SOLICITATION NOTICE
66 -- Pre-Clinical Cryogen free 3.0 Tesla Multi-Nuclear MRI
- Notice Date
- 6/25/2013
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- NCI-130080-HN
- Archive Date
- 7/23/2013
- Point of Contact
- Huy Nguyen, Phone: 2402765570, Seena Ninan, Phone: 240-276-5419
- E-Mail Address
-
anh-huy.nguyen@nih.gov, ninans@mail.nih.gov
(anh-huy.nguyen@nih.gov, ninans@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive Room 1E154 Bethesda, MD 20892 Description: The Urologic Oncology Branch (UOB) and Radiation Biology Branch (RBB), National Cancer Institute (NCI) plans to procure on a sole source basis with Boston MR, Inc a cryogen free superconducting 3.0 Tesla Pre-Clinical MRI system to conduct metabolic MRI in mouse models of human cancer to characterize tumors either as implants or orthotopically placed. The tumors will be profiled based on how they convert an intravenously injected 13C labeled tracer such as 1-13C pyruvate after hyperpolarization. The conversion of pyruvate to products such as alanine, lactate, bicarbonate depending on the metabolic differences will be identified by 13C MRI images. These images will be co-registered with anatomic images from the same scanner using the 1H based images of anatomy. The products herein are being procured in accordance with the simplified acquisition procedures as authorized by FAR Part 13.106-1(b)(2). The North American Industry Classification System code is 334516 and the small business standard is 500 employees. Only one (1) award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. The Urologic Oncology Branch (UOB) and Radiation Biology Branch (RBB) at National Cancer Institute (NCI) has been granted a new initiative to conduct pre-clinical and clinical research profiling renal cell cancers using metabolic MRI and using this information to plan treatments using appropriate regimens. The metabolic MRI studies involve preparing 13C labeled metabolic tracers such as pyruvate, fumarate etc by hyperpolarization and injecting them in the subjects and following the breakdown products using 13C MRI. Laboratory space for this project has been chosen in Building 10, Room B3 B45. Based on the space allotted for this project, an MRI scanner is needed which can be accommodated adjacent to a polarizer in a room of 200 sq. ft area. A superconducting magnet using liquid helium would make it necessary for providing a helium escape from the B3 floor to ground level in case of a magnet quench. Therefore a required condition of the magnet in the scanner is that it should be cryogen free superconducting magnet capable of providing magnetic fields of up to 3 Tesla. The RF portion of the MRI scanner should have transmit and receive circuitry for 1H and 13C detection. Boston MR, Inc. is uniquely qualified in that it possess an MRI scanner with multiple channels for imaging 1H and 13C MRI using a cryogen free magnet which can be maintained at any magnetic field strength between 0.1 - 3.0 Tesla. Scanners from other sources are preset at a fixed value which cannot be changed. The magnet is cryogen free and uses a compressor and a cooler to achieve the desired fields. This avoids the use of superconducting magnets utilizing liquid helium which other manufacturers need to maintain the required field of 3.0 Tesla. Therefore there is no need of providing a quench pipe for this magnet for helium escape, as is the case for superconducting magnets. Providing a quench pipe from the lab at the B3 level to the ground level involves significant expense and this can be avoided with the MRI scanner from Boston MR. Additionally, the Boston MR scanner has a foot print small enough to be placed in the laboratory space allotted with sufficient space for the polarizer, console and for animal preparation prior to scanning. This is not a solicitation for competitive quotations. However, if any interested party, particularly small businesses, believe they can meet the above requirement, they may submit a electronic statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. The capability statement must be received in the NCI contracting office on or before 4:00 PM EST on July 8, 2013. All questions must be in writing and can be faxed (240)-276-5401 or emailed to Anh-Huy Nguyen, Contract Specialist at Anh-Huy.Nguyen@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) www.sam.gov. No collect calls will be accepted. Please reference solicitation number NCI-130080-HN on all correspondences.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-130080-HN/listing.html)
- Record
- SN03099619-W 20130627/130625235656-5c553b3ecfb727e87587e0f20f7206ac (fbodaily.com)
- Source
-
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