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FBO DAILY ISSUE OF APRIL 19, 2012 FBO #3799
SOLICITATION NOTICE

A -- Coordinating Center (CC) - Jackson Heart Study (JHS) Renewal

Notice Date
4/17/2012
 
Notice Type
Presolicitation
 
NAICS
541712 — Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 
ZIP Code
20892-7902
 
Solicitation Number
NHLBI-HV-13-09
 
Point of Contact
Austin Sachs, Phone: 301-435-5245
 
E-Mail Address
sachsa@nhlbi.nih.gov
(sachsa@nhlbi.nih.gov)
 
Small Business Set-Aside
N/A
 
Description
The National Heart, Lung, and Blood Institute (NHLBI) anticipates that Request for Proposal (RFP) NHLBI-HV-13-09 will be available on or about May 2, 2012. The Division of Cardiovascular Sciences of the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), plans to establish one (1) Coordinating Center as part of the Jackson Heart Study (JHS) renewal. The JHS also involves a Field Center, Training and Education Center and a Community Outreach Center. Awards for the JHS are anticipated to be made on or about June 1, 2013. The JHS is a multi-center investigation of predictors of cardiovascular disease (CVD) in 5,301 African-Americans living in Hinds, Madison, and Rankin Counties surrounding the Jackson, MS metropolitan area. The JHS represents an expansion of the Jackson, Mississippi site of the Atherosclerosis Risk in Communities (ARIC) Study to increase data collection in an African American population, and improve access to and the participation of African American populations and scientists in biomedical research and professions. The JHS was initiated in 1998 as a collaborative effort among three Jackson-area academic institutions. At the close of the current contracts in May 2013, the JHS will have completed three back-to-back cohort examinations that have produced extensive longitudinal data on traditional and putative CVD risk factors, socioeconomic and sociocultural factors and biochemical analytes; measures of subclinical disease from echocardiography, cardiac magnetic resonance imaging (MRI), computed tomography (CT) scans of the heart, aorta and abdomen; and stored biological samples. Eighty-two percent of the surviving JHS participants (N = 4,203) completed Exam 2; projected retention for Exam 3 is 80% (N = 4,082). In addition, the JHS has conducted annual cohort follow-up contacts for incident clinical events of interest, a variety of community education and outreach activities to promote healthy lifestyles to reduce disease risk burden, and level-appropriate academic training programs to promote and support public health research. The objectives of the renewal of the JHS program are to: 1) Support dedicated time for JHS investigators to conduct data analysis and prepare manuscripts using the wealth of data collected. 2) Facilitate access to study resources and expertise in order to: • Engage researchers beyond the JHS, including early career investigators, in collaborative analysis of existing data to produce high quality publications. • Serve as a training ground for undergraduate and graduate students to help ameliorate the shortage of minority biomedical researchers. • Serve as a platform for ancillary studies. 3) Conduct annual phone interviews with participants to identify interim hospitalizations and outpatient medical visits, convey information about the JHS, and serve as a vehicle to recruit for ancillary studies. 4) Continue clinical events identification, investigation, and validation to improve statistical power for risk prediction and hypothesis testing. 5) Perform community health education activities to disseminate health promotion and prevention messages in the Jackson community. 6) Prepare all remaining cleaned data, in SAS format (1999-2018), along with necessary documentation for their use and provide all biological specimens collected and maintained. NHLBI plans to support one (1) Coordinating Center, one (1) Field Center, up to two (2) Training and Education Centers, and one (1) Community Outreach Center. THIS NOTICE ADDRESSES THE COORDINATING CENTER ONLY. The Coordinating Center shall be responsible for overall study coordination, communications, data management, data analysis and manuscript production, analytical/statistical support, and publication of important JHS findings in peer-reviewed journals. The Contractor will maintain via subcontracts or other arrangements a Central Laboratory to manage the JHS stored biological samples; an Image Repository to manage JHS cardiac CT and MRI scans and echocardiograms; a formal collaboration with the ARIC study Coordinating Center for clinical events validation; and other subcontracts as required for study operations. This is a presolicitation notice only, not a request for proposal (RFP), and the Government is not committed to award a contract pursuant to this announcement. The solicitation, solicitation amendments, and all questions and answers related to this procurement will be made available via the Internet at https://www.fbo.gov/. The solicitation is anticipated for release to the vendor community on or about May 2, 2012 and will only be available via the Internet at the above web site. Potential offerors are responsible for accessing the web site and downloading the RFP and all attachments. It is also the offerors’ responsibility to monitor the FedBizOpps web page for the release of the solicitation and any amendments to the RFP. Interested parties must respond to the solicitation in order to be considered for award of any resultant contract. Letters of intent are due no later than June 8, 2012. This acquisition has been designated as a full and open competition under the North American Industry Classification System (NAICS) code 541712. Subcontracting opportunities are anticipated during the course of this contract award. Potential offerors are required to direct all questions via e-mail to sachsa@nhlbi.nih.gov. NOTE: PREPARATION COSTS – This presolicitation notice and the subsequent solicitation notice does not commit the Government to pay for preparation and submission of any materials.
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-HV-13-09/listing.html)
 
Record
SN02723881-W 20120419/120417235056-9c20c3112de52976e2366aa33b20a97e (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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