SOURCES SOUGHT
65 -- Ovation SP Ultralow DR Multiplex kits
- Notice Date
- 8/2/2013
- Notice Type
- Sources Sought
- NAICS
- 325199
— All Other Basic Organic Chemical Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-(SBSS)-2013-224-DDC
- Archive Date
- 8/31/2013
- Point of Contact
- Deborah - Coulter, Phone: (301) 435-0368
- E-Mail Address
-
dc143b@nih.gov
(dc143b@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources: (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantage businesses and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code (325199, size standard 1000) should not submit a response to this notice. 2. Notice Information a. Background: The NuGen Ovation SP Ultralow DR Multiplex kits are needed for the Framingham Heart Study (FHS) pilot RNA-Seq project. This project aims to obtain a deeper understanding of the CVD (cardiovascular disease) risk loci, which had been previously identified by genome-wide association study (GWAS). This will be achieved by characterizing patient transcriptome using the state-of-the-art RNA-Seq procedure. Transcriptome data will be analyzed primarily in CAD cases, including individuals with prior MI, other manifestations of CAD, and/or with high coronary artery calcium levels and in controls. Since the FHS RNA samples are precious specimen and are in very low quantity. These samples have to be pre-amplified before standard library construction. The NuGen Ovation kits requested serve as the critical reagent to generate double stranded cDNA from RNA samples with limited quantity. Based on a proprietary SPIA (single primer isothermal amplification) technique, the Ovation kit can yield microgram of double stranded cDNAs from nanogram and even subnanogram input of RNAs. Therefore, it is indispensable for the experimental implementation of the FHS RNA-Seq project, which is of great interest to NIH mission and health of the general public. b. Purpose and Objectives: The mission of the DIR DNA Sequencing and Genomics Core is to provide the NHLBI DIR investigators with cutting-edge sequencing technology to meet the increasing demands in genomics and epigenomics research. The core facility uses the NuGen technology. These instruments are responsible for high-throughput data acquisition. Before Sequencing can begin a high quality DNA Library must be constructed. NuGen Technologies provides the Mondrian, a high quality instrument to accomplish this task. The Ovation SP Ultralow DR Multiplex System and Cartridge is the reagent system designed for use with the Mondrian. These reagents provide automated production of multiplexed libraries starting with as little as 1ng of DNA. This acquisition is paramount to the cores ability to provide this service to the Institute. The DIR Sequencing and Genomics Core provides NextGen Sequencing services to more than 20 DIR laboratories. Without these reagents to perform Library Construction, DNA sequencing is not possible c. Contractor Requirements: The vendor will provide the Government the following products: *OvationSP Ultralow DR Multiplex System 1-8 quantity of 12 kits Catalog# 8133-32 Containing 8 unique barcoded adaptors for multiplex sequencing per kit Agencourt RNAClean XP beads Sample Concentration Solution * Contractor shall provide a letter from the manufacturer stating they are in authorized reseller d. Government Responsibilities DNA Sequencing and Genomics Core will ensure receiving of the kits, along with storage at 4C, under proper conditions. DNA Sequencing and Genomics Core will ensure the kits are used with the proper timeline before expiration date. e. Reporting Requirements and Deliverables: The estimated delivery time is 30 days after receipt of purchase order to the Government designated facility. f. Capability statement/Information sought: Based on the responses received from this SOURCES SOUGHT announcement, the proposed acquisition may be solicited as a Total Small Business Set-Aside. All eligible small business concerns responding to this Sources Sought Announcement must have the capabilities to provide services stated above. Interested small business firms are highly encouraged to respond to this notice. However, firms should understand that generic capability statements are not sufficient for effective evaluation of their capacity and capability to perform the work required. Responses must directly demonstrate the company's capability, experience, and ability to marshal resources to effectively and efficiently perform the objectives described above and include an outline of previous or similar projects so that the Government can perform a proper evaluation of the company's capability. Information regarding respondents': (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information; The written response to this notice should consist of the following items: a. Company Name. b. Company DUNS number. c. Company point of contact, mailing address, telephone and fax numbers, and website address d. Name, telephone number, and e-mail address of a company point of contact who has the authority and knowledge to clarify responses with government representatives e. Date submitted. f. Applicable company GSA Schedule number or other available procurement vehicle. g. Do you have a Government approved accounting system? If so, please identify the agency that approved the system. h. Type of Company (i.e., small business, 8(a), woman owned, veteran owned, etc.) as validated via the Central Contractor Registration (CCR). All respondents must register on the CCR located at http://www.ccr.gov/index.asp i. Not to exceed 20 singled-sided pages (including all attachments, resumes, charts, etc.) presented in single-space and using a 12 point font sized minimum, that clearly details the ability to perform the aspects of the notice described above. All proprietary information should be marked as such. Statements should also include an indication of current certified business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. j. Common cutoff date: 8/16/2013 2:30p.m. eastern time l. Delivery point: Submitted (via email) to Deborah Coulter, Contract Specialist at coulterd@nhlbi.nih.gov in MS Word or Adobe Portable Document Format (PDF). All responses must be received by the specified due date and time in order to be considered. 3. Disclaimer and Important Notes. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality - No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-(SBSS)-2013-224-DDC/listing.html)
- Place of Performance
- Address: NIH, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03136399-W 20130804/130802234749-2811c7d9fe97bcf4a86ab446c35fbf5d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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