SOURCES SOUGHT
R -- LactMed
- Notice Date
- 1/25/2013
- Notice Type
- Sources Sought
- NAICS
- 519190
— All Other Information Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Library of Medicine, 6707 Democracy Blvd., Suite 105, Bethesda, Maryland, 20894, United States
- ZIP Code
- 20894
- Solicitation Number
- NIHLM2013664
- Archive Date
- 2/14/2013
- Point of Contact
- Kimberly Pringle, Phone: 301-496-6546, Robin Hope, Phone: 301-496-6546
- E-Mail Address
-
kp271m@nih.gov, Robin.Hope@nih.gov
(kp271m@nih.gov, Robin.Hope@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. The North American Industry Classification System (NAICS) Code is 519190 with a small business size standard of $7 million. This Sources Sought Notice is for informational and planning purposes only and shall not be construed as an obligation or commitment by the Government. This notice is intended strictly for Market Research ONLY. 1. BACKGROUND This project relates to the continued building, updating, and maintenance of LactMed, a searchable database of records on drugs and their use during lactation. LactMed is an addition to the National Library of Medicine's (NLM) Toxicology and Environmental Health Information Program (TEHIP). Although TEHIP databases currently provide some information on drug pharmacology and toxicology, efforts are underway to enhance TEHIP with even greater information on the pharmacology and toxicology of drugs and related products. Drug information is an integral component of a comprehensive toxicology program, and expanded coverage complements existing chemical substance and other data records. The LactMed database is accessible through TOXNET, an Internet-based system for TEHIP online databases (http://toxnet.nlm.nih.gov), and is linked with other databases such as the Hazardous Substances Data Bank which has about 1,000 drug-related records. The LactMed database was created, and needs to continue to evolve, because information available to healthcare providers is usually derived from approved drug product labeling, which often differs from expert opinion. Of the relatively few sources of information on this subject, such labeling typically does not provide critical evaluations of the primary literature. An evidence-based, comprehensive database on drugs and lactation made available in the public domain, LactMed was designed to help support medical decision-making by healthcare professionals. The database is evidence-based with source attribution, and made available in the public domain. LactMed complements the suite of databases that comprise TOXNET, which is maintained by the Specialized Information Services (SIS) Division of NLM. Database records are linked, where appropriate, to other TOXNET and NLM database records. In order to ensure consistency and data currency, the Contractor will continue to build the database over the duration specified in this purchase order, for a period of one year, plus two optional extension years. The database is written primarily for healthcare professionals, with recommendations written at a level that is also understandable to consumers. 2. PURPOSE AND OBJECTIVES The rationale behind this project is to continue to expand and enhance LactMed, a database on possible adverse effects of prescription and nonprescription drugs, relevant herbals, nutraceuticals, and diagnostic agents in infants that result from transmission during human breast-feeding. The database needs to be a principal focus of the Contractor who has both the subject expertise and resources to accomplish this project expeditiously. 3. PROJECT REQUIREMENTS A. Compile the world's professional and scientific literature relating to the use of drugs and related products during human lactation. Organize this literature into a professionally acceptable system for ease of access to articles on specific drugs and, where appropriate, classes of pharmacologic and/or therapeutic agents. Drug names should be at the generic level and include, at a minimum, United States Adopted Names. Further, the Contractor must be willing to have such data placed in the public domain, without any intellectual property right constraints or fees imposed with respect to its use. While the database will become the property of NLM, this will not preclude the Contractor from reconfiguring or otherwise using the source data for preparing other information products or publications. The database content must be fully supported by an evidence-based approach that involves critical case evaluations of reports in peer-reviewed literature. B. At a minimum, database records should include the drug names specified above, drug class(es), pharmacologic and pharmacokinetic data such as drug concentrations in breast milk and infant serum, time course of such levels, and weight-adjusted percent of maternal dose in breast milk, when it can be determined from case report evaluations and other analyses of published literature, provide possible drug effects on maternal lactation and in breast-fed infants, indicating a quantifiable probable causation. Information should also be provided with respect to those drugs that present no safety problems if the scientific literature specifically makes that determination. All drug data within records must follow the approved drug record template, and be referenced to available source references. 4. ANTICIPATED PERIOD OF PERFORMANCE It is anticipated that the period of performance will be for one year from the date of award with two additional one-year option periods. 5. CAPABILITY STATEMENT/INFORMATION SOUGHT Capabilities of Organization Because of the high public health significance of the LactMed database, its importance to mothers and infants, and the need to ensure highly accurate and scientifically credible information and guidance, this project should be overseen by a world class expert on the effects of drugs on breastfeeding. Ideally, the candidate will be acknowledged as such by his peers, professional scientific societies, and the lactation community, and be widely published in the areas of drug use and breastfeeding. Service on relevant editorial boards or scientific advisory committees will also bolster the vendors credentials. The candidate should have a strong background in reviewing the scientific literature on drugs and lactation and be familiar in building online databases in this or related areas. The vendor should also be able to summarize retrieved data to offer guidance for breastfeeding mothers and their physicians on the advisability of continuing with certain medications and be able to suggest alternative products where warranted. A Doctor of Pharmacy degree might be a good educational platform upon which a vendor could establish drug and lactation expertise. Interested firms responding to this Sources Sought Notice must adhere to the following: (a) Provide a capability statement demonstrating relevant experience, skills, and ability to fulfill the Government's requirement. The capability statement should be complete and contain sufficient detail for the Government to make an informed decision regarding capabilities; however, the statement should not exceed 10 pages. (b) The capability statement must identify the responder's business type and size; DUNS number; NAICS code, and technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. (c) All capability statements must be submitted electronically no later than 12:00 pm local prevailing time on Wednesday, January 30, 2013 to Kimberly Pringle at pringlek@mail.nih.gov. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use the information provided by respondents for any purpose deemed necessary and legally appropriate. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary information in any resultant solicitation.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/OAM/NIHLM2013664/listing.html)
- Place of Performance
- Address: Contractor Site, United States
- Record
- SN02972394-W 20130127/130125234105-00c7994f99f15286deb10a69e7ffa9d4 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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