SOURCES SOUGHT
Q -- Whole Genome Sequencing Services
- Notice Date
- 8/15/2012
- Notice Type
- Sources Sought
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Library of Medicine, 6707 Democracy Blvd., Suite 105, Bethesda, Maryland, 20894, United States
- ZIP Code
- 20894
- Solicitation Number
- NIHLM2012463-1
- Archive Date
- 9/5/2012
- Point of Contact
- Lisa S. Josephowitz, Phone: 3015947725
- E-Mail Address
-
josephol@mail.nih.gov
(josephol@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This Small Business Sources Sought Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation or commitment by the Government. The National Institutes of Health (NIH), National Library of Medicine Office of Acquisitions, NIDDK Acquisitions Branch, Phoenix, Arizona location, is conducting a market survey to determine the availability and technical capability of qualified small businesses, veteran-owned small businesses, service-disabled veteran-owned small businesses or HUBZone small businesses capable of providing the following service: Custom-whole-genome paired end sequencing at approximately 30-40x coverage and data analysis. This sequencing is required to determine the order of nucleotides of a gene. The NIDDK lab will provide DNA samples for whole-genome sequencing at approximately 30-40x coverage. The Contractor is to provide paired end sequencing and data analysis. The whole human genome sequencing performed at 30x average coverage, from short-insert paired end reads, using a single library. Data analysis will be performed using CASAVA (consensus sequence from ELAND alignment, called SNP's and small indels). The delivered data set will include reads and quality scores for further downstream analysis. Each sample requires the following specification: 1) Average autosomal minimum fold coverage of 30x, 2) Percent of non-N reference coverage>90% for non-cancer samples, 3) Paired end sequencing. Data shall be delivered in standard formats for downstream visualization in Genome Studio or third-party open-source tools, as follows: 1) All pass filter reads, alignments, and quality scores in an archival BAM format file, suitable for visualization and downstream analysis, 2) SNP calls, insertions and deletions with respect to the reference sequence, as well as an allele call and confidence score for every covered position in the reference, 3) Text reports for SNP calls for all SNP's in dbSNP for which sufficient coverage has been achieved. The reads from the samples are to be delivered within 4-6 months of receipt of the DNA samples. Interested firms with the capability of providing the required items are requested to submit a capability statement to assist the Government in determining in accordance with Federal Acquisition Regulation (FAR) 19.502-2(b) whether or not this procurement will be set-aside for any of the programs described above. The intended procurement will be classified under North American Industrial Classification (NAICS) code 541380 with a business size standard of $10M. All respondents are requested to identify their firm's size and type of business. Interested firms responding to this market survey must provide a capability statement demonstrating their experience, skills and capability to fulfill the Government's requirements for the above. The capability statement shall be in sufficient enough detail, but not to exceed 15 pages, so that the Government can determine the experience and capability of your firm to provide the requirements above. Your capability statement should include references. Three (3) copies of the capability statement must be received at the address identified in this synopsis on August 21, 2012. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provided feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate response to a solicitation. Confidentiality: "No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation (s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/OAM/NIHLM2012463-1/listing.html)
- Record
- SN02841584-W 20120817/120816001542-86191f80e6f7b65b1275a109ad47cb88 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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