expoxides can be hydrolyzed to yield PAH tetrols. Sigma-Aldrich RTC is the only company that can conduct chemical hydrolysis of these expoxides and purification of the tetrol products in the timeframe that is needed for the FDA tobacco project. There is no other company that can provide the custom hydrolysis reactions of these 6 PAH epoxides and subsequent isolation and purification of the tetrol products within the required timeframe. The PAH tetrol products will be used in a tobacco project that has specific deliverable requirements within certain times. As a result of this synopsis, no competitive solicitation will be posted on FedBizOpps. We will issue only one solicitation to Sigma-Aldrich. However, all responsible sources that believe they can meet these requirements may submit their capabilities/qualifications statement to provide the services to Vallerie Redd VIA E-MAIL ONLY at gfj3@cdc.gov with the solicitation number 99868 referenced in the subject line NO LATER THAN August 31, 2011. A determination by the Government not to compete this proposed action will be based on responses to this notice and are solely within the discretion of the Contracting Officer. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/CDCP/PGOA/99868/listing.html)
- Record
- SN02536585-W 20110818/110817000047-ba173fc73cfdbfae28a28c7731b345c7 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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