SOLICITATION NOTICE
A -- Supplemental Iron and Gestational Diabetes
- Notice Date
- 8/22/2012
- Notice Type
- Presolicitation
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Executive Blvd., Suite 7A07, MSC7510, Bethesda, Maryland, 20892-7510
- ZIP Code
- 20892-7510
- Solicitation Number
- HHSN275201000020C
- Archive Date
- 9/20/2012
- Point of Contact
- Jacquelin M. Jones, Phone: 3014536965, Adelola Kellum, Phone: 3014356955
- E-Mail Address
-
jacquelin.jones@nih.gov, kelluml@mail.nih.gov
(jacquelin.jones@nih.gov, kelluml@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The Epidemiology Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), intends to negotiate, under the authority of 41 U.S.C. 253(c) (1) and FAR 6.302-1, a modification to its current contract no.HHSN275201000020Centitled "Diabetes Risk Across Women's Life Span." The purpose of this modification is to acquire the services capable of the investigation of "Dietary iron supplement intakes during pregnancy and the risk of gestational diabetes (GDM) and the underlying molecular mechanisms". The services will include 1). identifying longitudinal data on maternal diet and lifestyle factors during pregnancy before GDM develops; 2) examining the association of dietary iron supplements, in particular heme-iron supplements during peri-conception period and in mid pregnancy, with GDM risk, 3). measuring and analyzing biomarkers related to iron metabolism using blood samples collected before GDM to understand underlying molecular mechanisms among approximately 300 GDM cases and 300 non-GDM controls, 4) determining whether maternal conditions, such as iron deficiency anemia and menstruation history modify these associations, and 5). potentially evaluating the relationship between maternal supplemental and dietary iron in relation to timing of birth and fetal and early life growth of offspring born from a GDM pregnancy, as measured by birth weight and length in addition to longitudinal measures of height, weight and growth trajectory from infancy (6 and 18 months) through 7 years of age. In addition, upon the completion of the main study, the data can be used to examine how levels of iron metabolism biomarkers in pregnancy are related to women's future risk of developing type 2 diabetes at least 10 years after the index pregnancy. The NICHD anticipates that their services are congruent with the current services provided by Harvard University (with an existing subcontract to the Statens Serum Institut, Denmark) and the monitoring reports from these tasks will be incorporated into the already existing infrastructure for regulatory reporting for the ‘"Diabetes Risk Across Women's Life Span" Study. Background The existing ‘"Diabetes Risk Across Women's Life Span" Study infrastructure provides the efficient requisite of unique data and resources to address the above mentioned research aims. The scope of responsibilities include: 1). identifying longitudinal data on maternal diet and lifestyle factors and blood samples during pregnancy before GDM develops; 2) examining the association of dietary iron supplements, in particular heme-iron supplements during peri-conception period and in mid pregnancy, with GDM risk, 3). measuring and analyzing biomarkers related to iron metabolism using blood samples collected before GDM to understand underlying molecular mechanisms among approximately 300 GDM cases and 300 non-GDM controls, 4) determining whether maternal conditions, such as iron deficiency anemia and menstruation history modify these associations, and 5). potentially evaluating the relationship between maternal supplemental and dietary iron in relation to timing of birth and fetal and early life growth, as measured by birth weight and length in addition to longitudinal measures of height, weight and growth trajectory from infancy (6 and 18 months) through 7 years of age. In addition, upon the completion of the main study, the data can be used to examine how levels of iron metabolism biomarkers in pregnancy are related to women's future risk of developing type 2 diabetes 10 years after the index pregnancy. The NICHD anticipates that the services described above can only be done as part of the existing infrastructure of the Diabetes Risk across Women's Life Span study. Awarding a new contract to another contractor would require them to duplicate the infrastructure for regulatory reporting that already exists. This would result in unacceptable delays, substantial duplication of effort, and increased costs to the government. This is not a request for proposals. However, if any responsible source believes it can perform the above requirement, they may submit three (3) copies of their capability statement for consideration by the NICHD to Jacquelin Jones, Contract Specialist, NICHD, CMB, NIH, 6100 Executive Boulevard, MSC 7510, Bethesda, Maryland, 20892-7510 (or overnight courier: 6100 Executive Boulevard, Rockville, Maryland, 20852). Phone number (301) 435-6965, and fax number (301) 402-3676. Secondary point of contact is Adelola Kellum, Contracting Officer, NICHD, CMB, NIH, 6100 Executive Boulevard, MSC 7510, Bethesda, Maryland, 20892-7510 (or overnight courier: 6100 Executive Boulevard, Rockville, Maryland, 20852). Phone number (301) 435-6955, and fax number (301) 402-3676. All responses must be received in writing and must contain material in sufficient detail to allow the NICHD to determine if the party can perform this requirement. The capability statement will be considered solely for the purpose of determining whether to conduct a competitive procurement. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the government.
- Web Link
-
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- Record
- SN02850729-W 20120824/120823001109-dd003d08c6158775c90ec09e481adf70 (fbodaily.com)
- Source
-
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