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FBO DAILY ISSUE OF APRIL 29, 2012 FBO #3809
SOLICITATION NOTICE

66 -- DNA Methylation Arrays and Processing Accessories

Notice Date

4/27/2012
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
 

ZIP Code

20857-0001
 

Solicitation Number

1103069
 

Archive Date

5/16/2012
 

Point of Contact

Howard Nesmith, Phone: 870-543-7459
 

E-Mail Address

howard.nesmith@fda.hhs.gov
(howard.nesmith@fda.hhs.gov)
 

Small Business Set-Aside

N/A
 

Description

This is a combined synopsis/solicitation for commercial items prepared in accordance with the Federal Acquisition Regulation (FAR) format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The government intends to issue a Purchase Order in accordance with FAR PART 13.106 for the below requirement under Simplified Acquisition Procedures. The solicitation number is 1103069. This solicitation is issued as a Request for Quote (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-58, April 18, 2012. The associated North American Industry Classification System (NAICS) Code is- 334516 - Analytical Laboratory Instrument Manufacturing; Small Business Size Standards is 500 in number of employees. Respondents are responsible for delivery in person, by e-mail, fax, mail or other delivery method their complete proposal and any additional documents before 9:00 am (Central Standard Time - Local Prevailing Time in Jefferson, Arkansas) on May 1, 2012 to james.rawls@fda.hhs.gov, Fax (870) 543-7990, or mail to the U. S. Food and Drug Administration (FDA), OO/OFBA/OAGS, Attention of Howard Nesmith, 3900 NCTR Road, Jefferson, AR 72079-9502. PLEASE NOTE - The above contact information is for the Contracting Office and not necessarily the delivery address. The delivery address is indicated in the FOB Destination section below. When appropriate, Respondents should consult with delivery providers to determine whether their documents will be delivered prior to the scheduled time. For information regarding this solicitation, please contact Howard Nesmith by e-Mail at howard.nesmith@fda.hhs.gov. The Food and Drug Administration is soliciting for DNA Methylation Arrays and Processing Accessories quotes for NCTR's Roche NimbleGen DNA Microarray Hybridization System. Item #1 Processing Accessories Consisting of: 1 ea - Array Processing Accessories Kit (05223539001) Components: 1 - Slide Rack 4 - Wash Tanks 8 - Slide Containers 10 - X1 Mixer (05223725001) 100 - DNA Methylation 385K Arrays / 6019043465 (05224373001) 1 - Hybridization Kit (05583683001) Components: 1 - 1200µl Vial 2X Hybridization Buffer 1 - 500µl Vial Hybridization Component A 1 - 60µl Vial Alignment Oligo 1 - Wash Buffer Kit (05584507001) Components: 1 - 2 x 540ml Vial10X Wash Buffer I 1 - 540ml Vial10X Wash Buffer II 1 - 540ml Vial10X Wash Buffer III 1 - 2 x 185mg Vial DTT 1 - 3 x 1000µl Vial Nuclease-Free Water 3 - Dual-Color DNA Labeling Kit (06370250001) Components: 1 - 2 x 1.85ml Vial PCR Grade Water Clear Cap Color 1 - 2 x 1.1ml Vial Random Primer Buffer Blue Cap Color 1 - 1 x 25 O.D. Vial Cy3-Random Nonamers Green Cap Color 1 - 1 x 25 O.D Vial Cy5-Random Nonamers Red Cap Color 1 - 2 x 50 μl Vial Klenow Fragment (3'->5' exo-) 50U/µl Yellow Cap Color 1 - 2 x 250 μl Vial dNTP Mix (10mM each dNTP) Purple Cap Color 1 - 2 x 550 μl Vial Stop Solution Brown Cap Color The Arrays shall meet the following needs:  The DNA methylation arrays shall contain at least 385,000 unique probes in order to provide comprehensive coverage throughout the rat genome  These DNA methylation microarrays shall have high sensitivity and specificity in order to readily detect as low as two methylated CpGs in a 500 bp fragment  The DNA methylation array reagents shall allow low sample input of 10 ng or less genomic DNA per labeling reaction without amplification bias  The microarray reagents shall utilize a Cyanine dye-based direct labeling method for labeling and hybridization for optimal microarray performance  The slides shall fit a 1 "x3" glass slide format for fluorescent image scanning with barcode labels Items shall be the same as or equal to the Roche Part Numbers provided in prentices ( ) for each of the above items. Items (Inclusive) Price: _____________________ GSA Contract Number (if applicable): ________________________ FOB Destination - U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), 3900 NCTR Road, Jefferson, AR 72079. Contract Type - Commercial Item - Firm fixed price. Simplified procurement procedures will be utilized. The provision at FAR 52.212-1 Instructions to Offerors - Commercial Items applies to this solicitation. Addendum to FAR Clause 52.212-1: FAR 52.212-1(c) is amended to require the offer to hold their offer firm through 30 Sept. 2012. The provision at FAR 52.212-2 Evaluation-Commercial Items is applicable to this solicitation. The specific evaluation criteria to be included in paragraph (1) of that provision are as follows: The Government will award the purchase order to the responsible offeror who offer conforming to the solicitation will be the most advantageous to the Government on price and other factors considered. The following factors shall be used to evaluate offers: (i) Technical capability of the services offered to meet the Government's requirement. (ii) Price. The government will award the purchase order to the lowest price technically acceptable quote. Technical capability will be determined by review of information submitted by the quoter, which must provide a description in sufficient detail to show that the item quoted meet the Government's requirements and will function with the equipment identified. The government is not responsible for locating or securing any information, which is not identified in the proposal. To ensure information is available, vendors must furnish as part of their proposal all descriptive material necessary for the government to determine whether the service meets the technical requirements. Quotes shall include technical specifications, descriptive material, literature, brochures and other information corresponding to each minimum required item, which demonstrates the capabilities of the offeror. The Provision at FAR 52.212-3, Offerors Representations and Certifications-Commercial Items, applies to this acquisition. An offeror shall complete only paragraph (b) of the provision if the offeror has completed the annual representations and certification electronically at http://orca.bpn.gov. The clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (Mar 2012), applies to this acquisition. The following additional FAR clauses cited in this clause are applicable: 52.204-10, 52.209-6, 52.222-3, 52.222-19, 52.222-21, 52.222-26, 52.222-36, 52.225-3 Alt II, 52.225-13,52.223-18, and 52.232-33. Clauses and provisions incorporated by reference can be obtained at https://www.acquisition.gov/far.
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/1103069/listing.html)
 

Place of Performance

Address: U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), 3900 NCTR Road, Jefferson, Arkansas, 72079, United States

Zip Code: 72079
 

Record

SN02733428-W 20120429/120427235424-de148132b3c110d6cc460731b7914925 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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