SOLICITATION NOTICE
B -- Evaluation of Host-Targeted Bait Box, Select Tick Control System to Reduce Entomological Risk of Lyme Disease in a Lyme-Endemic Area of North Central New Jersey
- Notice Date
- 5/8/2012
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541620
— Environmental Consulting Services
- Contracting Office
- Department of Health and Human Services, Centers for Disease Control and Prevention, Procurement and Grants Office (Atlanta), 2920 Brandywine Road, Room 3000, Atlanta, Georgia, 30341-4146
- ZIP Code
- 30341-4146
- Solicitation Number
- 00HCVLJC-2012-45948
- Archive Date
- 5/16/2012
- Point of Contact
- Linda M Young, Phone: (770) 488-2655
- E-Mail Address
-
lml3@cdc.gov
(lml3@cdc.gov)
- Small Business Set-Aside
- N/A
- Description
- The Centers for Disease Control and Prevention intends to issue a sole source purchase order to Terry L. Schulze, 9 Evergreen Court, Perrineville, NJ 08535 for Evaluation of the Host-Targeted Bait Box, Select Tick Control System (TCS) to reduce the Entomological Risk of Lyme Disease in a Lyme Endemic Area of North Central New Jersey. The Statement of Work is as follows: Background and Need - Lyme disease, caused by the spirochete Borrelia burgdorferi, and transmitted by the black-legged tick, Ixodes scapularis, is the most commonly reported vector-borne disease in the United States. Although chemical pesticides and repellents are available to combat these disease transmitting pests, many citizens are hesitant about the use of these pesticides due to concerns about short range toxicity and long range health problems attributed to these chemicals. DVBD scientists have developed host-targeted methods of controlling disease vectors thereby reducing populations of infected rodent reservoirs and questing ticks. Development of new, environmentally safe vector-control methods is a very high priority for DVBD and CDC. Because these DVBD patented, host-targeted bait boxes and other host-targeted technologies use such small amounts of pesticides enclosed in a box, they provide an especially eco-friendly method of vector-borne disease control in a residential setting. This is a win-win solution both for public health and the environment. CDC, DVBD scientists have developed and patented a host-targeted device containing a wick system that delivers the acaricide fipronil. These boxes lure rodents inside using non-toxic bait where they are passively treated. A single visit to a bait box can protect small mammals from tick and flea infestations for > 52 days. Initial studies were performed in DVBD laboratories followed by field trials in CT and most recently in NJ. A licensing agreement was recently signed with a tick control company and they have exclusive rights to the bait box technology (Tick Box Technology and Technology Transfer Office, CDC Atlanta). EPA required modifications to the originally patented design and we want to evaluate the newly registered Select Tick Control System® (TCS) boxes. The study will allow us to determine the efficacy of three modifications made to the original design that was evaluated in NJ: the recently changed wick delivery system, the non-toxic monitoring bait, and the galvanized steel protective shroud (proprietary design of Connecticut Tick Control and Tick Box Technology, Norwalk, CT). This continuation of proposed field research studies will allow CDC/DVBD to determine the efficacy of the Select TCS to impact the entomological risk of tick-borne disease when used alone or part of an overall integrated tick management (ITM) approach. Insight gained from these trials will also allow DVBD to make recommendations on the utility and efficacy of this device as a viable tick control product for public health. Project Objective - To evaluate the efficacy of modified Select TCS bait boxes containing the acaricide fipronil and the Connecticut Tick Control protective shroud device. The study will be conducted according to current product labeling and will determine the ability of these boxes as a stand-alone method of intervention to: 1) reduce tick infestation rates on small mammal reservoirs (Peromyscus leucopus, Tamias striatus, Sciurus carolinensis, and Blarina brevicauda), 2) reduce questing Ixodes scapularis tick populations, and 3) ability of host-targeted bait boxes to reduce infection rates in small mammal reservoirs as well as questing tick populations for both Borrelia burgdorferi (Bb) and Anaplasma phagocytophilum (Ap). Scope of Work - The vendor shall furnish all labor, materials and equipment necessary to evaluate the efficacy of Select TCS bait boxes. This will include but is not limited to all necessary equipment to perform rodent reservoir and questing tick evaluations. The vendor will need to have access to suitable tick/rodent/Lyme disease habitat with a minimum of 0.1 tick/m2 and adequate species of Peromyscus leucopus, Tamias striatus, Sciurus carolinensis, and Blarina brevicauda. The vendor shall furnish all labor, materials, processing equipment, live mammalian traps (Sherman and Tomahawk), bait boxes, and equipment necessary to evaluate the efficacy of doxycycline impregnated rodent bait to reduce infected rodent reservoirs and infected questing ticks in residential areas. The vendor will identify suitable test plots for each study, conduct weekly pre- and post-treatment flagging and trapping of animals in plots to determine the ability of these host-targeted technologies to reduce infected reservoirs, reduce the risk of tick-borne diseases, and evaluate host-targeted deployment strategies, and assist with obtaining all isolates for evaluation by PCR and culture. Vendor will provide monthly reports and perform statistical analysis. All data will be sent to CDC/NCEZID/DVBD, Fort Collins, CO. The DVBD contract PI will provide all additional equipment as needed to properly process and evaluate rodents and ticks for infection. This includes but is not limited to: BSK, specimen vials, animal processing equipment, tick collection and processing equipment, PCR analysis, culture and microscopy work, bait, bait boxes, shrouds, data collection, generation, and evaluation. The DVBD contract PI will oversee and assist grantees with all field trials until completed. Technical Requirements - The vendor shall perform the following tasks in the order shown: 1) Locate, measure, and stake a total of 10 1-3 ha residential properties (> 60% wooded) in Millstone Township, Monmouth County, New Jersey and at least 2 untreated control areas on Naval Weapons Station Earle, Colts Neck, NJ. The intervention and untreated areas must contain > 1 tick/m2. Preliminary trapping surveys must be conducted on each property and show abundant populations of ticks and small mammal hosts. The study will evaluate Select TCS which is a 19.05 cm x 13.97 cm x 6.35 cm child-resistant plastic box containing a non-toxic monitoring bait and a fipronil-treated felt wick assembly (0.7% AI, 3 ml total volume). After entering the box, the small mammals travel down the central corridor and are passively treated as they contact the wick while attempting to access the bait chambers. A single treatment is effective in killing ticks on small mammals for > 52 d. All Select TCS bait boxes need to have the following modification done. A 2-piece, tightly fitting protective cover constructed of 0.032 gauge galvanized steel will need to be installed over each box. The top and bottom sections of the clam-shell cover and bait box will be secured together at 2 opposite corners by means of 20.3 cm cable ties. The protected shroud is a proprietary device of Connecticut Tick Control Services, LLC (1 Testa Place, Norwalk, CT 06854). Bait boxes will be deployed on treatment areas according to product label and in accordance with suitable small mammal habitat and pre-treatment trapping. Approximate description of deployment: bait boxes should be deployed along 2 concentric rings, with the first located within the forest at ± 10 m from the lawn edge with a ± 25-m interval between individual boxes. Wherever possible, boxes should be placed in proximity to likely small mammal foraging or nesting sites. Because the combined weight of the bait box and protective covering exceeded 1200 g and are judged too heavy to be easily displaced by nuisance wildlife, the boxes should not need tethering. Pretreatment tick collections, flagging, and animal trapping will need to be completed in all areas before the end of May 2012. These plots will be sampled 2 times at weekly intervals to determine tick density, rodent density, rodent infestation rate, rodent infection rates, and tick infection rates prior to setting out bait boxes. Small mammals will be trapped using Sherman and Tomahawk live traps. All captures will be processed for materials and analyzed as follows: anesthetized, ear biopsied, bled by cheek punch, physical measurements recorded, ectoparisites removed and placed in ETOH, ear-tagged, and released at the capture site. Ear biopsies will be surface sterilized and cultured in BSK-H media for detection of live spirochetes by dark-field microscopy. Tick pools collected from rodents will be screened for infection by PCR. Both sites will be flagged for questing nymphal ticks. Ticks will be individually screened by PCR for infection with Bb. (Secondary future analysis will include PCR for Ap). Both areas will be flagged for questing ticks. Collected ticks will be recorded and analyzed by PCR. Bait boxes will need to be visited monthly during nymphal and larval season deployment and weighed in the field using a portable balance. Any change in box orientation or damage to boxes, including the acaricide wicks, should be noted for later replacement or repair. All efficacy data will be recorded for each time point and data will be analyzed, statistical analysis performed, and written report provided to CDC. All laboratory and field work should be performed under "Good Laboratory Practices" (GLP) guidelines as set forth by FDA and EPA. Animal work will need to be performed under an approved IACUC protocol on file at CDC, DVBD, BDB. Reporting Schedule - The period of performance shall commence upon receipt of a purchase order and shall continue for a period of 365 days. Special Considerations - The vendor must be fully familiar with the process of evaluating tick control technologies including host-targeted devices and rodent baits in a field setting. This includes but is not limited to: applying of chemicals, safety measures, locating and identifying suitable tick habitat, marking plots, flagging for questing ticks, proper times and conditions to flag for ticks, knowledge of deer ticks, lone star ticks, and Lyme disease, knowledge of trapping rodents, processing rodent tissues by culture for infection, assaying ticks and small mammal sera by PCR, evaluating baits and tick control using host-targeted devices such as bait boxes. The vendor must be able to conduct the study at weekly intervals and evaluate data using statistical analysis including the Henderson method for comparing efficacy of treated vs. control plots. Government Furnished Property -- See section C.3, Scope of Work paragraph 3. Deliverables - The vendor shall provide the following deliverables to the project officer by the dates shown: A. Locate, measure, stake 10, 1-3 ha properties in Perrineville, NJ and 2 untreated plots at NWSE, all pre-treatment trapping and flagging of both treated & un-treated plots. Process mammal and tick specimens for infection. - Before the end of May, 2012. B. Distribute bait boxes on treated properties during nymphal season. Bait boxes will be monitored at monthly intervals. Post-treatment trapping and flagging of all plots at 3-4 wk after deployment. Process mammal and tick specimens for infection. Provide written report to CDC, DVBD. - Before the end of May, 2012. C. Collect old bait boxes and distribute new bait boxes on treated properties during larval season. Bait boxes will be monitored at monthly intervals. Post-treatment trapping and flagging of all plots at 3-4 wk after deployment. Process mammal and tick specimens for infection. Provide written report to CDC, DVBD. - August 1, 2012. D. Flag treated and untreated properties for questing nymphal ticks. Collected nymphs will be analyzed for infection with Borrelia and anaplasmosis by PCR. A minimum of 50 nymphal ticks/test area will be needed for statistical analysis. Provide written report to CDC, DVBD. - May 2013. CDC believes that this requirement is met by only one provider. This procurement will be processed under the authority of FAR 13.106-1(b)(1). Only one responsible source and no other sources will satisfy agency requirements. No solicitation is being issued. Interested persons may use e-mail to identify their interest and capability to respond to this requirement before the expiration date of the advertisement. This procurement is not set-aside for small business. For contractual questions contact Linda M. Young.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/CDCP/PGOA/00HCVLJC-2012-45948/listing.html)
- Place of Performance
- Address: Perrinevile, NJ and evirons., Perrineville, New Jersey, 08535, United States
- Zip Code: 08535
- Zip Code: 08535
- Record
- SN02742337-W 20120510/120508235520-d907e2cf0141a7c277c0e3e2acd99c00 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |